Related references
Note: Only part of the references are listed.Monoclonal Antibody Engineering and Design to Modulate FcRn Activities: A Comprehensive Review
Yanis Ramdani et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Antibody Fc engineering for enhanced neonatal Fc receptor binding and prolonged circulation half-life
Brian C. Mackness et al.
MABS (2019)
Insights into the IgG heavy chain engineering patent landscape as applied to IgG4 antibody development
Christophe Dumet et al.
MABS (2019)
Pharmacokinetics of monoclonal antibodies and Fc-fusion proteins
Liming Liu
PROTEIN & CELL (2018)
A minimal physiologically based pharmacokinetic model to investigate FcRn-mediated monoclonal antibody salvage: Effects of Kon, Koff, endosome trafficking, and animal species
Brian M. Maas et al.
MABS (2018)
Targeting FcRn to Generate Antibody-Based Therapeutics
E. Sally Ward et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2018)
Protein-protein interactions: scoring schemes and binding affinity
M. Michael Gromiha et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2017)
Conformational Destabilization of Immunoglobulin G Increases the Low pH Binding Affinity with the Neonatal Fc Receptor
Benjamin T. Walters et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
IgG1 Allotypes Influence the Pharmacokinetics of Therapeutic Monoclonal Antibodies through FcRn Binding
David Ternant et al.
JOURNAL OF IMMUNOLOGY (2016)
Selection of IgG variants with increased FcRn binding using random and directed mutagenesis: impact on effector functions
Celine Monnet et al.
FRONTIERS IN IMMUNOLOGY (2015)
pH-dependent Binding Engineering Reveals an FcRn Affinity Threshold That Governs IgG Recycling
M. Jack Borrok et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Enhanced neonatal Fc receptor function improves protection against primate SHIV infection
Sung-Youl Ko et al.
NATURE (2014)
IgG subclasses and allotypes: from structure to effector functions
Gestur Vidarsson et al.
FRONTIERS IN IMMUNOLOGY (2014)
Binding structures and energies of the human neonatal Fc receptor with human Fc and its mutants by molecular modeling and dynamics simulations
Xiaoqin Huang et al.
MOLECULAR BIOSYSTEMS (2013)
Engineered Monoclonal Antibody with Novel Antigen-Sweeping Activity In Vivo
Tomoyuki Igawa et al.
PLOS ONE (2013)
pH-selective mutagenesis of protein-protein interfaces: In silico design of therapeutic antibodies with prolonged half-life
Velin Z. Spassov et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2013)
Are Scoring Functions in Protein-Protein Docking Ready to Predict Interactomes? Clues from a Novel Binding Affinity Benchmark (vol 9, pg 2216, 2010)
Panagiotis L. Kastritis et al.
JOURNAL OF PROTEOME RESEARCH (2011)
Pharmacokinetics of Humanized Monoclonal Anti-Tumor Necrosis Factor-α Antibody and Its Neonatal Fc Receptor Variants in Mice and Cynomolgus Monkeys
Rong Deng et al.
DRUG METABOLISM AND DISPOSITION (2010)
Enhanced antibody half-life improves in vivo activity
Jonathan Zalevsky et al.
NATURE BIOTECHNOLOGY (2010)
Calculation of the free energy of association for protein complexes
Nancy Horton et al.
PROTEIN SCIENCE (2010)
Engineering Human IgG1 Affinity to Human Neonatal Fc Receptor: Impact of Affinity Improvement on Pharmacokinetics in Primates
Yik Andy Yeung et al.
JOURNAL OF IMMUNOLOGY (2009)
ZRANK: Reranking protein docking predictions with an optimized energy function
Brian Pierce et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2007)
Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease
Stefka B. Petkova et al.
INTERNATIONAL IMMUNOLOGY (2006)
Properties of human IgG1s engineered for enhanced binding to the neonatal Fc receptor (FcRn)
William F. Dall'Acqua et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The FoldX web server: an online force field
J Schymkowitz et al.
NUCLEIC ACIDS RESEARCH (2005)
Predicting changes in the stability of proteins and protein complexes: A study of more than 1000 mutations
R Guerois et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Further development and validation of empirical scoring functions for structure-based binding affinity prediction
RX Wang et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2002)
High resolution mapping of the binding site on human IgG1 for FcγRI, FcγRII, FcγRIII, and FcRn and design of IgG1 variants with improved binding to the FcγR
RL Shields et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Share Paper
