4.7 Article

Antitumoral and Immunogenic Capacity of β-D-Glucose-Reduced Silver Nanoparticles in Breast Cancer

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Bactericide Activity of Cellulose Acetate/Silver Nanoparticles Asymmetric Membranes: Surfaces and Porous Structures Role

Ana Sofia Figueiredo et al.

Summary: The antibacterial properties of cellulose acetate/silver nanoparticles (AgNP) ultrafiltration membranes were studied and the results showed that the distinct features of each side of the membranes, the active and porous layers surfaces, played a role in the antibacterial activity. The composition and structure of the membranes affected the accessibility of the silver to Escherichia coli (E. coli), leading to different levels of growth inhibition. The findings suggest that the membrane design and silver distribution can be optimized to enhance the antibacterial performance.

MEMBRANES (2023)

Article Toxicology

Silver nanoparticles induce a non-immunogenic tumor cell death

Maritza Roxana Garcia Garcia et al.

Summary: This study evaluated the ability of silver nanoparticles (AgNP) to induce immunogenic cell death (ICD) and their anti-cancer effects in vitro and in vivo. The results showed that AgNP had anti-proliferative effects on CT26 and MCA205 cell lines and could release calreticulin. However, immunization with AgNP-treated tumor cell debris failed to induce a protective immune response in vivo. Further research is needed to explore the combination of AgNP with other ICD inducers to enhance their anti-tumor effect in vivo.

JOURNAL OF IMMUNOTOXICOLOGY (2023)

Article Chemistry, Physical

Immunogenic cell death effects induced by doxorubicin improved chemo-immunotherapy via restoration of granzyme B activity

Tao Huang et al.

Summary: This study develops a targeted nanomedicine for breast cancer chemo-immunotherapy, which can induce immunogenic cell death (ICD) to kill cancer cells and stimulate antitumor immune response. The nanomedicine also competitively relieves the inhibition of serpinb9 (Sb9) to granzyme B (GrB), enhancing the combined antitumor effect.

NANO RESEARCH (2023)

Article Chemistry, Multidisciplinary

Programing Immunogenic Cell Death in Breast Tumors with Designer DNA Frameworks

Tian Tian et al.

Summary: In this study, a multifunctional tetrahedral DNA framework (TDF) was developed as a drug carrier to recruit chemotherapeutants and trigger immunogenic cell death (ICD) effects, which could turn tumors from cold to hot to boost the efficacy of antitumor immunotherapy.

JACS AU (2023)

Article Oncology

The Incidence of Breast Cancer Recurrence 10-32 Years After Primary Diagnosis

Rikke Norgaard Pedersen et al.

Summary: Research shows that there is still a risk of breast cancer recurrence up to 32 years after the initial diagnosis. Tumor size larger than 20 mm, lymph node-positive disease, and estrogen receptor-positive tumors are associated with increased risk of late breast cancer recurrence. Women with these characteristics may require extended surveillance, more aggressive treatment, or new therapy approaches.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2022)

Review Immunology

Immunogenic cell stress and death

Guido Kroemer et al.

Summary: Immunogenic cell death (ICD) plays an important role in therapy and disease, as dying mammalian cells release signals that interact with the host to determine the immunological correlates of cellular stress and death. ICD is crucial in immunosurveillance and is related to strategies evolved by pathogens and cancer cells. Additionally, normal cell death can also initiate antigen-specific immune responses.

NATURE IMMUNOLOGY (2022)

Review Cell Biology

Cell cycle control in cancer

Helen K. Matthews et al.

Summary: This review highlights the importance of cell cycle regulation in preventing genetic errors and cell proliferation, and how disruption of these mechanisms is associated with cancer development. Cancer arises from continuous cell division and evasion of cell cycle control mechanisms.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2022)

Article Materials Science, Paper & Wood

Preparation and shape change of silver nanoparticles (AgNPs) loaded on the dialdehyde cellulose by in-situ synthesis method

Peng Du et al.

Summary: This study prepared antibacterial materials by loading silver nanoparticles on dialdehyde cellulose using an in-situ synthesis method. The silver nanoparticles were observed to be uniformly distributed on the cellulose surface without obvious aggregation. The antibacterial properties of the materials showed significant inhibition zones against both Gram-negative and Gram-positive bacteria.

CELLULOSE (2022)

Article Genetics & Heredity

Immunogenic cell death-related classifications in breast cancer identify precise immunotherapy biomarkers and enable prognostic stratification

Xue Wang et al.

Summary: This study discovers that the subtyping based on immunogenic cell death (ICD) can be used to evaluate the prognosis and clinical outcomes of immunotherapy in breast cancer (BC) patients. The constructed ICD risk and prognosis model can effectively predict the survival rate of BC patients and is negatively correlated with the immune microenvironment and clinical stage.

FRONTIERS IN GENETICS (2022)

Article Genetics & Heredity

An immunogenic cell death-associated classification predictions are important for breast invasive carcinoma prognosis and immunotherapy

Xinghe Liao et al.

Summary: This study investigates the role of immunogenic cell death (ICD) in modifying the tumor immune microenvironment and develops a novel ICD-associated prognostic model for predicting the survival of patients with breast invasive carcinomas (BRCA).

FRONTIERS IN GENETICS (2022)

Article Toxicology

The mechanism of cell death induced by silver nanoparticles is distinct from silver cations

Monica M. Rohde et al.

Summary: The study identified distinct responses of cells to AgNPs and Ag+. AgNPs induce cell death through lipid peroxidation leading to proteotoxicity and necrotic cell death, while Ag+ triggers oxidative stress and apoptotic cell death by increasing H2O2 levels. The mechanism by which AgNPs kill mammalian cells was found to be independent of the contribution of Ag+ released in extracellular media.

PARTICLE AND FIBRE TOXICOLOGY (2021)

Review Pathology

Molecular Classification of Breast Cancer

Julia Y. S. Tsang et al.

ADVANCES IN ANATOMIC PATHOLOGY (2020)

Review Oncology

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

Lorenzo Galluzzi et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2020)

Review Oncology

Targeting immunogenic cell death in cancer

Asma Ahmed et al.

MOLECULAR ONCOLOGY (2020)

Review Medicine, General & Internal

Breast Cancer Treatment A Review

Adrienne G. Waks et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2019)

Article Biochemistry & Molecular Biology

Synthesis of silver nanoparticles (Ag NPs) for anticancer activities (MCF 7 breast and A549 lung cell lines) of the crude extract of Syzygium aromaticum

K. Venugopal et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2017)

Article Toxicology

Glucose capped silver nanoparticles induce cell cycle arrest in HeLa cells

Elisa Panzarini et al.

TOXICOLOGY IN VITRO (2017)

Article Engineering, Electrical & Electronic

Structural, thermal, zeta potential and electrical properties of disaccharide reduced silver nanoparticles

Suman Singh et al.

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS (2014)

Article Biotechnology & Applied Microbiology

Cytotoxicity of Biologically Synthesized Silver Nanoparticles in MDA-MB-231 Human Breast Cancer Cells

Sangiliyandi Gurunathan et al.

BIOMED RESEARCH INTERNATIONAL (2013)

Article Oncology

Antitumor activity of colloidal silver on MCF-7 human breast cancer cells

Moises A. Franco-Molina et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2010)