Journal
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
Volume -, Issue -, Pages -Publisher
WILEY
DOI: 10.1111/1756-185X.14753
Keywords
amyloidosis; pulmonary nodule; Sjogren's syndrome
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There are few reported cases on the coexistence of Sjogren's syndrome and pulmonary nodular amyloidosis being treated with rituximab. However, it is important to consider amyloid lung when nodules with central calcification and cystic lesions are seen on computed tomography. Biopsy is recommended to differentiate it from malignancies. In this article, we present a case of a 66-year-old female patient with Sjogren's syndrome who had multiple cystic lesions with central calcification in the lung, confirmed as amyloid nodule through biopsy and stable under rituximab treatment. The rarity of pulmonary nodular amyloidosis in Sjogren patients and the limited use of rituximab for treatment make this case important for guiding clinicians.
There are very few cases in the literature on the coexistence of Sjogren's syndrome and pulmonary nodular amyloidosis being treated with rituximab. When nodules with central calcification and cystic lesions are seen on computed tomography, amyloid lung should be considered. Biopsy is recommended as it can be confused with malignancies. In this article, we present a 66-year-old female patient who has been followed up for Sjogren's syndrome for 26 years. Multiple cystic lesions with central calcification in the lung were detected and it was evaluated as amyloid nodule in the biopsy performed. The patient is being followed and is stable under rituximab treatment. Pulmonary noduler amyloidosis is very rare in Sjogren patients and there are very few cases where rituximab is used for treatment. We decided to publish in order to guide clinicians who will encounter similar cases.
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