4.7 Article

Chronic Exposure to High Fat Diet Affects the Synaptic Transmission That Regulates the Dopamine Release in the Nucleus Accumbens of Adolescent Male Rats

Related references

Note: Only part of the references are listed.
Article Neurosciences

Interleukin-6 and tumor necrosis factor-α attenuate dopamine release in mice fed a high-fat diet, but not medium or low-fat diets

H. A. Emmons et al.

Summary: Chronic low-grade inflammation can directly affect dopamine neurotransmission in the brain, and dietary fat consumption increases neural responsiveness to cytokines. This finding may provide insights into the comorbidity between diet-induced obesity and depression or other mood disorders.

NUTRITIONAL NEUROSCIENCE (2023)

Review Biochemistry & Molecular Biology

Obesity and the Brain

Jacek Karczewski et al.

Summary: Innate and adaptive immunity play vital roles in neurodevelopment and CNS homeostasis. Overactivation of the immune system increases brain vulnerability and the risk of neuropsychiatric disorders. Obesity and gut dysbiosis are important factors affecting microglial function in later life.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Biochemistry & Molecular Biology

Effects of Early Life Exposure to Sex Hormones on Neurochemical and Behavioral Responses to Psychostimulants in Adulthood: Implications in Drug Addiction

Maximiliano Elgueta-Reyes et al.

Summary: Early life exposure to sex hormones has long-lasting effects on brain areas involved in regulating locomotor and motivation behaviors. This study demonstrates that neonatal exposure to sex hormones alters the brain dopamine system and affects behavioral and neurochemical responses to amphetamine and methylphenidate.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)

Article Neurosciences

Estrogen receptor alpha, G-protein coupled estrogen receptor 1, and aromatase: Developmental, sex, and region-specific differences across the rat caudate-putamen, nucleus accumbens core and shell

Amanda A. Krentzel et al.

Summary: Sex steroid hormones such as estradiol regulate neuronal function through estrogen receptors and aromatase. These proteins are expressed in the striatal brain regions, playing a role in various functions and disorders with sex differences. The developmental period exerts critical sex-specific influences on the striatal cellular estrogenic mechanisms, showing differences in ER alpha, GPER1, and aromatase expression based on sex, region, and age.

JOURNAL OF COMPARATIVE NEUROLOGY (2021)

Review Nutrition & Dietetics

Does Modern Lifestyle Favor Neuroimmunometabolic Changes? A Path to Obesity

Camila Guazzelli Marques et al.

Summary: Modern lifestyle factors such as physical inactivity, Western diet, and poor sleep quality play a key role in positive energy balance, leading to adipose tissue hypertrophy and dysfunction. The interaction between lifestyle factors and tissue metabolic dysfunction can increase chronic systemic inflammation, resulting in insulin resistance and other metabolic disorders.

FRONTIERS IN NUTRITION (2021)

Article Endocrinology & Metabolism

Bingeing on High-Fat Food Enhances Evoked Dopamine Release and Reduces Dopamine Uptake in the Nucleus Accumbens

Sara R. Jones et al.

Summary: Binge-eating disorder disrupts dopamine neuron function by altering dopamine transporter activity. This study found that acute low-dose amphetamine can restore dopamine transporter function, but does not reduce dopamine release to normal levels caused by high-fat bingeing. This research suggests that presynaptic changes should be considered in the use of amphetamine-like dopamine releasers for treating BED.

OBESITY (2021)

Review Biochemistry & Molecular Biology

NLRP3 Inflammasome: Potential Role in Obesity Related Low-Grade Inflammation and Insulin Resistance in Skeletal Muscle

Gonzalo Jorquera et al.

Summary: Low-grade inflammation is crucial for the development of insulin resistance in type 2 diabetes, with NLRP3 inflammasome playing a potential pathological role in glucose handling in skeletal muscle of obese individuals. NLRP3 inhibitors may have therapeutic use in obesity-related metabolic alterations.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Nutrition & Dietetics

Replacing a Palatable High-Fat Diet with a Low-Fat Alternative Heightens κ-Opioid Receptor Control over Nucleus Accumbens Dopamine

Conner W. Wallace et al.

Summary: The study found that activation of kappa-opioid receptors (KORs) reduces dopamine levels in the nucleus accumbens and increases food-related anxiety, which may subsequently promote cravings for high-fat and high-sugar palatable foods during dietary weight loss interventions.

NUTRIENTS (2021)

Review Biochemistry & Molecular Biology

The NLRP3 inflammasome regulates adipose tissue metabolism

Nicole G. Barra et al.

