4.4 Article

A Fluorescence Turn On-off-on Method for Sensitive Detection of Sn2+ and Glycine Using Waste Eggshell Membrane Derived Carbon Nanodots as Probe

Related references

Note: Only part of the references are listed.
Article Biochemical Research Methods

Rhodamine-based chemosensor for Sn2+ detection and its application in nanofibrous film and bioimaging

Yaqiong Kong et al.

Summary: In this study, a simple rhodamine-based compound CK was designed and synthesized as a fluorescent chemosensor for the detection of Sn2+. The probe showed quantitative detection of Sn2+ in the range of 10-30 μM, with a detection limit of 118 nM. It exhibited excellent biocompatibility and cell membrane permeability, enabling imaging of Sn2+ in HeLa cells and mice. Furthermore, CK-hybridized PMMA nanofibers were successfully employed for the visual detection of Sn2+ in actual samples.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2022)

Review Endocrinology & Metabolism

Effects of glycine on metabolic syndrome components: a review

M. Imenshahidi et al.

Summary: Glycine plays a crucial role in the development and treatment of metabolic syndrome. Studies have shown that plasma glycine levels are lower in patients with metabolic syndrome compared to healthy individuals. Interventions such as lifestyle modification, exercise, weight loss, or drug therapy can significantly increase circulating glycine concentrations.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION (2022)

Article Chemistry, Analytical

Fluorescent OFF-ON Sensors for the Detection of Sn2+ Ions Based on Amine-Functionalized Rhodamine 6G

Balamurugan Rathinam et al.

Summary: These structurally isomeric rhodamine 6G-based amino derivatives are designed for the detection of Sn2+ ions. They show rapid fluorescent turn-on responses towards Sn2+, with increased absorption and fluorescent intensity as the concentration of Sn2+ increases. The hydrazine derivative exhibits higher sensitivity towards Sn2+ compared to the ethylene diamine derivative, and the presence of carbonyl groups and terminal amino groups influences the sensitivity of the chemosensors through a spirolactam ring-opening mechanism. The receptors form 1:1 complexes with Sn2+ and have a limit of detection of 1.62 x 10(-7) M. The fluorescence images of the receptors and their complexes demonstrate their potential applications in the imaging of Sn2+ in real/online samples.

CHEMOSENSORS (2022)

Article Chemistry, Analytical

A highly branched macrocycle-based dual-channel sensor: Bodipy and pillar[5]arene combination for detection of Sn (II) &Hg (II) and bioimaging in living cells

Ahmed Nuri Kursunlu et al.

Summary: A highly branched pillar[5]arene-based sensor (B-P[5]arene) containing multiple BODIPY units has been designed and synthesized. Systematical experiments show that B-P[5]arene exhibits high sensitivity and selectivity to both Sn (II) and Hg (II) in acetonitrile/water. Hg (II) ions quench the fluorescence intensity of B-P[5]arene, while Sn (II) causes a broader spectrum without any shifting in wavelength.

ANALYTICA CHIMICA ACTA (2022)

Article Materials Science, Multidisciplinary

Green synthesis of carbon nanodots for direct and rapid determination of theophylline through fluorescence turn on-off strategy

Hongding Zhang et al.

Summary: This study reports an effective method for synthesizing carbon dots (CDs) with high quantum yield using waste chicken eggshell membrane as the carbon source via microwave-assisted technique, and the obtained CDs are designed as a fluorescent probe for the determination of theophylline concentration. The prepared CDs show good fluorescence performance and stability.

APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING (2022)

Article Chemistry, Analytical

Excitation-independent and fluorescence-reversible N-GQD for picomolar detection of inhibitory neurotransmitter in milk samples - an alleyway for possible neuromorphic computing application

V. Sravya et al.

Summary: N-GQDs with an average size of ca. 20-30 nm are utilized for the picomolar detection of inhibitory neurotransmitters, glycine (Gly), in pH ca. 7.0. The addition of Gly steadily quenches the fluorescence intensity of N-GQD due to inner filter effect (IFE) through the formation of ground-state complex. The excitation-independent N-GQDs showed outstanding selectivity and sensitivity towards Gly, and combinatorial logic circuits were developed based on the reversible fluorescence intensity changes.

TALANTA (2022)

Review Cell Biology

Regulation of Glucose, Fatty Acid and Amino Acid Metabolism by Ubiquitination and SUMOylation for Cancer Progression

Shunqin Zhu et al.

