4.7 Article

Biotransformation kinetics and pathways of typical synthetic progestins in soil microcosms

Related references

Note: Only part of the references are listed.
Article Environmental Sciences

Abiotic transformation of synthetic progestins in representative soil mineral suspensions

Xingjian Yang et al.

Summary: This study investigates the transformation of three synthetic progestins and the identification of their transformation products in different suspensions. It reveals that hydrophobic partitioning interaction plays a role in limiting the transformation and highlights the importance of identifying transformation products for risk assessment.

JOURNAL OF ENVIRONMENTAL SCIENCES (2023)

Article Environmental Sciences

Impacts of endocrine disrupting chemicals on reproduction in wildlife and humans

V. L. Marlatt et al.

Summary: This review summarizes the current knowledge of the impacts of EDCs on reproductive success in wildlife and humans, with a focus on retrospective assessment and laboratory-based experiments. The evidence suggests that anthropogenic chemicals negatively impact reproduction by altering endocrine system function, particularly in aquatic species. Similar effects are observed in mammalian wildlife and humans in epidemiological studies. Further research is needed on the implications of chemical exposures during development and the potential for long-term reproductive effects. Field-based observations and long-term population level studies are key to addressing knowledge gaps.

ENVIRONMENTAL RESEARCH (2022)

Article Engineering, Environmental

Radiolytic degradation of levonorgestrel and gestodene: Performance and bioassays

Juliana Mendonca Silva de Jesus et al.

Summary: This study investigates the feasibility of using ionizing sources to degrade progestins hormones in synthetic solutions and real pharmaceutical wastewater. The results show that LNG is more difficult to degrade compared to GES, and LNG exhibits greater reactivity with reducing species. Furthermore, the irradiation process reduces the toxicity of the substances to biological organisms.

PROCESS SAFETY AND ENVIRONMENTAL PROTECTION (2022)

Article Engineering, Environmental

Occurrence and removal of progestogens from wastewater treatment plants in China: Spatiotemporal variation and process comparison

Qingmiao Yu et al.

Summary: This study investigated the occurrence and variation of 19 progestogens in wastewater treatment plants (WWTPs) across China. The results showed that progestogens were widely detected in WWTPs, with certain progestogens consistently dominant in different samples. The study also found that there were significant seasonal and spatial variations in progestogen concentrations. Different treatment processes showed varying efficacies in progestogen removal, with the conventional process segment being the most effective. Biodegradation was identified as the primary removal pathway for progestogens.

WATER RESEARCH (2022)

Review Environmental Sciences

Synthetic Progestins in Waste and Surface Waters: Concentrations, Impacts and Ecological Risk

Maria Joao Rocha et al.

Summary: This review summarizes the concentrations of 12 synthetic progestins (PGs) in wastewater treatment plants and other matrices. PGs have been found to affect the reproductive fitness and development of biota, particularly in fish. However, research on the environmental concentrations and effects of PGs is still limited.

TOXICS (2022)

Article Engineering, Environmental

Fate and behavior of progestogens in activated sludge treatment: Kinetics and transformation products

Alexander Weizel et al.

Summary: Previous studies have demonstrated the high ecotoxicological potential of progestogens on aquatic organisms, with some compounds showing incomplete removal in wastewater treatment. Aerobic lab-scale experiments showed fast removal of most progestogens after 48 hours, but some compounds had slower degradation rates, hinting at limited removal in full-scale WWTPs. High-resolution mass spectrometry revealed numerous transformation products, showing complex degradation pathways for progestogens in wastewater treatment.

WATER RESEARCH (2021)

Article Engineering, Environmental

Biotransformation of Current-Use Progestin Dienogest and Drospirenone in Laboratory-Scale Activated Sludge Systems Forms High-Yield Products with Altered Endocrine Activity

Haoqi Nina Zhao et al.

Summary: Dienogest and drospirenone, two fourth-generation synthetic progestins widely used in oral contraceptives, undergo biotransformation during biological wastewater treatment to form various transformation products with potential environmental implications.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2021)

Article Environmental Sciences

Occurrence and distribution of natural and synthetic progestins, androgens, and estrogens in soils from agricultural production areas in China

Xingjian Yang et al.

Summary: This study investigated the widespread occurrence of 34 sex hormones in agriculture soils across different provinces in China, with androgens and progestins being the most dominant groups. Significant correlations were found between the concentrations of different types of sex hormones, suggesting similar sources. Population, poultry and swine slaughter, and soil organic carbon content were significantly correlated with the concentrations of sex hormones, indicating their contribution to the distribution in soils. Risk analysis showed medium to high risks posed by some sex hormones in agroecosystems, emphasizing the importance of optimizing manure fertilization strategies to mitigate these risks.

SCIENCE OF THE TOTAL ENVIRONMENT (2021)

Article Engineering, Environmental

Occurrence and fate of androg ens, progestogens and glucocorticoids in two swine farms with integrated wastewater treatment systems

Jin-Na Zhang et al.

Summary: This study investigated the occurrence and fate of steroid hormones in wastewater and feces from two swine farms in South China, revealing potential ecological risks posed by these hormones, especially some synthetic ones. The study also found that wastewater treatment systems in the swine farms were effective in removing most of the target steroid hormones, but some synthetic steroids still posed high risks to aquatic organisms.

WATER RESEARCH (2021)

Review Biochemistry & Molecular Biology

Emerging Patterns of Microbial Functional Traits

Yunfeng Yang

Summary: Functional traits are measurable characteristics that affect an organism's fitness under certain environmental conditions. They offer great potential for improving our ability to develop biogeochemical models and predict ecosystem responses to global changes in microbial ecology. These traits can be decoupled from taxonomic relatedness and are influenced by environmental changes, highlighting the need for further research and understanding in utilizing functional traits in microbial ecology.