BIOCHEMICAL JOURNAL (2020)

Article Neurosciences

Interactions between insulin and diet on striatal dopamine uptake kinetics in rodent brain slices

Jyoti C. Patel et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2019)

Review Neurosciences

Diversity in the lateral hypothalamic input to the ventral tegmental area

Nathan Godfrey et al.

NEUROPHARMACOLOGY (2019)

Review Biochemistry & Molecular Biology

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

Nathan Kelley et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Neurosciences

Ventral Pallidum Is the Primary Target for Accumbens D1 Projections Driving Cocaine Seeking

Thibaut R. Pardo-Garcia et al.

JOURNAL OF NEUROSCIENCE (2019)

Review Neurosciences

Feeding circuit development and early-life influences on future feeding behaviour

Lori M. Zeltser

NATURE REVIEWS NEUROSCIENCE (2018)

Article Biochemistry & Molecular Biology

Cafeteria diet induces neuroplastic modifications in the nucleus accumbens mediated by microglia activation

Miriam Gutierrez-Martos et al.

ADDICTION BIOLOGY (2018)

Review Endocrinology & Metabolism

Current role of the NLRP3 inflammasome on obesity and insulin resistance: A systematic review

Jakeline Rheinheimer et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2017)

Review Endocrinology & Metabolism

Neural Circuit Mechanisms Underlying Emotional Regulation of Homeostatic Feeding

Patrick Sweeney et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2017)

Article Endocrinology & Metabolism

Food for Thought: Reward Mechanisms and Hedonic Overeating in Obesity

Phong Ching Lee et al.

CURRENT OBESITY REPORTS (2017)

Article Substance Abuse

Nalmefene Prevents Alcohol-Induced Neuroinflammation and Alcohol Drinking Preference in Adolescent Female Mice: Role of TLR4

Jorge Montesinos et al.

ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2017)

Article Cell Biology

Pharmacotherapy for the treatment of obesity

Arianne N. Sweeting et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2015)

Article Biochemistry & Molecular Biology

Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis

Antonio Giordano et al.

JOURNAL OF LIPID RESEARCH (2013)

Article Neurosciences

Dopamine D-2 Receptors Regulate Collateral Inhibition between Striatal Medium Spiny Neurons

Rupa R. Lalchandani et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Multidisciplinary Sciences

Prolonged High Fat Diet Reduces Dopamine Reuptake without Altering DAT Gene Expression

Jackson J. Cone et al.

PLOS ONE (2013)

Article Neurosciences

Regulation of prefrontal excitatory neurotransmission by dopamine in the nucleus accumbens core

Wengang Wang et al.

JOURNAL OF PHYSIOLOGY-LONDON (2012)

Review Behavioral Sciences

Hypocretin/orexin regulation of dopamine signaling: implications for reward and reinforcement mechanisms

Erin S. Calipari et al.

FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2012)

Article Biochemical Research Methods

Demon Voltammetry and Analysis software: Analysis of cocaine-induced alterations in dopamine signaling using multiple kinetic measures

Jordan T. Yorgason et al.

JOURNAL OF NEUROSCIENCE METHODS (2011)

Review Endocrinology & Metabolism

AGE restriction in diabetes mellitus: a paradigm shift

Helen Vlassara et al.

NATURE REVIEWS ENDOCRINOLOGY (2011)

Review Neurosciences

Neurocircuitry of Addiction

George F. Koob et al.

NEUROPSYCHOPHARMACOLOGY (2010)

Article Psychology, Biological

Role of orexin/hypocretin in reward-seeking and addiction: Implications for obesity

Angie M. Cason et al.

PHYSIOLOGY & BEHAVIOR (2010)

Review Multidisciplinary Sciences

The NLRP3 Inflammasome: A Sensor for Metabolic Danger?

Kate Schroder et al.

SCIENCE (2010)

Editorial Material Clinical Neurology

Large-scale trial suggests ethosuximide as best treatment for absence epilepsy

[Anonymous]

FUTURE NEUROLOGY (2010)

Article Neurosciences

Dichotomous Anatomical Properties of Adult Striatal Medium Spiny Neurons

Tracy S. Gertler et al.

JOURNAL OF NEUROSCIENCE (2008)

Article Neurosciences

Afferents to the orexin neurons of the rat brain

K Yoshida et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2006)

Article Psychiatry

The neural basis of addiction: A pathology of motivation and choice

PW Kalivas et al.

AMERICAN JOURNAL OF PSYCHIATRY (2005)

Article Physiology

Oral sucrose stimulation increases accumbens dopamine in the rat

A Hajnal et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2004)