Association between fear of progression and sleep quality in patients with chronic heart failure: A cross-sectional study

Aims: This study aimed to measure sleep quality and its possible association with fear of progression (FOP) in patients with chronic heart failure (HF). Design: A cross-sectional study. Methods: A total of 254 patients with chronic HF were recruited from two tertiary hospitals in China. The sociodemographic and clinical data of participants were collected using a general information questionnaire. The Pittsburgh Sleep Quality Index and Fear of Progression Questionnaire -Short Form were used to evaluate sleep quality over 1 month and FOP. Pearson correlation and hierarchical regression were conducted to analyse the relationship between sleep quality and FOP. Results: Of all participants, 85.8% had poor sleep quality, with a mean score of 12.3 +/- 4.2 (possible score could be 0 to 21). The severity of FOP was positively correlated with poor sleep quality. HF hospitalization in the past year, numbers of HF drugs, monthly income and total score of FOP were strong predictors of decreased sleep quality, accounting for 24.2% of the variance in the sleep quality of these patients. Conclusions: Patients with chronic HF generally reported poor sleep quality, which should be highly concerned for medical workers. Alleviating FOP as a therapeutic strategy may improve sleep quality. Impact: It is urgent to raise clinical attention that Chinese patients with chronic HF have poor sleep quality, which is not just due to the symptoms of HF itself. FOP is an important psychological factor influencing sleep quality in patients with chronic HF, which has not been explored in China. This study provides a new perspective on targeted interventions for poor sleep quality in chronic HF.

Automated summary

This study aimed to measure sleep quality and its association with fear of progression in patients with chronic heart failure. The results showed that patients with chronic heart failure generally reported poor sleep quality, and the severity of fear of progression was positively correlated with poor sleep quality. Several factors such as HF hospitalization, number of HF drugs, monthly income, and fear of progression score were strong predictors of decreased sleep quality in these patients.