4.7 Article

Improving the protective ability of lignin against vascular and neurological development in BPAF-induced zebrafish by high-pressure homogenization technology

Related references

Note: Only part of the references are listed.
Article Green & Sustainable Science & Technology

Lignin-enzyme interaction: A roadblock for efficient enzymatic hydrolysis of lignocellulosics

Caoxing Huang et al.

Summary: Efficiently producing second-generation biofuels from biomass remains a long-term challenge due to biomass recalcitrance. Lignin significantly contributes to biomass recalcitrance by physically limiting enzyme access to carbohydrates. Research is focused on mitigating the negative effects of lignin on enzyme performance.

RENEWABLE & SUSTAINABLE ENERGY REVIEWS (2022)

Article Environmental Sciences

A systematic comparison of neurotoxicity of bisphenol A and its derivatives in zebrafish

Jie Gu et al.

Summary: The study compared the neurotoxicity of four BPs on zebrafish and found that BPAF, BPF, and BPA exposure significantly reduced locomotor activity in the larvae. Additionally, BPAF adversely affected motor neuron axon length and CNS neurogenesis. BPAF displayed the strongest effects on neurotransmitters levels, followed by BPF and BPA, while BPS showed the weakest effects.

SCIENCE OF THE TOTAL ENVIRONMENT (2022)

Article Engineering, Biomedical

How far is Lignin from being a biomedical material?

Sigit Sugiarto et al.

Summary: The review highlights the potential of utilizing lignin as a versatile biomaterial and discusses the challenges and outlook in developing and enhancing biomaterials through chemical modifications of lignin.

BIOACTIVE MATERIALS (2022)

Article Cardiac & Cardiovascular Systems

Effects of FW2 Nanoparticles Toxicity in a New In Vitro Pulmonary Vascular Cells Model Mimicking Endothelial Dysfunction

J. Deweirdt et al.

Summary: Several epidemiological studies have indicated the involvement of nanoparticles (NPs) in respiratory and cardiovascular mortality. This study focused on carbon black NPs and their toxic effects in the pulmonary circulation, particularly under pathological conditions, where oxidative stress, inflammation, and calcium signaling alterations were found to be increased.

CARDIOVASCULAR TOXICOLOGY (2022)

Article Environmental Sciences

A systematic comparison of the developmental vascular toxicity of bisphenol A and its alternatives in vivo and in vitro

Guixiang Ji et al.

Summary: This study evaluated the developmental vascular toxicity of bisphenol A (BPA) and its substitutes using zebrafish embryos and human vascular endothelial cells (HUVECs). The results showed that the substitutes hindered vascular growth and inhibited in vitro angiogenesis. BP exposure also increased oxidative stress. The ranking of toxicity and oxidative stress potency of the substitutes was BPAF > BPF > BPA > BPS.

CHEMOSPHERE (2022)

Review Biochemistry & Molecular Biology

A review on lignin antioxidants: Their sources, isolations, antioxidant activities and various applications

Xinyu Lu et al.

Summary: This review summarizes the research progress on lignin antioxidants extracted from biomass resources, methods to improve their antioxidant activity, and their applications. Phenolic content is considered as the most important factor affecting lignin antioxidant activity, and studies have focused on pretreatments and post-processing methods to enhance their activity. Lignin is regarded as a potential natural antioxidant alternative and has the potential for application as an inexpensive antioxidant additive.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

Article Environmental Sciences

Environmental level of bisphenol F induced reproductive toxicity toward zebrafish

Xiyan Mu et al.

Summary: Bisphenol F (BPF) had negative effects on the reproductive capacity and development of zebrafish, especially showing pathological changes in female gonads and affecting the fertility rate of male fish. Exposure to BPF led to abnormal development in F1 generation embryos and altered genes involved in skeletal/cardiac muscle development. The enriched pathways in the offspring varied depending on the BPF concentration, with regulators like GATA4, MYF6, and MEF2C mediating the observed changes.

SCIENCE OF THE TOTAL ENVIRONMENT (2022)

Review Biochemistry & Molecular Biology

Sustainable lignin and lignin-derived compounds as potential therapeutic agents for degenerative orthopaedic diseases: A systemic review

Wenhui Pei et al.

Summary: Lignin and its derivatives have potential therapeutic effects in treating degenerative orthopaedic diseases, as their excellent biological activities can regulate inflammation and bone remodeling, providing new strategies for clinical treatments.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

Review Engineering, Biomedical

Advances in the development of tubular structures using extrusion-based 3D cell-printing technology for vascular tissue regenerative applications

Gi Hoon Yang et al.

