☆ 4.7 Article

Eicosapentaenoic and Docosahexaenoic Acid Supplementation Increases HDL Content in n-3 Fatty Acids and Improves Endothelial Function in Hypertriglyceridemic Patients

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Related references

Note: Only part of the references are listed.

Review Peripheral Vascular Disease

Role of Omega-3 Fatty Acids in Cardiovascular Disease: the Debate Continues

Samuel C. R. Sherratt et al.

Summary: This review examines the effects of omega-3 fatty acids (n3-FAs) on cardiovascular risk reduction. It has been found that high-purity EPA ethyl ester has significant benefits in reducing cardiovascular events and atherosclerosis progression compared to mixed EPA/DHA treatments. Mechanistic differences between n3-FAs, including membrane interactions, metabolic products, cholesterol efflux, antioxidant properties, and tissue distribution, have been explored.

CURRENT ATHEROSCLEROSIS REPORTS (2023)

Add to Collection

Review Biochemistry & Molecular Biology

HDL as Bidirectional Lipid Vectors: Time for New Paradigms

Maria Luna-Luna et al.

Summary: The cardioprotective role of high-density lipoproteins (HDL) may not only be explained by reverse cholesterol transport, but also by bidirectional lipid transport. HDL plays an important role in tissue repair and cell function restoration. This hypothesis is consistent with the beneficial effects of HDL against atherosclerosis and its capacity to induce insulin secretion.

BIOMEDICINES (2022)

Add to Collection

Article Nutrition & Dietetics

Omega-3 Fatty Acids Improve Functionality of High-Density Lipoprotein in Individuals With High Cardiovascular Risk: A Randomized, Parallel, Controlled and Double-Blind Clinical Trial

Flavia De Conti Cartolano et al.

Summary: This study investigated the effects of Omega-3 on HDL functionality. The results showed that Omega-3 can effectively reduce cardiovascular risk associated with HDL functionality by improving its size and changing its lipid, antioxidant, and enzyme composition.

FRONTIERS IN NUTRITION (2022)

Add to Collection

Review Cardiac & Cardiovascular Systems

Coronary endothelial dysfunction: from pathogenesis to clinical implications

Lee Bockus et al.

Summary: Endothelial dysfunction plays a significant role in the pathogenesis of atherosclerosis and other vascular diseases. It can be caused by multiple risk factors and is correlated with cardiac events. Invasive techniques are required to measure coronary artery endothelial function, but peripheral vascular techniques and endothelial biomarkers can be used as indirect assessments.

OPEN HEART (2022)

Add to Collection

Article Nutrition & Dietetics

Effects of omega-3 supplementation on endothelial function, vascular structure, and metabolic parameters in adolescents with type 1 diabetes mellitus: A randomized clinical trial

Masoud Khorshidi et al.

Summary: This study found that omega-3 supplementation can improve vascular function and reduce triglyceride levels in adolescents with T1DM, potentially reducing the risk of cardiovascular disease.

FRONTIERS IN NUTRITION (2022)

Add to Collection

Article Ophthalmology

Pharmacokinetics and metabolism in mouse retina of bis-allylic deuterated docosahexaenoic acid (D-DHA), a new dry AMD drug candidate

Genevieve James et al.

Summary: D-DHA, a compound with higher resistance to oxidative damage, has the potential to treat eye diseases. By consuming D-DHA, it can replace natural DHA in the body and rapidly accumulate in ocular tissues, achieving therapeutic effects.

EXPERIMENTAL EYE RESEARCH (2022)

Add to Collection

Article Nutrition & Dietetics

Association between the ratio of serum eicosapentaenoic acid to arachidonic acid and risk of coronary artery disease in young Chinese patients

Xiong Liu et al.

Summary: The study found that higher AA levels were associated with an increased risk of CAD, while lower EPA levels were linked to CAD. The ratios of EPA and DHA to AA were lower in CAD patients, suggesting a potential protective effect. EPA was found to have a protective role in CAD, while AA was associated with an increased risk.

FRONTIERS IN NUTRITION (2022)

Add to Collection

Article Cell Biology

Prostaglandin E3 attenuates macrophage-associated inflammation and prostate tumour growth by modulating polarization

Jing Cui et al.

Summary: This study reveals that PGE(3) can inhibit inflammation and has anti-tumor effects by regulating the polarization of macrophages. Experimental results show that PGE(3) can inhibit the growth of prostate cancer cells in vivo and in vitro, and also suppress tumor-associated M2 macrophages.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)

Add to Collection

Article Biochemistry & Molecular Biology

Trp Fluorescence Redshift during HDL Apolipoprotein Denaturation Is Increased in Patients with Coronary Syndrome in Acute Phase: A New Assay to Evaluate HDL Stability

Victoria Lopez-Olmos et al.

Summary: The study established a method to assess HDL stability based on fluorescence spectrum redshift, finding that HDL from ACS patients had significantly higher denaturation percentages compared to healthy individuals, with stability correlating with BMI and plasma activity markers. The study suggests that HDL composition is a major determinant of stability, and that denaturation percentage can predict the presence of ACS.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Endothelial Spns2 and ApoM Regulation of Vascular Tone and Hypertension Via Sphingosine-1-Phosphate

Ilaria Del Gaudio et al.

Summary: This study highlights the significant role of endothelial-derived S1P and ApoM-HDL in regulating blood pressure homeostasis through S1P-NO signaling, and their pathological impact on hypertension and cardiac hypertrophy.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2021)

Add to Collection

Article Medicine, General & Internal

Relationship between high-density lipoprotein cholesterol levels and endothelial function in women: a cross-sectional study

Yuji Takaeko et al.

