Plant-based bioactive peptides: a review of their relevant production strategies, in vivo bioactivities, action mechanisms and bioaccessibility

The current global trend towards green and environmentally sustainable food sources has favoured plant-based foods over animal-based food products. Plants supply most of the required energy for the sustenance of all life forms on earth, and their health-promoting qualities are mostly derived from their extracts and protein components, which make plant-based bioactive peptides (BPs) great human health contributors. So many biological activities of these BPs have been reported in vitro but their demonstrated effects may not be the same as those found in in vivo studies. Therefore, this review is aimed at exploring recent literature on the demonstrated in vivo bioactivities of plant-based BPs. The production of the peptides together with in vivo shreds of evidence are presented and their biological activities like antihypertensive, neuroprotective, and antioxidant effects are exemplified. Furthermore, some of the BP's mechanism of action along with their bioaccessibility inferences are described. Further considerations and concluding remarks on the therapeutic and commercialization potentials of plant-based BPs are discussed.

Automated summary

The increasing global demand for green and sustainable food sources has led to a preference for plant-based foods over animal-based products. Plant-based bioactive peptides (BPs) have been shown to have numerous health-promoting qualities. This review explores the demonstrated in vivo bioactivities of plant-based BPs, including their production, biological effects, and mechanisms of action. The potential therapeutic and commercialization prospects of these BPs are also discussed.