Journal
JOURNAL OF CELL BIOLOGY
Volume 222, Issue 7, Pages -Publisher
ROCKEFELLER UNIV PRESS
DOI: 10.1083/jcb.202306059
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The authors discuss a novel ESCRT-III structure discovered in migrating macrophages and dendritic cells, suggesting a new, cell type-specific function for this complex.
Conserved protein complexes called ESCRTs (endosomal sorting complexes in retrograde transport) exert diverse membrane remodeling and repair functions in cells. Hakala and Roux discuss a novel type of ESCRT-III structure found by Stempels et al. (2023. J. Cell Biol. https://doi.org/10.1083/jcb.202205130) in migrating macrophages and dendritic cells, suggesting a novel, cell type-specific function for this complex.
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