BMJ OPEN (2020)

Add to Collection

Article Nutrition & Dietetics

Daily supplementation with fresh pomegranate juice increases paraoxonase 1 expression and activity in mice fed a high-fat diet

D. Estrada-Luna et al.

EUROPEAN JOURNAL OF NUTRITION (2018)

Add to Collection

Article Cardiac & Cardiovascular Systems

Treatment with omega-3 polyunsaturated fatty acids does not improve endothelial function in patients with type 2 diabetes and very high cardiovascular risk: A randomized, double-blind, placebo-controlled study (Omega-FMD)

Aleksander Siniarski et al.

ATHEROSCLEROSIS (2018)

Add to Collection

Review Biochemistry & Molecular Biology

Omega-3 polyunsaturated fatty acids improve endothelial function in humans at risk for atherosclerosis: A review

Kayla R. Zehr et al.

PROSTAGLANDINS & OTHER LIPID MEDIATORS (2018)

Add to Collection

Article Biochemistry & Molecular Biology

HDL-Mediated Lipid Influx to Endothelial Cells Contributes to Regulating Intercellular Adhesion Molecule (ICAM)-1 Expression and eNOS Phosphorylation

Monica Munoz-Vega et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Add to Collection

Article Peripheral Vascular Disease

Elevated Monocyte to High-Density Lipoprotein Cholesterol Ratio and Endothelial Dysfunction in Behcet Disease

Nusret Acikgoz et al.

ANGIOLOGY (2018)

Add to Collection

Article Medical Laboratory Technology

Small HDL subclasses become cholesterol-poor during postprandial period after a fat diet intake in subjects with high triglyceridemia increases

Armando Quintanilla-Cantu et al.

CLINICA CHIMICA ACTA (2017)

Add to Collection

Article Biochemistry & Molecular Biology

Eicosapentaenoic acid reduces membrane fluidity, inhibits cholesterol domain formation, and normalizes bilayer width in atherosclerotic-like model membranes

R. Preston Mason et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2016)

Add to Collection

Review Oncology

Omega-3 fatty acids for breast cancer prevention and survivorship

Carol J. Fabian et al.

BREAST CANCER RESEARCH (2015)

Add to Collection

Article Peripheral Vascular Disease

Long-Chain Omega-3 Fatty Acids Eicosapentaenoic Acid and Docosahexaenoic Acid and Blood Pressure: A Meta-Analysis of Randomized Controlled Trials

Paige E. Miller et al.

AMERICAN JOURNAL OF HYPERTENSION (2014)

Add to Collection

Article Cardiac & Cardiovascular Systems

Omega-3 PUFAs improved endothelial function and arterial stiffness with a parallel antiinflammatory effect in adults with metabolic syndrome

Dimitris Tousoulis et al.

ATHEROSCLEROSIS (2014)

Add to Collection

Review Cardiac & Cardiovascular Systems

High-density lipoproteins as modulators of endothelial cell functions: alterations in patients with coronary artery disease

Adelheid Kratzer et al.

CARDIOVASCULAR RESEARCH (2014)

Add to Collection

Article Nutrition & Dietetics

Early endothelial nitrosylation and increased abdominal adiposity in Wistar rats after long-term consumption of food fried in canola oil

Rocio Bautista et al.

NUTRITION (2014)

Add to Collection

Article Biophysics

Interfacial Properties of High-Density Lipoprotein-like Lipid Droplets with Different Lipid and Apolipoprotein A-I Compositions

Artturi Koivuniemi et al.

BIOPHYSICAL JOURNAL (2013)

Add to Collection

Article Cardiac & Cardiovascular Systems

Effects of omega-3 fatty acids on endothelial function, arterial wall properties, inflammatory and fibrinolytic status in smokers: A cross over study

Gerasimos Siasos et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2013)

Add to Collection

Article Neurosciences

Red blood cell omega-3 fatty acid levels and neurocognitive performance in deployed US Servicemembers

Daniel T. Johnston et al.

NUTRITIONAL NEUROSCIENCE (2013)

Add to Collection

Article Multidisciplinary Sciences

Omega-3 fatty acids lower blood pressure by directly activating large-conductance Ca2+-dependent K+channels

Toshinori Hoshi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Add to Collection

Article Endocrinology & Metabolism

Effect of the Treatment with Allopurinol on the Endothelial Function in Patients with Hyperuricemia

Gabriela Melendez-Ramirez et al.

ENDOCRINE RESEARCH (2012)

Add to Collection

Article Cardiac & Cardiovascular Systems

Long-term association of brachial artery flow-mediated vasodilation and cardiovascular events in middle-aged subjects with no apparent heart disease

Michael Shechter et al.

INTERNATIONAL JOURNAL OF CARDIOLOGY (2009)

Add to Collection

Article Cardiac & Cardiovascular Systems

Prognostic role of flow-mediated dilation and cardiac risk factors in post-menopausal women

Rosario Rossi et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2008)

Add to Collection

Article Cardiac & Cardiovascular Systems

Is the association between flow-mediated dilation and cardiovascular risk limited to low-risk populations?

DR Witte et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2005)

Add to Collection

Article Cardiac & Cardiovascular Systems

Prognostic role of reversible endothelial dysfunction in hypertensive postmenopausal women

MG Modena et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2002)

Add to Collection

Article Cardiac & Cardiovascular Systems

Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery - A report of the International Brachial Artery Reactivity Task Force

MC Corretti et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2002)

Add to Collection

Article Cardiac & Cardiovascular Systems

Dietary supplementation with marine omega-3 fatty acids improve systemic large artery endothelial function in subjects with hypercholesterolemia

J Goodfellow et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2000)

Add to Collection

© Peeref 2019-2024. All rights reserved.