4.3 Article

Structure of rosettes in the zona glomerulosa of human adrenal cortex

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Summary: This article reviews the morphological features of the adrenal zona glomerulosa (zG) and recent cellular and molecular discoveries governing its formation, highlighting the organization of zG cells into rosettes and their impact on adrenal function. It discusses how rosettes arise through constriction at common cellular contact points and the role of adherens junctions in this process, as well as the invagination and folding of flat sheet-like domains in the nascent zG that give rise to compact round glomeruli in the adult zG.

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