☆ 4.7 Review

Prospects and Advances in Adoptive Natural Killer Cell Therapy for Unmet Therapeutic Needs in Pediatric Bone Sarcomas

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

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Robbie G. Majzner et al.

CLINICAL CANCER RESEARCH (2019)

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Review Endocrinology & Metabolism

Long-Term Endocrine and Metabolic Consequences of Cancer Treatment: A Systematic Review

Judith Gebauer et al.

ENDOCRINE REVIEWS (2019)

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Review Oncology

Compare and contrast: pediatric cancer versus adult malignancies

Patricia Kattner et al.

CANCER AND METASTASIS REVIEWS (2019)

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Article Biochemistry & Molecular Biology

Super-enhancer-associated MEIS1 promotes transcriptional dysregulation in Ewing sarcoma in co-operation with EWS-FLI1

Lehang Lin et al.

NUCLEIC ACIDS RESEARCH (2019)

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Article Oncology

NK Cells Expressing a Chimeric Activating Receptor Eliminate MDSCs and Rescue Impaired CAR-T Cell Activity against Solid Tumors

Robin Parihar et al.

CANCER IMMUNOLOGY RESEARCH (2019)

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Article Oncology

Programmed cell death ligand 1 (PD-L1) expression is not a predominant feature in Ewing sarcomas

Christian Spurny et al.

PEDIATRIC BLOOD & CANCER (2018)

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Article Hematology

First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation

Rizwan Romee et al.

BLOOD (2018)

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Article Biochemical Research Methods

The Ewing Sarcoma Secretome and Its Response to Activation of Wnt/beta-catenin Signaling

Allegra G. Hawkins et al.

MOLECULAR & CELLULAR PROTEOMICS (2018)

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Article Immunology

Peptide-specific recognition of human cytomegalovirus strains controls adaptive natural killer cells

Quirin Hammer et al.

NATURE IMMUNOLOGY (2018)

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Review Oncology

Osteosarcoma: Accelerating Progress Makes for a Hopeful Future

Amanda J. Saraf et al.

FRONTIERS IN ONCOLOGY (2018)

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Review Oncology

Tumour-associated antigens and their anti-cancer applications

C-C. Liu et al.

EUROPEAN JOURNAL OF CANCER CARE (2017)

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Article Oncology

Targeting Ewing sarcoma with activated and GD2-specific chimeric antigen receptor-engineered human NK cells induces upregulation of immune-inhibitory HLA-G

Sareetha Kailayangiri et al.

ONCOIMMUNOLOGY (2017)

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Article Oncology

A phase II trial evaluating the feasibility of adding bevacizumab to standard osteosarcoma therapy

Fariba Navid et al.

INTERNATIONAL JOURNAL OF CANCER (2017)

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Article Oncology

International incidence of childhood cancer, 2001-10: a population-based registry study

Eva Steliarova-Foucher et al.

LANCET ONCOLOGY (2017)

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Article Oncology

Myeloid-Derived Suppressor Cells

Dmitry I. Gabrilovich

CANCER IMMUNOLOGY RESEARCH (2017)

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Article Oncology

Adoptive natural killer cell therapy is effective in reducing pulmonary metastasis of Ewing sarcoma

Alexander A. Tong et al.

ONCOIMMUNOLOGY (2017)

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Article Oncology

Inhibition of IL-18-mediated myeloid derived suppressor cell accumulation enhances anti-PD1 efficacy against osteosarcoma cancer

Ying Guan et al.

JOURNAL OF BONE ONCOLOGY (2017)

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Article Oncology

Blocking Tumor-Educated MSC Paracrine Activity Halts Osteosarcoma Progression

S. Rubina Baglio et al.

CLINICAL CANCER RESEARCH (2017)

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Review Pharmacology & Pharmacy

A Review of Ewing Sarcoma Treatment: Is it Still a Subject of Debate?

Wala Ben Kridis et al.

REVIEWS ON RECENT CLINICAL TRIALS (2017)

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Article Oncology

NK-92: an 'off-the-shelf therapeutic' for adoptive natural killer cell-based cancer immunotherapy

Garnet Suck et al.

CANCER IMMUNOLOGY IMMUNOTHERAPY (2016)

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Article Oncology

Phase I Clinical Trial of Ipilimumab in Pediatric Patients with Advanced Solid Tumors

Melinda S. Merchant et al.

