Flavonoids as Promising Natural Compounds in the Prevention and Treatment of Selected Skin Diseases

Phytochemicals represent a large and diverse group of naturally occurring compounds, bioactive nutrients, or phytonutrients produced by plants, widely found in fruits, vegetables, whole grains products, legumes, beans, herbs, seeds, nuts, tea, and dark chocolate. They are classified according to their chemical structures and functional properties. Flavonoids belong to the phenolic class of phytochemicals with potential solid pharmacological effects as modulators of multiple signal transduction pathways. Their beneficial effect on the human body is associated with their antioxidant, anti-inflammatory, antimutagenic, and anticarcinogenic properties. Flavonoids are also widely used in various nutritional, pharmaceutical, medical, and cosmetic applications. In our review, we discuss the positive effect of flavonoids on chronic skin diseases such as vitiligo, psoriasis, acne, and atopic dermatitis.

Automated summary

Phytochemicals, including flavonoids, are naturally occurring compounds found in plants and have various beneficial effects on the human body. Flavonoids, belonging to the phenolic class, have potent pharmacological effects as modulators of multiple signal transduction pathways. They exhibit antioxidant, anti-inflammatory, antimutagenic, and anticarcinogenic properties. Flavonoids are widely used in nutrition, pharmaceuticals, medicine, and cosmetics. In this review, we discuss the positive impact of flavonoids on chronic skin diseases such as vitiligo, psoriasis, acne, and atopic dermatitis.