☆ 4.5 Review

Integrity of randomized clinical trials: Performance of integrity tests and checklists requires assessment

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (2023)

Related references

Note: Only part of the references are listed.

Article Obstetrics & Gynecology

Concerns about Data Integrity of 22 Randomized Controlled Trials in Women's Health

Yizhen Liu et al.

Summary: The analysis of 22 RCTs by Dr. Maged suggests potential data integrity issues, and it is recommended that journals investigate according to the guidelines of the Committee on Publication Ethics. The procedures demonstrated in this paper may help assess data integrity for future attempts to verify the authenticity of published RCTs.

AMERICAN JOURNAL OF PERINATOLOGY (2023)

Add to Collection

Article Obstetrics & Gynecology

International multi-stakeholder consensus statement on clinical trial integrity

Khalid Saeed Khan

Summary: A set of statements for RCT integrity was prepared through a multi-stakeholder consensus that involved stakeholders from multiple countries and disciplines, evidence synthesis of systematic reviews, and a modified Delphi survey. The final consensus included 81 statements covering various aspects of the RCT life cycle. Implementation of this consensus statement is expected to enhance RCT integrity.

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2023)

Add to Collection

Review Obstetrics & Gynecology

Research integrity in randomized clinical trials: A scoping umbrella review

Maria Nunez-Nunez et al.

Summary: This study provides an overarching overview of the research integrity in randomized clinical trials (RCTs). It reveals the presence of low-quality reviews and identifies integrity issues and gaps across the RCT lifecycle. Multistakeholder consensus is required to develop specific RCT integrity standards and improve the trustworthiness of RCTs.

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (2023)

Add to Collection

Editorial Material Information Science & Library Science

Fortification of retraction notices to improve their transparency and usefulness

Jaime A. Teixeira da Silva et al.

LEARNED PUBLISHING (2022)

Add to Collection

Article Multidisciplinary Sciences

Prevalence of questionable research practices, research misconduct and their potential explanatory factors: A survey among academic researchers in The Netherlands

Gowri Gopalakrishna et al.

Summary: The prevalence of research misconduct and questionable research practices among academic researchers, as well as their associations with explanatory factors, has not been adequately studied. This study conducted a national survey to investigate the prevalence of fabrication, falsification, and various questionable research practices (QRPs) among academic researchers in the Netherlands. The study identified several explanatory factors associated with engaging in research misconduct and QRPs, including academic rank, gender, adherence to scientific norms, perceived likelihood of detection, and publication pressure. The findings suggest the need for greater emphasis on scientific norm adherence, strengthening the role of reviewers, and addressing the publish or perish incentive system to promote research integrity.

PLOS ONE (2022)

Add to Collection

Review Health Care Sciences & Services

Regulatory Frameworks for Clinical Trial Data Sharing: Scoping Review

Nachiket Gudi et al.

Summary: Although there is recognition of the scientific value of data sharing from clinical trials, there are various limitations and challenges in implementing data sharing practices. This review highlights the need for a pragmatic data-sharing mechanism to improve research and innovations, and calls for the development of flexible yet comprehensive data-sharing policies. It also emphasizes the importance of institutional mechanisms and policy interventions in facilitating data sharing, particularly in low- and middle-income countries.

JOURNAL OF MEDICAL INTERNET RESEARCH (2022)

Add to Collection

Article Oncology

Retraction and republication—Stereotactic body radiotherapy plus pembrolizumab and trametinib versus stereotactic body radiotherapy plus gemcitabine for locally recurrent pancreatic cancer after surgical resection: an open-label, randomised, controlled, phase 2 trial

The Editors of The Lancet Oncology

LANCET ONCOLOGY (2022)

Add to Collection

Letter Obstetrics & Gynecology

Integrity culture is underpinned by education, not post-submission dishonesty assessments

Khalid S. Khan

REPRODUCTIVE BIOMEDICINE ONLINE (2022)

Add to Collection

Editorial Material Obstetrics & Gynecology

Assuring integrity in Obstetrics and Gynecology research

Michael Geary et al.

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (2022)

Add to Collection

Article Multidisciplinary Sciences

Dynamics of cross-platform attention to retracted papers

Hao Peng et al.

Summary: Retracted papers often circulate widely online before their official retraction, which can harm the scientific community and the public. This study shows that retracted papers receive more attention not only on social media but also on curated platforms, amplifying their negative impact. Additionally, posts on Twitter tend to express more criticism about retracted papers, suggesting the presence of factual information about problematic papers.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2022)

Add to Collection

Letter Obstetrics & Gynecology

Letter to the Editor: Research and consensus is required concerning integrity of randomized clinical trials

Khalid S. Khan et al.