CLINICAL CANCER RESEARCH (2016)

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Article Orthopedics

Transcriptional Profiling Identifies the Signaling Axes of IGF and Transforming Growth Factor-β as Involved in the Pathogenesis of Osteosarcoma

Rui Yang et al.

CLINICAL ORTHOPAEDICS AND RELATED RESEARCH (2016)

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Article Cell & Tissue Engineering

Induced Pluripotent Stem Cell-Derived Natural Killer Cells for Treatment of Ovarian Cancer

David L. Hermanson et al.

STEM CELLS (2016)

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Review Pharmacology & Pharmacy

Genome Editing: A New Approach to Human Therapeutics

Matthew Porteus

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 56 (2016)

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Article Cell Biology

Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia

Rizwan Romee et al.

SCIENCE TRANSLATIONAL MEDICINE (2016)

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Article Oncology

Overexpression of EZH2 is associated with the poor prognosis in osteosarcoma and function analysis indicates a therapeutic potential

Ranran Sun et al.

ONCOTARGET (2016)

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Article Oncology

Reduction of MDSCs with All-trans Retinoic Acid Improves CAR Therapy Efficacy for Sarcomas

Adrienne H. Long et al.

CANCER IMMUNOLOGY RESEARCH (2016)

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Review Immunology

Natural Killer Cells for immunotherapy-Advantages of the NK-92 Cell Line over Blood NK Cells

Hans Klingemann et al.

FRONTIERS IN IMMUNOLOGY (2016)

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Article Multidisciplinary Sciences

Immune infiltration and PD-L1 expression in the tumor microenvironment are prognostic in osteosarcoma

Pratistha Koirala et al.

SCIENTIFIC REPORTS (2016)

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Review Oncology

Tumor microenvironment: Sanctuary of the devil

Lanlan Hui et al.

CANCER LETTERS (2015)

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Article Oncology

Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial

Stefan S. Bielack et al.

JOURNAL OF CLINICAL ONCOLOGY (2015)

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Review Oncology

Ewing Sarcoma: Current Management and Future Approaches Through Collaboration

Nathalie Gaspar et al.

JOURNAL OF CLINICAL ONCOLOGY (2015)

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Article Immunology

NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype

Erik Ames et al.

JOURNAL OF IMMUNOLOGY (2015)

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Article Biochemistry & Molecular Biology

Ionizing Radiation Stimulates Expression of Pro-Osteoclastogenic Genes in Marrow and Skeletal Tissue

Joshua S. Alwood et al.

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2015)

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Article Multidisciplinary Sciences

Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity

Jie Yin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

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Article Oncology

CD8+/FOXP3+-ratio in osteosarcoma microenvironment separates survivors from non-survivors: a multicenter validated retrospective study

Benedikt Fritzsching et al.

ONCOIMMUNOLOGY (2015)

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Article Oncology

Increased CTLA-4+ T cells and an increased ratio of monocytes with loss of class II (CD14+ HLA-DRlo/neg) found in aggressive pediatric sarcoma patients

Pooja Hingorani et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2015)

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Article Multidisciplinary Sciences

The Macrophage Inhibitor CNI-1493 Blocks Metastasis in a Mouse Model of Ewing Sarcoma through Inhibition of Extravasation

Anthony J. Hesketh et al.

PLOS ONE (2015)

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Article Oncology

Ganglioside GD2 as a Therapeutic Target for Antibody-Mediated Therapy in Patients With Osteosarcoma

Michael Roth et al.

CANCER (2014)

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Article Oncology

Circulating T-Regulatory Cells in PNET: A Prospective Study

T. V. S. V. G. K. Tilak et al.

PEDIATRIC BLOOD & CANCER (2014)

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Article Oncology

Analysis of Serum Insulin Growth Factor-1 Concentrations in Localized Osteosarcoma: A Children's Oncology Group Study

Scott C. Borinstein et al.

PEDIATRIC BLOOD & CANCER (2014)

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Review Immunology

NK cell self tolerance, responsiveness and missing self recognition

Nataliya Shifrin et al.

SEMINARS IN IMMUNOLOGY (2014)

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Article Cell & Tissue Engineering

Bone Environment is Essential for Osteosarcoma Development from Transformed Mesenchymal Stem Cells

Ruth Rubio et al.

