4.6 Article

TRIM28 negatively regulates the RLR signaling pathway by targeting MAVS for degradation via K48-linked polyubiquitination

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis

Rui Liu et al.

Summary: mTORC1 signaling inhibits GLDC acetylation at K514 by inducing SIRT3 transcription, which impairs its enzymatic activity and affects glycine metabolism and tumorigenesis.

NATURE COMMUNICATIONS (2021)

Review Immunology

Regulation of cGAS- and RLR-mediated immunity to nucleic acids

Andrea Ablasser et al.

NATURE IMMUNOLOGY (2020)

Review Oncology

TIF1 Proteins in Genome Stability and Cancer

Roisin M. McAvera et al.

CANCERS (2020)

Review Immunology

To TRIM the Immunity: From Innate to Adaptive Immunity

Wenyong Yang et al.

FRONTIERS IN IMMUNOLOGY (2020)

Article Biotechnology & Applied Microbiology

TRIM28 activates autophagy and promotes cell proliferation in glioblastoma

Yong Peng et al.

ONCOTARGETS AND THERAPY (2019)

Article Biology

KAP1 is an antiparallel dimer with a functional asymmetry

Giulia Fonti et al.

LIFE SCIENCE ALLIANCE (2019)

Article Immunology

TRIM29 Negatively Regulates the Type I IFN Production in Response to RNA Virus

Junji Xing et al.

JOURNAL OF IMMUNOLOGY (2018)

Article Biochemistry & Molecular Biology

KAP1 regulates endogenous retroviruses in adult human cells and contributes to innate immune control

Christopher H. C. Tie et al.

EMBO REPORTS (2018)

Article Biochemistry & Molecular Biology

The K48-K63 Branched Ubiquitin Chain Regulates NF-κB Signaling

Fumiaki Ohtake et al.

MOLECULAR CELL (2016)

Article Multidisciplinary Sciences

The mitochondrial ubiquitin ligase MARCH5 resolves MAVS aggregates during antiviral signalling

Young-Suk Yoo et al.

NATURE COMMUNICATIONS (2015)

Review Immunology

The role of ubiquitylation in immune defence and pathogen evasion

Xiaomo Jiang et al.

NATURE REVIEWS IMMUNOLOGY (2012)

Review Biochemistry & Molecular Biology

Autophagy: Renovation of Cells and Tissues

Noboru Mizushima et al.

Review Oncology

TRIM proteins and cancer

Shigetsugu Hatakeyama

NATURE REVIEWS CANCER (2011)

Article Biochemistry & Molecular Biology

MAGE-RING Protein Complexes Comprise a Family of E3 Ubiquitin Ligases

Jennifer M. Doyle et al.

MOLECULAR CELL (2010)

Review Immunology

RNA recognition and signal transduction by RIG-I-like receptors

Mitsutoshi Yoneyama et al.

IMMUNOLOGICAL REVIEWS (2009)

Review Cell Biology

Diversity of degradation signals in the ubiquitin-proteasome system

Tommer Ravid et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Physical and functional interactions between STAT3 and KAP1

R. Tsuruma et al.

ONCOGENE (2008)

Article Multidisciplinary Sciences

Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125

Kei-ichiro Arimoto et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

Michaela U. Gack et al.

NATURE (2007)