Summary: Ubiquitination and SUMOylation play important roles in regulating cellular functions and signal transduction pathways, especially in cancer metabolic reprogramming. Understanding the regulatory mechanisms of these processes is crucial for understanding the molecular mechanisms of cancer development and developing new treatment methods.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2022)

Article Biochemical Research Methods

A Turn Off Fluorescence Probe Based on Carbon Dots for Highly Sensitive Detection of BRCA1 Gene in Real Samples and Cellular Imaging

Meghdad Pirsaheb et al.

Summary: In this study, DNA-modified carbon dots were used to develop a fluorescence assay for the detection of breast cancer genes. The assay demonstrated high sensitivity and selectivity, allowing for the detection of the genes without the need for additional separation and washing steps. The method was successfully validated using real samples from breast cancer patients.

JOURNAL OF FLUORESCENCE (2022)

Article Spectroscopy

RhB-encapsulated metal-organic cage as a dual-emission fluorescence sensor for detection of malachite green and glycine

Xiao-Qing Wang et al.

Summary: RhB@ZrT-1-OH composite was developed as a dual-emission fluorescence sensor for highly sensitive detection of MG and Gly, and corresponding test papers were designed for concentration detection.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2022)

Article Chemistry, Analytical

High-Throughput Strategy for Glycine Oxidase Biosensor Development Reveals Glycine Release from Cultured Cells

Siba Moussa et al.

Summary: Glycine, an important biomarker in clinical analysis, has been detected using a Pt-based electrochemical enzymatic biosensor in this study, with the newly identified GO H244K variant showing increased glycine turnover. Notably, the biosensor achieved real-time measurements of glycine release from different cell types, with primary astrocytes showing fivefold higher glycine release compared to HEK 293 cells.

ANALYTICAL CHEMISTRY (2021)

Article Chemistry, Analytical

Simple Colorimetric and Fluorescence Chemosensing Probe for Selective Detection of Sn2+ Ions in an Aqueous Solution: Evaluation of the Novel Sensing Mechanism and Its Bioimaging Applications

Palanisamy Ravichandiran et al.

Summary: 4CBS is an easily accessible colorimetric and fluorescence probe for the selective and sensitive detection of Sn2+ in aqueous solutions. It shows a good linear relationship and low detection limit, with the binding mechanism to Sn2+ confirmed by FT-IR, NMR, and mass spectral analysis, and the proposed sensing mechanism supported by quantum chemical calculations. Additionally, 4CBS is effective for bioimaging studies and can discriminate between Sn2+ in human cancer cells and Sn2+ in normal live cells.

ANALYTICAL CHEMISTRY (2021)

Article Biochemical Research Methods

Green Synthesis of Self-Passivated Fluorescent Carbon Dots Derived from Rice Bran for Degradation of Methylene Blue and Fluorescent Ink Applications

Vinoth Kumar Jothi et al.

Summary: Natural products have been utilized as a powerful carbon source to synthesize carbon dots with interesting physical and chemical properties. A facile hydrothermal synthesis method using rice bran as a biogenic precursor was reported for preparing fluorescent carbon dots without any surface passivation agent. The synthesized RB-CDs exhibited green emission with a fluorescence quantum yield of 7.4% and were efficiently applied as a catalyst for the degradation of methylene blue dye, as well as a fluorescent ink for anti-counterfeiting applications.

JOURNAL OF FLUORESCENCE (2021)

Article Biophysics

Electrochemical biosensor for glycine detection in biological fluids

Qianyu Wang et al.

Summary: A novel amperometric biosensor for quantitative determination of glycine in diverse biological fluids was developed, showing fast response time, high specificity, and wide linear range. The biosensor design optimization and unique analytical features position it as a forefront technology for decentralized clinical applications and sport performance monitoring.

BIOSENSORS & BIOELECTRONICS (2021)

Article Chemistry, Analytical

Facile preparation of highly thermosensitive N-doped carbon dots and their detection of temperature and 6-mercaotopurine

Piao Chen et al.

Summary: Carbon dots (CDs) with attractive optical properties have been synthesized through a facile hydrothermal method to form thermosensitive N-doped carbon dots (N-CDs). These N-CDs exhibit high fluorescence quantum yield, small size, and good water solubility, making them suitable for temperature sensing. Additionally, N-CDs show potential as a fluorescent probe for selective detection of 6-mercaptopurine (6-MP) without any modification, with good recovery rates in lake water and serum samples.

MICROCHEMICAL JOURNAL (2021)

Article Materials Science, Multidisciplinary

Nitrogen, sulfur co-doped red carbon dots for sensitive and selective detection of Sn2+ ions

Peiyuan Zhu et al.

Summary: Novel R-CDs with strong red emission were successfully synthesized and utilized as a selective and sensitive turn-off sensor for Sn2+ detection. The R-CDs demonstrated effective electron, charge or energy transfer between excitons and Sn2+ through non-radiative recombination, enabling detection with a high range and low limit.