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (2022)

Add to Collection

Article Anesthesiology

False individual patient data and zombie randomised controlled trials submitted toAnaesthesia

J. B. Carlisle

Summary: The author analyzed the baseline summary data of randomized controlled trials submitted to Anaesthesia from 2017 to 2020, identifying 14% of trials containing false data and categorizing 8% as 'zombie'. The analysis showed that individual patient data increased detection of false data and categorization of trials as 'zombie'. China, South Korea, India, Japan, and Egypt were the top five countries submitting trials, with China having the highest proportion.

ANAESTHESIA (2021)

Add to Collection

Editorial Material Multidisciplinary Sciences

Want research integrity? Stop the blame game

Malcolm Macleod

NATURE (2021)

Add to Collection

Article Obstetrics & Gynecology

Assessing Research Misconduct in Randomized Controlled Trials

Khalid S. Khan

OBSTETRICS AND GYNECOLOGY (2021)

Add to Collection

Article Health Care Sciences & Services

Participant withdrawals were unusually distributed in randomized trials with integrity concerns: a statistical investigation

Mark J. Bolland et al.

Summary: Comparing observed and expected distributions of trial withdrawals in RCTs can be a useful technique for assessing publication integrity, with significant differences found in RCTs with concerns about publication integrity. Control RCTs showed consistent results, while RCTs with publication integrity concerns had striking differences in withdrawal distributions.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2021)

Add to Collection

Article Obstetrics & Gynecology

Protecting data integrity in reproductive medicine

Bart CJM Fauser

REPRODUCTIVE BIOMEDICINE ONLINE (2021)

Add to Collection

Article Health Care Sciences & Services

Estimating the sample mean and standard deviation from order statistics and sample size in meta-analysis

Siyu Cai et al.

Summary: Researchers have proposed a new method using maximum likelihood estimation and Box-Cox transformation to deal with the lack of standard deviations in medical studies. Through simulation studies and real data analysis, it was found that this method generally outperforms existing methods in estimation accuracy.

STATISTICAL METHODS IN MEDICAL RESEARCH (2021)

Add to Collection

Review Multidisciplinary Sciences

Systematic review and meta-analyses of studies analysing instructions to authors from 1987 to 2017

Mario Malicki et al.

Summary: The study found that requirements regarding authorship, conflict of interests, data sharing, funding disclosure, and ethics approval declaration in scholarly journals vary greatly over time, among journals, and across disciplines.

NATURE COMMUNICATIONS (2021)

Add to Collection

Article Medicine, General & Internal

Evaluation of Data Sharing After Implementation of the International Committee of Medical Journal Editors Data Sharing Statement Requirement

Valentin Danchev et al.

Summary: The study evaluated the implementation of the ICMJE data sharing statement requirement in three leading medical journals, finding a significant gap between declared and actual sharing of clinical trial data, despite a high rate of data sharing declaration.

JAMA NETWORK OPEN (2021)

Add to Collection

Article Health Care Sciences & Services

Identical summary statistics were uncommon in randomized trials and cohort studies

Mark J. Bolland et al.

Summary: The study suggests that the probability of identical summary statistics in different RCTs or clinical cohorts is low, unless the variables are rounded to 1 significant figure. Furthermore, the high proportion of identical summary statistics in clinical cohorts with publication integrity concerns is improbable based on simulations and comparisons to control datasets.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2021)

Add to Collection

Letter Health Care Sciences & Services

Comment on Khan: 'Flawed use of post publication data fabrication tests'. Research misconduct tests: putting patients' interests first

Khalid Saeed Khan

JOURNAL OF CLINICAL EPIDEMIOLOGY (2021)

Add to Collection

Review Health Care Sciences & Services

Methods to assess research misconduct in health-related research: A scoping review

Esmee M. Bordewijk et al.

Summary: This study provides an overview of methods to investigate research misconduct in health-related research. While measures against textual plagiarism are well implemented, tools for other forms of research misconduct are lacking standardization and formal validation, calling for further development of automatic tools and routine validation of these methods.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2021)

Add to Collection

Article Obstetrics & Gynecology

Assessing Research Misconduct in Randomized Controlled Trials

Wentao Li et al.