STEM CELLS (2014)

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Review Immunology

Innate and adaptive immune cells in the tumor microenvironment

Thomas F. Gajewski et al.

NATURE IMMUNOLOGY (2013)

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Article Multidisciplinary Sciences

Bone Marrow Stromal Cells Derived MCP-1 Reverses the Inhibitory Effects of Multiple Myeloma Cells on Osteoclastogenesis by Upregulating the RANK Expression

Zhiqiang Liu et al.

PLOS ONE (2013)

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Review Immunology

Natural killer cells: walking three paths down memory lane

Gundula Min-Oo et al.

TRENDS IN IMMUNOLOGY (2013)

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Article Oncology

Significant association between cytotoxic T lymphocyte antigen 4+49G>A polymorphism and risk of malignant bone tumors

Fengbin Yu et al.

TUMOR BIOLOGY (2013)

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Article Cell & Tissue Engineering

Clinical-Scale Derivation of Natural Killer Cells From Human Pluripotent Stem Cells for Cancer Therapy

David A. Knorr et al.

STEM CELLS TRANSLATIONAL MEDICINE (2013)

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Review Oncology

Understanding the biology of bone sarcoma from early initiating events through late events in metastasis and disease progression

Limin Zhu et al.

FRONTIERS IN ONCOLOGY (2013)

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Article Oncology

The ganglioside antigen GD2 is surface-expressed in Ewing sarcoma and allows for MHC-independent immune targeting

S. Kailayangiri et al.

BRITISH JOURNAL OF CANCER (2012)

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Review Cell Biology

Modeling sarcomagenesis using multipotent mesenchymal stem cells

Rene Rodriguez et al.

CELL RESEARCH (2012)

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Article Hematology

Natural killer cells can exert a graft-vs-tumor effect in haploidentical stem cell transplantation for pediatric solid tumors

Antonio Perez-Martinez et al.

EXPERIMENTAL HEMATOLOGY (2012)

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Article Immunology

The unique profile of cord blood natural killer cells balances incomplete maturation and effective killing function upon activation

Martha Luevano et al.

HUMAN IMMUNOLOGY (2012)

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Review Biochemistry & Molecular Biology

TGF-β and BMP Signaling in Osteoblast Differentiation and Bone Formation

Guiqian Chen et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2012)

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Article Pathology

Macrophage Infiltration Predicts a Poor Prognosis for Human Ewing Sarcoma

Toshifumi Fujiwara et al.

AMERICAN JOURNAL OF PATHOLOGY (2011)

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Article Oncology

Chemotherapy-resistant osteosarcoma is highly susceptible to IL-15-activated allogeneic and autologous NK cells

Emilie P. Buddingh et al.

CANCER IMMUNOLOGY IMMUNOTHERAPY (2011)

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Review Biotechnology & Applied Microbiology

Methotrexate Toxicity in Growing Long Bones of Young Rats: A Model for Studying Cancer Chemotherapy-Induced Bone Growth Defects in Children

Chiaming Fan et al.

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2011)

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Article Oncology

Ewing sarcoma cells express RANKL and support osteoclastogenesis

Richard Taylor et al.

JOURNAL OF PATHOLOGY (2011)

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Article Multidisciplinary Sciences

Clinical-Grade Generation of Active NK Cells from Cord Blood Hematopoietic Progenitor Cells for Immunotherapy Using a Closed-System Culture Process

Jan Spanholtz et al.

PLOS ONE (2011)

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Article Multidisciplinary Sciences

Irradiation induces bone injury by damaging bone marrow microenvironment for stem cells

Xu Cao et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

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Article Hematology

NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects

Janelle A. Olson et al.

BLOOD (2010)

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Article Oncology

Cytotoxicity of Activated Natural Killer Cells against Pediatric Solid Tumors

Duck Cho et al.

CLINICAL CANCER RESEARCH (2010)

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Article Oncology

HIGH-DOSE BUSULFAN AND MELPHALAN AS CONDITIONING REGIMEN FOR AUTOLOGOUS PERIPHERAL BLOOD PROGENITOR CELL TRANSPLANTATION IN HIGH-RISK EWING SARCOMA PATIENTS: A Long-Term Follow-Up Single-Center Study

Miguel A. Diaz et al.

