☆ 4.3 Editorial Material

Is Expectant Management Noninferior to Early Ibuprofen for Patent Ductus Arteriosus?

INDIAN PEDIATRICS (2023)

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Article Medicine, General & Internal

Expectant Management or Early Ibuprofen for Patent Ductus Arteriosus

Tim Hundscheid et al.

Summary: This trial showed that in the treatment of PDA in extremely preterm infants, expectant management was noninferior to early ibuprofen treatment in terms of necrotizing enterocolitis, bronchopulmonary dysplasia, or death at 36 weeks' postmenstrual age.

NEW ENGLAND JOURNAL OF MEDICINE (2023)

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Review Pediatrics

Factors Associated With Benefit of Treatment of Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-Analysis

Esther J. S. Jansen et al.

Summary: Pharmacological treatment of PDA may reduce the incidence of severe IVH in extremely preterm, extremely low birth weight infants, or if treatment with indomethacin was started within 24 hours of birth. No other beneficial effects of pharmacological treatment were found.

FRONTIERS IN PEDIATRICS (2021)

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Article Multidisciplinary Sciences