Summary: Randomized controlled trials are crucial in evidence-based medicine, but compromised data integrity and research misconduct pose risks to patients and undermine the authority of this scientific tool. There is a need for better methods to detect and prevent research misconduct, as well as improved mechanisms for investigating data manipulation and prioritizing patient and reader interests over trial authors and institutions.

OBSTETRICS AND GYNECOLOGY (2021)

Add to Collection

Editorial Material Multidisciplinary Sciences

Check for publication integrity before misconduct

Andrew Grey et al.

NATURE (2020)

Add to Collection

Editorial Material Neurosciences

No raw data, no science: another possible source of the reproducibility crisis

Tsuyoshi Miyakawa

MOLECULAR BRAIN (2020)

Add to Collection

Editorial Material Obstetrics & Gynecology

Data integrity of 35 randomised controlled trials in women' health

Esmee M. Bordewijk et al.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2020)

Add to Collection

Editorial Material Obstetrics & Gynecology

Fabricated data - should we quarantine? A novel tool for risk assessment is proposed

Janesh K. Gupta

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY (2020)

Add to Collection

Letter Anesthesiology

Empirically generated reference proportions for baseline p values from rounded summary statistics

M. J. Bolland et al.

ANAESTHESIA (2020)

Add to Collection

Review Obstetrics & Gynecology

Integrity of randomized controlled trials: challenges and solutions

Wentao Li et al.

FERTILITY AND STERILITY (2020)

Add to Collection

Article Health Care Sciences & Services

Misconduct as the main cause for retraction. A descriptive study of retracted publications and their authors

Isabel Campos-Varela et al.

GACETA SANITARIA (2019)

Add to Collection

Article Obstetrics & Gynecology

Plagiarism and data falsification are the most common reasons for retracted publications in obstetrics and gynaecology

L. M. Chambers et al.

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2019)

Add to Collection

Article Health Care Sciences & Services

Rounding, but not randomization method, non-normality, or correlation, affected baseline P-value distributions in randomized trials

Mark J. Bolland et al.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2019)

Add to Collection

Article Rheumatology

Instrument Selection Using the OMERACT Filter 2.1: The OMERACT Methodology

Dorcas E. Beaton et al.

JOURNAL OF RHEUMATOLOGY (2019)

Add to Collection

Article Rheumatology

OMERACT Filter 2.1: Elaboration of the Conceptual Framework for Outcome Measurement in Health Intervention Studies

Maarten Boers et al.

JOURNAL OF RHEUMATOLOGY (2019)

Add to Collection

Editorial Material Medicine, General & Internal

New Guidelines for Statistical Reporting in the Journal

David Harrington et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Add to Collection

Review Multidisciplinary Sciences

Diagnostic test evaluation methodology: A systematic review of methods employed to evaluate diagnostic tests in the absence of gold standard - An update

Chinyereugo M. Umemneku Chikere et al.

PLOS ONE (2019)

Add to Collection

Article Ethics

Openness in Big Data and Data Repositories: The Application of an Ethics Framework for Big Data in Health and Research

Vicki Xafis et al.

ASIAN BIOETHICS REVIEW (2019)

Add to Collection

Retraction Medicine, General & Internal

撤稿声明: Retraction and Republication: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. N Engl J Med 2013;368:1279-90 (Retraction of Vol 368, Pg 1279, 2013)

Ramon Estruch et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Add to Collection

Article Medicine, General & Internal

Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts

R. Estruch et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Add to Collection

Editorial Material Medicine, General & Internal

Scientific Misconduct and Medical Journals

Howard Bauchner et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2018)

Add to Collection

Review Public, Environmental & Occupational Health

Best Practices for Developing and Validating Scales for Health,Social, and Behavioral Research:A Primer

Godfred O. Boateng et al.

FRONTIERS IN PUBLIC HEALTH (2018)

Add to Collection

Letter Anesthesiology

Seeking and reporting apparent research misconduct: errors and integrity

E. D. Kharasch et al.

ANAESTHESIA (2018)

Add to Collection

Editorial Material Clinical Neurology

To catch a crook, you might try statistics

Gary R. Cutter

NATURE REVIEWS NEUROLOGY (2017)

Add to Collection

Editorial Material Medicine, General & Internal

Correcting the Medical Literature: To Err Is Human, to Correct Divine

Stacy Christiansen et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)

Add to Collection

Editorial Material Medicine, General & Internal

Data Sharing Statements for Clinical Trials A Requirement of the International Committee of Medical Journal Editors

Darren B. Taichman et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)

Add to Collection

Review Medicine, General & Internal

Progress in evidence-based medicine: a quarter century on

Benjamin Djulbegovic et al.

