4.8 Article

A Multimaterial Bioink Method for 3D Printing Tunable, Cell-Compatible Hydrogels

Journal

ADVANCED MATERIALS
Volume 27, Issue 9, Pages 1607-1614

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.201405076

Keywords

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Funding

  1. NCI CCSG [P30 CA060553]
  2. NSF [DMR-0520513]
  3. Engineering Center [EEC-0118025|003]
  4. Peptide and Equipment Core Facilities at the Simpson Querrey Institute for BioNanotechnology at Northwestern University from U.S. Army Research Office
  5. U.S. Army Medical Research and Materiel Command
  6. Northwestern University
  7. National Institutes of Health [1K01DK099454-01]
  8. National Science Foundation

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A multimaterial bio-ink method using polyethylene glycol crosslinking is presented for expanding the biomaterial palette required for 3D bioprinting of more mimetic and customizable tissue and organ constructs. Lightly crosslinked, soft hydrogels are produced from precursor solutions of various materials and 3D printed. Rheological and biological characterizations are presented, and the promise of this new bio-ink synthesis strategy is discussed.

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