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Harnessing the Potential of Non-Apoptotic Cell Death Processes in the Treatment of Drug-Resistant Melanoma

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Loss of the cystine/glutamate antiporter in melanoma abrogates tumor metastasis and markedly increases survival rates of mice

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CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

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Discovery of potent necroptosis inhibitors targeting RIPK1 kinase activity for the treatment of inflammatory disorder and cancer metastasis

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Delivery of Mixed-Lineage Kinase Domain-Like Protein by Vapor Nanobubble Photoporation Induces Necroptotic-Like Cell Death in Tumor Cells

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Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis

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miR-137 regulates ferroptosis by targeting glutamine transporter SLC1A5 in melanoma

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Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis

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Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells

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Autophagy promotes ferroptosis by degradation of ferritin

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Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth

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Necroptosis modulated by autophagy is a predominant form of melanoma cell death induced by sanguilutine

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The copper transporter CTR1 provides an essential function in mammalian embryonic development

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