LANCET (2017)

Add to Collection

Article Anesthesiology

An Appraisal of the Carlisle-Stouffer-Fisher Method for Assessing Study Data Integrity and Fraud

Edward J. Mascha et al.

ANESTHESIA AND ANALGESIA (2017)

Add to Collection

Article Anesthesiology

Data fabrication and other reasons for non-random sampling in 5087 randomised, controlled trials in anaesthetic and general medical journals

J. B. Carlisle

ANAESTHESIA (2017)

Add to Collection

Editorial Material Obstetrics & Gynecology

The CROWN Initiative journal editors invite researchers to develop core outcomes in women's health

Khalid Khan

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2016)

Add to Collection

Editorial Material Multidisciplinary Sciences

Don't let transparency damage science

Stephan Lewandowsky et al.

NATURE (2016)

Add to Collection

Review Clinical Neurology

Systematic review and statistical analysis of the integrity of 33 randomized controlled trials

Mark J. Bolland et al.

NEUROLOGY (2016)

Add to Collection

Editorial Material Medicine, General & Internal

Assessing the Gold Standard - Lessons from the History of RCTs

Laura E. Bothwell et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Add to Collection

Review Orthopedics

The COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) and how to select an outcome measurement instrument

Lidwine B. Mokkink et al.

BRAZILIAN JOURNAL OF PHYSICAL THERAPY (2016)

Add to Collection

Article Anesthesiology

Calculating the probability of random sampling for continuous variables in submitted or published randomised controlled trials

J. B. Carlisle et al.

ANAESTHESIA (2015)

Add to Collection

Article Medicine, General & Internal

Correcting the scientific literature: retraction and republication

The Lancet

LANCET (2015)

Add to Collection

Article Multidisciplinary Sciences

The Precision-Recall Plot Is More Informative than the ROC Plot When Evaluating Binary Classifiers on Imbalanced Datasets

Takaya Saito et al.

PLOS ONE (2015)

Add to Collection

Article Anesthesiology

The analysis of 168 randomised controlled trials to test data integrity

J. B. Carlisle

ANAESTHESIA (2012)

Add to Collection

Article Surgery

The Levels of Evidence and Their Role in Evidence-Based Medicine

Patricia B. Burns et al.

PLASTIC AND RECONSTRUCTIVE SURGERY (2011)

Add to Collection

News Item Multidisciplinary Sciences

Psychologist Accused of Fraud on 'Astonishing Scale'

Gretchen Vogel

SCIENCE (2011)

Add to Collection

Article Health Care Sciences & Services

The COSMIN checklist for evaluating the methodological quality of studies on measurement properties: A clarification of its content

Lidwine B. Mokkink et al.

BMC MEDICAL RESEARCH METHODOLOGY (2010)

Add to Collection

Article Medicine, General & Internal

Tanezumab for the Treatment of Pain from Osteoarthritis of the Knee

Nancy E. Lane et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Add to Collection

Article Medical Ethics

Research Misconduct Policies of Scientific Journals

DAVID B. RESNIK et al.

Accountability in Research-Policies and Quality Assurance (2009)

Add to Collection

Article Obstetrics & Gynecology

Vaginal repair with mesh versus colporrhaphy for prolapse: a randomised controlled trial

M. Carey et al.

BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY (2009)

Add to Collection

Review Health Care Sciences & Services

A review of solutions for diagnostic accuracy studies with an imperfect or missing reference standard

Johannes B. Reitsma et al.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2009)

Add to Collection

Article Multidisciplinary Sciences

How Many Scientists Fabricate and Falsify Research? A Systematic Review and Meta-Analysis of Survey Data

Daniele Fanelli

PLOS ONE (2009)

Add to Collection

Article Medicine, General & Internal

Why most published research findings are false

JPA Ioannidis

PLOS MEDICINE (2005)

Add to Collection

Article Obstetrics & Gynecology

A randomized, controlled trial of open versus closed vaginal vault at vaginal hysterectomy

JK Gupta et al.

ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA (2005)

Add to Collection

Article Health Care Sciences & Services

Reporting of measures of accuracy in systematic reviews of diagnostic literature

H Honest et al.

BMC HEALTH SERVICES RESEARCH (2002)

Add to Collection

Article Medicine, General & Internal

The CONSORT statement: Revised recommendations for improving the quality of reports of parallel-group randomized trials

D Moher et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2001)

Add to Collection

© Peeref 2019-2024. All rights reserved.