PEDIATRIC HEMATOLOGY AND ONCOLOGY (2010)

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Article Hematology

ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype

Alessandra Soriani et al.

BLOOD (2009)

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Article Hematology

Human embryonic stem cells differentiate into a homogeneous population of natural killer cells with potent in vivo antitumor activity

Petter S. Woll et al.

BLOOD (2009)

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Article Oncology

Ewing Sarcoma Demonstrates Racial Disparities in Incidence-related and Sex-related Differences in Outcome An Analysis of 1631 Cases From the SEER Database, 1973-2005

Muhammad U. Jawad et al.

CANCER (2009)

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Article Oncology

Osteosarcoma Incidence and Survival Rates From 1973 to 2004 Data From the Surveillance, Epidemiology, and End Results Program

Lisa Mirabello et al.

CANCER (2009)

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Article Oncology

Identification of Cancer Stem Cells in Ewing's Sarcoma

Mario-Luca Suva et al.

CANCER RESEARCH (2009)

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Article Oncology

A high proportion of bone marrow T cells with regulatory phenotype (CD4+CD25hiFoxP3+) in Ewing sarcoma patients is associated with metastatic disease

Peter Brinkrolf et al.

INTERNATIONAL JOURNAL OF CANCER (2009)

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Review Biophysics

Growth plate mechanics and mechanobiology. A survey of present understanding

Isabelle Villemure et al.

JOURNAL OF BIOMECHANICS (2009)

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Inhibition of the Insulin-like Growth Factor-1 Receptor (IGF1R) Tyrosine Kinase as a Novel Cancer Therapy Approach

Rongshi Li et al.

JOURNAL OF MEDICINAL CHEMISTRY (2009)

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Article Oncology

Bone Marrow-Derived Stem Cells and Radiation Response

Joel S. Greenberger et al.

SEMINARS IN RADIATION ONCOLOGY (2009)

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Article Urology & Nephrology

Normal Bone Anatomy and Physiology

Bart Clarke

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)

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Review Endocrinology & Metabolism

Growth hormone, insulin-like growth factors, and the skeleton

Andrea Giustina et al.

ENDOCRINE REVIEWS (2008)

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Meeting Abstract Hematology

KIR incompatible NK cells effectively lyse osteosarcoma cells

David C. Delgado et al.

BLOOD (2007)

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Article Biology

Radiation-induced reduction of osteoblast differentiation in C2C12 cells

Tomonori Sakurai et al.

JOURNAL OF RADIATION RESEARCH (2007)

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Review Oncology

Primary bone osteosarcoma in the pediatric age: State of the art

Alessandra Longhi et al.

CANCER TREATMENT REVIEWS (2006)

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Article Oncology

A phase I clinical trial of the hu14.18-IL2 (EMD 273063) as a treatment for children with refractory or recurrent neuroblastoma and melanoma: A study of the Children's Oncology Group

KL Osenga et al.

CLINICAL CANCER RESEARCH (2006)

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Article Medicine, General & Internal

Risk of pelvic fractures in older women following pelvic irradiation

NN Baxter et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)

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Article Endocrinology & Metabolism

Ionizing radiation sensitizes bone cells to apoptosis

KH Szymczyk et al.

BONE (2004)

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Article Oncology

Neoadjuvant chemotherapy for high-grade central osteosarcoma of the extremity - Histologic response to preoperative chemotherapy correlates with histologic subtype of the tumor

G Bacci et al.

CANCER (2003)

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Article Biochemistry & Molecular Biology

α4 integrin increases anoikis of human osteosarcoma cells

RAW Marco et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2003)

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Article Medicine, General & Internal

Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone

HE Grier et al.

NEW ENGLAND JOURNAL OF MEDICINE (2003)

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Article Hematology

Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcγRIIIa gene

G Cartron et al.

BLOOD (2002)

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Article Immunology

Spatial organization of signal transduction molecules in the NK cell immune synapses during MHC class I-regulated noncytolytic and cytolytic interactions

YM Vyas et al.

JOURNAL OF IMMUNOLOGY (2001)

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Article Medicine, General & Internal

Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population

K Imai et al.

LANCET (2000)

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Article Immunology

Tumor necrosis factor α stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction

K Kobayashi et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2000)

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