Journal
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY
Volume 13, Issue 6, Pages 1011-1017Publisher
SPRINGER
DOI: 10.1007/s13738-016-0814-1
Keywords
Ionic liquid; Succinic anhydride; Multi-component reaction; Neat conditions
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Funding
- Shahid Bahonar University of Kerman Faculty Research Committee
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A series of 3,4,7,8-tetrahydro-3,3-dimethyl-11-aryl-2H-pyridazino[1,2-a]indazole-1,6,9(11H)-trione derivatives have been synthesized via one-pot, four-component reaction in the presence of 3-methyl-1-butyl imidazolium hydroxide as an efficient catalyst. A broad range of structurally diverse aldehydes (aromatic aldehydes bearing electron withdrawing and electron releasing groups) was applied successfully, and corresponding products were obtained in good to excellent yields without any by-product. The catalyst was stable during the reaction process and could also be reused several times with consistent activity.
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