Summary: Currently, there is a lack of ideal small diameter vascular grafts on the market, making vascular tissue engineering a promising solution. This review article introduces the extrusion-based 3D cell-printing technique, which is capable of mimicking the natural structure of blood vessels.

BIOMATERIALS RESEARCH (2022)

Review Chemistry, Multidisciplinary

Lignin for energy applications - state of the art, life cycle, technoeconomic analysis and future trends

Anne Beaucamp et al.

Summary: Lignin, a by-product of papermaking and biofuel industries, is a valuable sustainable polymer suitable for high value energy applications. This review discusses lignin chemistry, extraction techniques, and important chemistries for emerging energy applications.

GREEN CHEMISTRY (2022)

Article Engineering, Environmental

The comparative toxicities of BPA, BPB, BPS, BPF, and BPAF on the reproductive neuroendocrine system of zebrafish embryos and its mechanisms

Wenhui Qiu et al.

Summary: The study found that BPA and its analogs stimulate the reproductive neuroendocrine system in zebrafish, increasing the expression levels of related genes and typical hormones. These effects were associated with increased activity of estrogen receptors and aromatase. Additionally, BPAF exhibited similar reproductive neuroendocrine toxicity to BPA in aquatic organisms.

JOURNAL OF HAZARDOUS MATERIALS (2021)

Article Engineering, Environmental

Rapid Zebrafish Behavioral Profiling Assay Accelerates the Identification of Environmental Neurodevelopmental Toxicants

Kun Zhang et al.

Summary: A rapid zebrafish behavioral profiling assay was developed to quantify the neurodevelopmental effects of environmental substances and provide additional information. The assay successfully captured the impacts of different neuroactive substances on spontaneous movement. Additionally, the web-based tool EMAnalysis was provided to accelerate the discovery of neurotoxic environmental contaminants.

ENVIRONMENTAL SCIENCE & TECHNOLOGY (2021)

Review Biotechnology & Applied Microbiology

Lignin nanoparticles enter the scene: A promising versatile green tool for multiple applications

Willian Daniel Hahn Schneider et al.

Summary: Lignin nanoparticles are considered a green and sustainable way to utilize renewable resources in various applications. Produced from different lignin types using different methods, these nanoparticles exhibit varying characteristics in terms of morphology, size, and stability. Studies have shown their potential in fields such as antioxidants, drug carriers, and more, making them a promising area of research in biotechnology and green chemistry.

BIOTECHNOLOGY ADVANCES (2021)

Article Biochemistry & Molecular Biology

Protective Effects of Lignin-Carbohydrate Complexes from Wheat Stalk against Bisphenol a Neurotoxicity in Zebrafish via Oxidative Stress

Jie Gu et al.

Summary: The study demonstrated the neuroprotective effects of lignin-carbohydrate complexes (LCCs) extracted from wheat stalk against BPA neurotoxicity in zebrafish. LCCs were able to reduce oxidative stress and suppress the mRNA expression level of key genes related to nerves, demonstrating potential as neuroprotective agents. Carbohydrate-rich LCCs showed stronger antioxidant activity compared to lignin-rich LCCs under BPA exposure.

ANTIOXIDANTS (2021)

Article Biochemistry & Molecular Biology

Safety aspects of kraft lignin fractions: Discussions on the in chemico antioxidant activity and the induction of oxidative stress on a cell-based in vitro model

Emanoela Lundgren Tha et al.

Summary: Lignin, a complex phenolic biopolymer found in plant cell walls, has potential health benefits as a natural active ingredient due to its antioxidant properties. However, further investigation is needed on the safety aspects of lignin fractions. Research showed that while certain lignin fractions demonstrated antioxidant activity in the DPPH assay, they also led to intracellular ROS generation and oxidative DNA damage in HepG2 cells. Additional toxicological evaluations are necessary to assess the risks associated with kraft lignins obtained by acid precipitation.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2021)

Review Nanoscience & Nanotechnology

Vascularization Approaches in Tissue Engineering: Recent Developments on Evaluation Tests and Modulation

Soraia Lopes et al.

Summary: This review focuses on vascularization in tissue engineering, discussing the formation of vascular networks within scaffolds and their ability to connect to the patient's vasculature. It also explores the development of angiogenesis techniques and monitoring methods, and how these can be utilized to tailor vascularization in large tissue engineered constructs. Finally, it offers an outlook on vascularization and emerging bioprinting concepts in tissue engineering applications.

