Related references
Note: Only part of the references are listed.In silico structure evaluation of BAG3 and elucidating its association with bacterial infections through protein-protein and host-pathogen interaction analysis
Soumya Basu et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2022)
ProThermDB: thermodynamic database for proteins and mutants revisited after 15 years
Rahul Nikam et al.
NUCLEIC ACIDS RESEARCH (2021)
The Role of the FMN-Domain of Human Cytochrome P450 Oxidoreductase in Its Promiscuous Interactions With Structurally Diverse Redox Partners
Francisco Esteves et al.
FRONTIERS IN PHARMACOLOGY (2020)
Insight into the structural and functional analysis of the impact of missense mutation on cytochrome P450 oxidoreductase
Rajalakshmi Kumar et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2020)
An integrated computational investigation to unveil the structural impacts of mutation on the InhA structural gene of Mycobacterium tuberculosis
Manikandan Jayaraman et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2020)
Molecular insights of the G2019S substitution in LRRK2 kinase domain associated with Parkinson's disease: A molecular dynamics simulation approach
Ashish Kumar Agrahari et al.
JOURNAL OF THEORETICAL BIOLOGY (2019)
Structural insight into conformational dynamics of non-active site mutations in KasA: A Mycobacterium tuberculosis target protein
Manikandan Jayaraman et al.
GENE (2019)
Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2
P. Sneha et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2018)
Substitution impact of highly conserved arginine residue at position 75 in GJB1 gene in association with X-linked Charcot-Marie-tooth disease: A computational study
Ashish Kumar Agrahari et al.
JOURNAL OF THEORETICAL BIOLOGY (2018)
Computational insights of K1444N substitution in GAP-related domain of NF1 gene associated with neurofibromatosis type 1 disease: a molecular modeling and dynamics approach
Ashish Kumar Agrahari et al.
METABOLIC BRAIN DISEASE (2018)
Computational modelling approaches as a potential platform to understand the molecular genetics association between Parkinson's and Gaucher diseases
D. Thirumal Kumar et al.
METABOLIC BRAIN DISEASE (2018)
Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450
Diana Campelo et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Molecular dynamics-based analyses of the structural instability and secondary structure of the fibrinogen gamma chain protein with the D356V mutation
Shabana Kouser Ali et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2017)
Two patients with Canavan disease and structural modeling of a novel mutation
Osama K. Zaki et al.
METABOLIC BRAIN DISEASE (2017)
Comparative computational assessment of the pathogenicity of mutations in the Aspartoacylase enzyme
C. George Priya Doss et al.
METABOLIC BRAIN DISEASE (2017)
Cytochrome P450 oxidoreductase deficiency caused by R457H mutation in POR gene in Chinese: case report and literature review
Yang Bai et al.
JOURNAL OF OVARIAN RESEARCH (2017)
The Hinge Segment of Human NADPH-Cytochrome P450 Reductase in Conformational Switching: The Critical Role of Ionic Strength
Diana Campelo et al.
FRONTIERS IN PHARMACOLOGY (2017)
Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype
Karen M. McCammon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules
Haim Ashkenazy et al.
NUCLEIC ACIDS RESEARCH (2016)
Principal component analysis: a review and recent developments
Ian T. Jolliffe et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES (2016)
mCSM: predicting the effects of mutations in proteins using graph-based signatures
Douglas E. V. Pires et al.
BIOINFORMATICS (2014)
Computational SNP Analysis: Current Approaches and Future Prospects
Ambuj Kumar et al.
CELL BIOCHEMISTRY AND BIOPHYSICS (2014)
Role of Protein-Protein Interactions in Cytochrome P450-Mediated Drug Metabolism and Toxicity
Sylvie E. Kandel et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2014)
DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach
Douglas E. V. Pires et al.
NUCLEIC ACIDS RESEARCH (2014)
Cytochrome P450 oxidoreductase deficiency: Rare congenital disorder leading to skeletal malformations and steroidogenic defects
Maki Fukami et al.
PEDIATRICS INTERNATIONAL (2014)
Pharmacogenomics of human P450 oxidoreductase
Amit V. Pandey et al.
FRONTIERS IN PHARMACOLOGY (2014)
Collective judgment predicts disease-associated single nucleotide variants
Emidio Capriotti et al.
BMC GENOMICS (2013)
Predicting the Functional, Molecular, and Phenotypic Consequences of Amino Acid Substitutions using Hidden Markov Models
Hashem A. Shihab et al.
HUMAN MUTATION (2013)
NADPH P450 oxidoreductase: Structure, function, and pathology of diseases
Amit V. Pandey et al.
