Related references
Note: Only part of the references are listed.
Article
Medicine, General & Internal
Christopher C. Butler et al.
Summary: This study aimed to determine the safety, effectiveness, and cost-effectiveness of molnupiravir in vaccinated high-risk patients in the community. The results showed that molnupiravir did not reduce hospital admissions or deaths associated with COVID-19 compared to usual care in this population.
Article
Biochemistry & Molecular Biology
Qian Wang et al.
Summary: The BQ and XBB subvariants of SARS-CoV-2 Omicron, with additional spike mutations, are rapidly expanding and have altered antibody evasion properties. Neutralization of BQ.1, BQ.1.1, XBB, and XBB.1 by vaccinated individuals and infected persons' sera was significantly impaired, including those boosted with a WA1/BA.5 bivalent mRNA vaccine. The titers against BQ and XBB subvariants were much lower than observed before, indicating that these subvariants pose a serious threat to current COVID-19 vaccines and render all authorized antibodies inactive.
Article
Medicine, General & Internal
Sinead Delany-Moretlwe et al.
Summary: The study aimed to assess the safety and efficacy of injectable cabotegravir compared with daily oral tenofovir diphosphate plus emtricitabine for HIV prevention in HIV-uninfected women. The results showed that cabotegravir was superior to TDF-FTC in preventing HIV infection among women.
Article
Medicine, General & Internal
Myron J. Levin et al.
Summary: A single dose of AZD7442 showed efficacy in preventing Covid-19 without evident safety concerns. The study suggests that AZD7442 may provide potential protection for individuals who have an inadequate response to vaccination or an increased risk of exposure.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Editorial Material
Immunology
Michael J. J. Peluso et al.
Summary: Intense investigation is being carried out to understand the predictors and determinants of post-acute sequelae of SARS-CoV-2 infection (PASC), including 'long COVID'. Recent studies provide clues to the mechanisms behind this condition, aiming to identify host or virus factors that can be intervened upon to prevent or reverse PASC.
TRENDS IN IMMUNOLOGY
(2022)
Article
Geriatrics & Gerontology
Win Min Han et al.
Summary: In this study, predictors of novel aging markers PhenoAge and PAA in people living with HIV were evaluated, with male sex, smoking, diabetes, hypertension, frailty, and high IL-6 levels independently associated with higher PAA. The PhenoAge marker showed better discrimination for frailty compared to chronological age alone, indicating its potential usefulness in identifying high-risk PLWH within a similar chronological age group.
Article
Biochemistry & Molecular Biology
Anuradhaa Subramanian et al.
Summary: A retrospective analysis of primary care records in the United Kingdom reveals individual symptoms associated with SARS-CoV-2 infections, which persisted for 12 weeks or more after infection, as well as risk factors associated with developing long COVID.
Article
Medicine, General & Internal
J. M. Palefsky et al.
Summary: Treatment for anal HSIL can significantly reduce the risk of anal cancer in persons living with HIV.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Review
Medicine, General & Internal
Kefyalew Addis Alene et al.
Summary: The management of multidrug-resistant tuberculosis (MDR-TB) during pregnancy is challenging. This study systematically synthesized treatment outcomes and adverse events among pregnant patients with MDR-TB. The results showed high treatment success rates and favorable pregnancy outcomes, providing important insights for the management of MDR-TB in pregnant patients.
Review
Medicine, General & Internal
Kin Israel Notarte et al.
Summary: This systematic review investigates the association between COVID-19 vaccination and long-COVID symptoms. The findings suggest that vaccination is associated with reduced risks of long-COVID, with preliminary evidence showing that two doses are more effective than one dose. The impact of vaccination on people with existing long-COVID symptoms is still controversial.
Article
Public, Environmental & Occupational Health
Peter A. Newman et al.
Summary: Young people aged 15-24 years in Southeast Asia account for a quarter of HIV infections, with mental health issues also being prevalent. Research has shown intersections between HIV and mental health, leading to proposed strategies for adolescent and young key populations in Indonesia, the Philippines, Thailand, and Vietnam, including youth-friendly services, parent-adolescent communication, teacher training, and youth-led education programs.
GLOBAL PUBLIC HEALTH
(2022)
Article
Medicine, General & Internal
A. Turkova et al.
Summary: In this trial involving children and adolescents with HIV-1 infection who were starting first- or second-line treatment, dolutegravir-based ART was found to be superior to standard care.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Medicine, General & Internal
Raphael J. Landovitz et al.
Summary: The study showed that injectable Cabotegravir was more effective in preventing HIV infection among MSM and transgender women compared to daily oral Tenofovir Disoproxil Fumarate-Emtricitabine. Strategies are needed to prevent INSTI resistance in cases of Cabotegravir PrEP failure.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Multidisciplinary Sciences
Mohamed Fareh et al.
Summary: The study demonstrates the reprogramming of Cas13b to target and suppress SARS-CoV-2 mutations with high efficiency. The reprogrammed Cas13b shows resilience to various SARS-CoV-2 variants, making it a potential tool for antiviral drug development.
NATURE COMMUNICATIONS
(2021)
Review
Cardiac & Cardiovascular Systems
Anoop S. V. Shah et al.