OPTICAL MATERIALS (2021)

Article Chemistry, Analytical

Posidonia oceanica (Mediterranean tapeweed) leaf litter as a source of fluorescent carbon dot preparations

Natalia-Maria Christopoulou et al.

Summary: Carbon dots are promising nanomaterials for novel analytical tools, with physicochemical properties determined by precursors and synthesis conditions. CD preparations from Posidonia oceanica leaf litter exhibit fluorescence properties and can be used as analytical reagents for detecting metal ions.

MICROCHEMICAL JOURNAL (2021)

Article Pharmacology & Pharmacy

Glycine/glycine N-methyltransferase/sarcosine axis mediates benzene-induced hematotoxicity

Wei Zhang et al.

Summary: The study aimed to explore the effects of benzene on metabolism, especially in amino acid metabolism, in human peripheral blood B lymphocyte cells treated with 1,4-benzoquinone (1,4-BQ) and in benzene-exposed population based on the untargeted and targeted metabolomics platforms. Results showed that 1,4-BQ disturbed metabolic activity, upregulated the ratio of sarcosine/glycine, and implied the involvement of the glycine/GNMT/sarcosine axis in benzene-induced hematotoxicity.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2021)

Review Oncology

Linking Serine/Glycine Metabolism to Radiotherapy Resistance

Anais Sanchez-Castillo et al.

Summary: Hyperactivation of the de novo serine/glycine biosynthesis pathway contributes to tumor initiation, progression, and therapy resistance across different cancer types. Inhibition of this pathway and serine-free diets may enhance the effectiveness of radiotherapy. Further research is needed to uncover the regulatory network of this pathway in cancer and develop stratification methods for personalized treatment approaches combining serine/glycine metabolism-targeted therapies with radiotherapy.

CANCERS (2021)

Article Spectroscopy

Preparation of a new fluorescence nanochemosensor for Sn(II) ions by a modified nanoprecipitation method

Reza Azadbakht et al.

Summary: A new organic nanoparticle was designed and synthesized using a modified nanoprecipitation method, which was able to detect low concentrations of Sn2+ ions with a small detection limit.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2021)

Article Chemistry, Inorganic & Nuclear

A dual-mode fluorescent probe based on perylene for the detection of Sn2+

Xin-Lu Ye et al.

Summary: SEPTD, a dual-mode fluorescent probe based on perylene, has been constructed and synthesized for the detection of Sn2+ in DMF solution, showing excellent selectivity and sensitivity. The probe exhibits a superior linear response for Sn2+ concentration in the range of 50 to 100 mu M, with a low detection limit of 0.168 mu M. The mechanism of SEPTD for detecting Sn2+ was investigated through H-1 NMR titration and IR spectra.

INORGANIC CHEMISTRY COMMUNICATIONS (2021)

Article Nanoscience & Nanotechnology

Glycine-Chitosan-Based Flexible Biodegradable Piezoelectric Pressure Sensor

Ensieh S. Hosseini et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Article Chemistry, Inorganic & Nuclear

A dual colorimetric chemosensor based on Schiff base for highly selective and simultaneous recognition of CN- and Sn2+

Pravin R. Dongare et al.

INORGANICA CHIMICA ACTA (2020)

Article Chemistry, Multidisciplinary

Green Synthesis of Carbon Dots toward Anti-Counterfeiting

Jiazhuang Guo et al.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2020)

Article Chemistry, Multidisciplinary

An ICT-based fluorescence enhancement probe for detection of Sn2+ in cancer cells

Xiangying Meng et al.

RSC ADVANCES (2020)

Review Nutrition & Dietetics

Glycine Metabolism and Its Alterations in Obesity and Metabolic Diseases

Anais Alves et al.

NUTRIENTS (2019)

Article Biochemistry & Molecular Biology

Glycine Transporter-1 and glycine receptor mediate the antioxidant effect of glycine in diabetic rat islets and INS-1 cells

Lei Chen et al.

FREE RADICAL BIOLOGY AND MEDICINE (2018)

Review Biochemistry & Molecular Biology

Insulin resistance and glycine metabolism in humans

M. Adeva-Andany et al.

AMINO ACIDS (2018)

Review Cell Biology

Multifarious Beneficial Effect of Nonessential Amino Acid, Glycine: A Review

Meerza Abdul Razak et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)

Article Crystallography

Compounds of glycine with halogen or metal halogenides: review and comparison

Michel Fleck

ZEITSCHRIFT FUR KRISTALLOGRAPHIE (2008)