4.7 Letter

Discontinuation of Conventional Synthetic Disease-Modifying Antirheumatic Drugs in Patients With Rheumatoid Arthritis and Excellent Disease Control

Journal

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Volume 329, Issue 12, Pages 1024-1026

Publisher

AMER MEDICAL ASSOC
DOI: 10.1001/jama.2023.0492

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This clinical trial investigated the risk of disease activity flares in rheumatoid arthritis patients who discontinued csDMARDs compared to those who continued with half-dose csDMARDs. The trial was open-label and randomized, and the follow-up period was 12 months.
This open-label randomized clinical trial assessed the 12-month risk of disease activity flares after discontinuation of conventional synthetic DMARDs (csDMARDs) compared with continuing half-dose csDMARDs in adult Norwegian patients with rheumatoid arthritis and excellent disease control.

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