Novel bioactive cationic cubosomes enhance the cytotoxic effect of paclitaxel against a paclitaxel resistant prostate cancer cell-line

Hypothesis The study aimed to use molecular hybridization of a cationic lipid with a known pharmacophore to produce a bifunctional lipid having a cationic charge to enhance fusion with the cancer cell surface and biological activity via the pharmacophoric head group.

Automated summary

The study aimed to create a bifunctional lipid with a cationic charge by combining a cationic lipid with a known pharmacophore, in order to enhance fusion with the cancer cell surface and biological activity through the pharmacophoric head group.