PHARMACOLOGY & THERAPEUTICS (2013)
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
Ulrich M. Zanger et al.
PHARMACOLOGY & THERAPEUTICS (2013)
iStable: off-the-shelf predictor integration for predicting protein stability changes
Chi-Wei Chen et al.
BMC BIOINFORMATICS (2013)
NADPH-Cytochrome P450 Oxidoreductase: Roles in Physiology, Pharmacology, and Toxicology
David S. Riddick et al.
DRUG METABOLISM AND DISPOSITION (2013)
NADPH-cytochrome P450 oxidoreductase: Prototypic member of the diflavin reductase family
Takashi Iyanagi et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2012)
SIFT web server: predicting effects of amino acid substitutions on proteins
Ngak-Leng Sim et al.
NUCLEIC ACIDS RESEARCH (2012)
Predicting the Functional Effect of Amino Acid Substitutions and Indels
Yongwook Choi et al.
PLOS ONE (2012)
SDM-a server for predicting effects of mutations on protein stability and malfunction
Catherine L. Worth et al.
NUCLEIC ACIDS RESEARCH (2011)
Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency
Chuanwu Xia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Reduction in hepatic drug metabolizing CYP3A4 activities caused by P450 oxidoreductase mutations identified in patients with disordered steroid metabolism
Christa E. Flueck et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfaces
Hanka Venselaar et al.
BMC BIOINFORMATICS (2010)
GROMOS96 43a1 performance in predicting oligosaccharide conformational ensembles within glycoproteins
C. L. Fernandes et al.
CARBOHYDRATE RESEARCH (2010)
Restoration of mutant cytochrome P450 reductase activity by external flavin
Catherine Nicolo et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2010)
Substrate-specific modulation of CYP3A4 activity by genetic variants of cytochrome P450 oxidoreductase
Vishal Agrawal et al.
PHARMACOGENETICS AND GENOMICS (2010)
PoseView -- molecular interaction patterns at a glance
Katrin Stierand et al.
Journal of Cheminformatics (2010)
Principal Component Analysis for Protein Folding Dynamics
Gia G. Maisuradze et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap
Andrew D. Johnson et al.
BIOINFORMATICS (2008)
Pharmacogenetics of P450 oxidoreductase: effect of sequence variants on activities of CYP1A2 and CYP2C19
Vishal Agrawal et al.
PHARMACOGENETICS AND GENOMICS (2008)
P450 oxidoreductase deficiency and Antley-Bixler syndrome
Wiebke Arlt
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS (2007)
SNPs in disease gene mapping, medicinal drug development and evolution
Barkur S. Shastry
JOURNAL OF HUMAN GENETICS (2007)
Clinical, structural and functional implications of mutations and polymorphisms in human NADPH P450 oxidoreductase
Christa E. Flueck et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2007)
iPTREE-STAB: interpretable decision tree based method for predicting protein stability changes upon mutations
Liang-Tsung Huang et al.
BIOINFORMATICS (2007)
Predicting the insurgence of human genetic diseases associated to single point protein mutations with support vector machines and evolutionary information
E. Capriotti et al.
BIOINFORMATICS (2006)
CUPSAT: prediction of protein stability upon point mutations
Vijaya Parthiban et al.
NUCLEIC ACIDS RESEARCH (2006)
Prediction of protein stability changes for single-site mutations using support vector machines
JL Cheng et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2006)
I-Mutant2.0: predicting stability changes upon mutation from the protein sequence or structure
E Capriotti et al.
NUCLEIC ACIDS RESEARCH (2005)
Diversity and function of mutations in p450 oxidoreductase in patients with Antley-Bixler Syndrome and disordered steroidogenesis
NW Huang et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2005)
Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome
CE Flück et al.
NATURE GENETICS (2004)
PRODRG:: a tool for high-throughput crystallography of protein-ligand complexes
AW Schüttelkopf et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)
Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study
W Arlt et al.
LANCET (2004)
SIFT: predicting amino acid changes that affect protein function
PC Ng et al.
NUCLEIC ACIDS RESEARCH (2003)
Predicting crystal structures:: The Parrinello-Rahman method revisited -: art. no. 075503
R Martonák et al.
PHYSICAL REVIEW LETTERS (2003)
NADPH-cytochrome P450 oxidoreductase - Structural basis for hydride and electron transfer
PA Hubbard et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
dbSNP: the NCBI database of genetic variation
ST Sherry et al.
NUCLEIC ACIDS RESEARCH (2001)
Candidate genes and single nucleotide polymorphisms (SNPs) in the study of human disease
S Chanock
DISEASE MARKERS (2001)
Share Paper