TRENDS IN MICROBIOLOGY (2021)

Article Engineering, Environmental

Sorption, transport, and transformation of natural and synthetic progestins in soil-water systems

Xingjian Yang et al.

JOURNAL OF HAZARDOUS MATERIALS (2020)

Article Agriculture, Multidisciplinary

Degradation Kinetics and Transformation Products of Levonorgestrel and Quinestrol in Soils

Tao Tang et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2019)

Article Environmental Sciences

Persistence of androgens, progestogens, and glucocorticoids during commercial animal manure composting process

Jin-Na Zhang et al.

SCIENCE OF THE TOTAL ENVIRONMENT (2019)

Review Environmental Sciences

Attenuation, transport, and management of estrogens: A review

Xiaomin Zhao et al.

CHEMOSPHERE (2019)

Article Soil Science

The pH optimum of soil exoenzymes adapt to long term changes in soil pH

Jeremy Puissant et al.

SOIL BIOLOGY & BIOCHEMISTRY (2019)

Article Environmental Sciences

Do progestins contribute to (anti-)androgenic activities in aquatic environments?

Pavel Sauer et al.

ENVIRONMENTAL POLLUTION (2018)

Review Environmental Sciences

Occurrence of endocrine disrupting compounds in aqueous environment and their bacterial degradation: A review

Chi Zhang et al.

CRITICAL REVIEWS IN ENVIRONMENTAL SCIENCE AND TECHNOLOGY (2016)

Article Engineering, Environmental

Bioavailability and Fate of Sediment-Associated Progesterone in Aquatic Systems

Jodi L. Sangster et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2016)

Article Biotechnology & Applied Microbiology

Biodegradation of aflatoxin-B1 and zearalenone by Streptomyces sp collection

Peter Harkai et al.

INTERNATIONAL BIODETERIORATION & BIODEGRADATION (2016)

Review Engineering, Environmental

The Challenge Presented by Progestins in Ecotoxicological Research: A Critical Review

Vimal Kumar et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2015)

Article Environmental Sciences

Pharmaceuticals and other anthropogenic tracers in surface water: A randomized survey of 50 Minnesota lakes

Mark L. Ferrey et al.

ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY (2015)

Article Environmental Sciences

Fate of pharmaceutical compounds and steroid hormones in soil: study of transfer and degradation in soil columns

Marie-Virginie Salvia et al.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2014)

Article Agriculture, Multidisciplinary

Sorption and Mineral-Promoted Transformation of Synthetic Hormone Growth Promoters in Soil Systems

Shen Qu et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2014)

Review Biochemistry & Molecular Biology

Use of medroxyprogesterone acetate for hormone therapy in postmenopausal women: Is it safe?

Frank Z. Stanczyk et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2014)

Article Biotechnology & Applied Microbiology

Isolation of cholesterol- and deoxycholate-degrading bacteria from soil samples: evidence of a common pathway

E. Merino et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2013)

Article Environmental Sciences

Biotransformation of 17 alpha- and 17 beta-estradiol in aerobic soils

Michael L. Mashtare et al.

CHEMOSPHERE (2013)

Review Environmental Sciences

Microbial degradation of steroidal estrogens

Chang-Ping Yu et al.

CHEMOSPHERE (2013)

Article Engineering, Environmental

Several Synthetic Progestins with Different Potencies Adversely Affect Reproduction of Fish

Tamsin J. Runnalls et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2013)

Article Biotechnology & Applied Microbiology

Adsorption and aerobic biodegradation of four selected endocrine disrupting chemicals in soil-water system

Jianzhong Li et al.

INTERNATIONAL BIODETERIORATION & BIODEGRADATION (2013)

Article Biochemical Research Methods

UPARSE: highly accurate OTU sequences from microbial amplicon reads

Robert C. Edgar

NATURE METHODS (2013)

Article Agriculture, Multidisciplinary

Adsorption Properties and Degradation Dynamics of Endocrine-Disrupting Chemical Levonorgestrel in Soils

Tao Tang et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2012)

Article Engineering, Environmental

Steroids in a typical swine farm and their release into the environment

Shan Liu et al.

WATER RESEARCH (2012)

Article Biochemical Research Methods

FLASH: fast length adjustment of short reads to improve genome assemblies

Tanja Magoc et al.

BIOINFORMATICS (2011)

Article Biotechnology & Applied Microbiology

Isolation and characteristics of 17β-estradiol-degrading Bacillus spp. strains from activated sludge

Liying Jiang et al.

BIODEGRADATION (2010)

Article Biodiversity Conservation

Pharmaceuticals in the Aquatic Environment: Steroids and Anti-Steroids as High Priorities for Research

Tamsin J. Runnalls et al.

HUMAN AND ECOLOGICAL RISK ASSESSMENT (2010)

Article Environmental Sciences

Progestagens for human use, exposure and hazard assessment for the aquatic environment

Jean-Philippe Besse et al.

ENVIRONMENTAL POLLUTION (2009)

Article Engineering, Environmental

Determination and Source Apportionment of Five Classes of Steroid Hormones in Urban Rivers

Hong Chang et al.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2009)

Article Biotechnology & Applied Microbiology

17α-ethinylestradiol cometabolism by bacteria degrading estrone, 17β-estradiol and estriol

Bram Pauwels et al.

BIODEGRADATION (2008)

Article Multidisciplinary Sciences

Metagenomic signatures of the Peru Margin subseafloor biosphere show a genetically distinct environment

Jennifer F. Biddle et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

Comparative evaluation of androgen and progesterone receptor transcription selectivity indices of 19-nortestosterone-derived progestins

R García-Becerra et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2004)