ACS APPLIED BIO MATERIALS (2021)

Article Environmental Sciences

Bisphenol F exposure impairs neurodevelopment in zebrafish larvae (Danio rerio)

Jie Gu et al.

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2020)

Review Toxicology

Antioxidants and antioxidant methods: an updated overview

Ilhami Gulcin

ARCHIVES OF TOXICOLOGY (2020)

Article Chemistry, Multidisciplinary

Structural and Morphological Transformations of Lignin Macromolecules during Bio-Based Deep Eutectic Solvent (DES) Pretreatment

Xiao-Jun Shen et al.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2020)

Review Green & Sustainable Science & Technology

Lignin as a potential source of high-added value compounds: A review

Luis Alberto Zevallos Torres et al.

JOURNAL OF CLEANER PRODUCTION (2020)

Review Biochemistry & Molecular Biology

Valorization of lignin in polymer and composite systems for advanced engineering applications - A review

Maurice N. Collins et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Article Agricultural Engineering

A concise review of current lignin production, applications, products and their environmental impact

D. S. Bajwa et al.

INDUSTRIAL CROPS AND PRODUCTS (2019)

Review Medicine, General & Internal

Antioxidant Therapies for Neuroprotection-A Review

Raluca Ioana Teleanu et al.

JOURNAL OF CLINICAL MEDICINE (2019)

Article Chemistry, Multidisciplinary

Green and Facile Preparation of Regular Lignin Nanoparticles with High Yield and Their Natural Broad-Spectrum Sunscreens

Bing Wang et al.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2019)

Review Nutrition & Dietetics

Potentialities and Limits of Some Non-thermal Technologies to Improve Sustainability of Food Processing

Laetitia Picart-Palmade et al.

FRONTIERS IN NUTRITION (2019)

Review Biochemistry & Molecular Biology

Antioxidant therapy for management of oxidative stress induced hypertension

Khalil Ali Ahmad et al.

FREE RADICAL RESEARCH (2017)

Article Chemistry, Multidisciplinary

Lignin Nanoparticle as a Novel Green Carrier for the Efficient Delivery of Resveratrol

Lin Dai et al.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2017)

Article Biotechnology & Applied Microbiology

Lignin valorization: lignin nanoparticles as high-value bio-additive for multifunctional nanocomposites

Dong Tian et al.

BIOTECHNOLOGY FOR BIOFUELS (2017)

Article Chemistry, Multidisciplinary

Synthesis and Characterization of Biodegradable Lignin Nanoparticles with Tunable Surface Properties

Alexander P. Richter et al.

LANGMUIR (2016)

Review Cell Biology

Neuroprotection and antioxidants

Maria Lalkovicova et al.

NEURAL REGENERATION RESEARCH (2016)

Review Biotechnology & Applied Microbiology

Zebrafish as tools for drug discovery

Calum A. MacRae et al.

NATURE REVIEWS DRUG DISCOVERY (2015)

Article Materials Science, Multidisciplinary

Synthesis, Characterization and Application of Lignin Nanoparticles (LNPs)

Arun Kumar Gupta et al.

MATERIALS FOCUS (2014)

Review Cardiac & Cardiovascular Systems

Antioxidants, inflammation and cardiovascular disease

Harald Mangge et al.

WORLD JOURNAL OF CARDIOLOGY (2014)

Review Neurosciences

Making myelin basic protein - from mRNA transport to localized translation

Christina Mueller et al.

FRONTIERS IN CELLULAR NEUROSCIENCE (2013)

Review Biotechnology & Applied Microbiology

Toxic Effects of Mercury on the Cardiovascular and Central Nervous Systems

Bruna Fernandes Azevedo et al.

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2012)

Article Multidisciplinary Sciences

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

Ursula Fuenfschilling et al.

NATURE (2012)

Article Developmental Biology

Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries

Benjamin M. Hogan et al.

DEVELOPMENT (2009)

Article Multidisciplinary Sciences

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

Tuomas Tammela et al.

NATURE (2008)

Article Pharmacology & Pharmacy

Zebrafish: An emerging model system for human disease and drug discovery

G. Kari et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2007)

Article Multidisciplinary Sciences

Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries

Arndt F. Siekmann et al.

NATURE (2007)

Article Chemistry, Applied

Antioxidant activity of some leafy vegetables of India: A comparative study

Nabasree Dasgupta et al.

FOOD CHEMISTRY (2007)

Article Neurosciences

Characterization of myelination in the developing zebrafish

C Brösamle et al.