4.7 Article

Molecular interactions between soybean glycinin (11S) and genistein using spectroscopic and in silico analyses

Related references

Note: Only part of the references are listed.
Article Chemistry, Applied

Binding parameters and molecular dynamics of β-lactoglobulin-vanillic acid complexation as a function of pH- part B: Neutral pH

Kourosh Abdollahi et al.

Summary: The study investigated the interactions between the dimeric form of beta-lactoglobulin and vanillic acid using various spectroscopic techniques and molecular dynamics (MD) simulations. Results showed changes in the protein's secondary structure upon interaction with the ligand, with a 1:1 stoichiometry for the complex at neutral pH. Molecular docking and MD simulations indicated the top-ranked binding sites of the ligand and the contribution of water molecules to the complexes.

FOOD CHEMISTRY (2022)

Article Food Science & Technology

Interaction of mulberry anthocyanins with soybean protein isolate: effect on the stability of anthocyanins and protein in vitro digestion characteristics

Zhen Ma et al.

Summary: This study investigated the interaction mechanism between soybean protein isolate (SPI) and mulberry anthocyanins (MA) and found that it affects the thermal stability of anthocyanins and the digestibility of protein subunits.

INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY (2022)

Article Chemistry, Applied

Effect of low frequency ultrasound on the functional characteristics of isolated lupin protein

Billy Lo et al.

Summary: Sonication was effective in improving the particle size, solubility, and gelling properties of lupin protein isolates, with a more significant impact on the pH 5 sample compared to the pH 9 sample. Ultrasound treatment also reduced particle size to below 10 μm for pH 5 and below 1 μm for pH 9, while increasing solubility across the pH profile. However, the gelling properties of the pH 9 sample were not significantly improved despite sonication.

FOOD HYDROCOLLOIDS (2022)

Article Chemistry, Applied

Formation of protein-anthocyanin complex induced by grape skin extracts interacting with wheat gliadins: Multi-spectroscopy and molecular docking analysis

Ziqi Guo et al.

Summary: The interaction between grape skin anthocyanin extract and gliadin was investigated, and it was found that anthocyanins could effectively form complexes with gliadin and change its conformational properties.

FOOD CHEMISTRY (2022)

Article Food Science & Technology

Comparative study of binding interactions between different dietary flavonoids and soybean β-conglycinin and glycinin: Impact on structure and function of the proteins

Yijia Jia et al.

Summary: The mechanisms of interaction between different dietary flavonoids and soybean proteins were investigated, revealing that certain flavonoids can alter the conformation and functional properties of soybean proteins, leading to improved solubility, emulsifying properties, thermal stability, and antioxidant capacity.

FOOD RESEARCH INTERNATIONAL (2022)

Article Biochemistry & Molecular Biology

Influence of mild oxidation induced through DBD-plasma treatment on the structure and gelling properties of glycinin

Zhi-Wei Liu et al.

Summary: Dielectric-barrier discharge (DBD) plasma treatment induced mild oxidation improves the gelling properties and structural changes of glycinin. Treated glycinin forms gels with a continuous and uniform microstructure, exhibiting increased hardness, chewiness, and resilience. The primary and secondary structures of glycinin remain unchanged, while the tertiary structure shifts.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2022)

Article Chemistry, Applied

Asymmetrical flow field-flow fractionation combined with electrophoresis: A new approach for studying thermal aggregation behavior of soy protein isolate

Wei Wang et al.

Summary: This study evaluated the thermal aggregation behavior of soy protein isolate using AF4 combined with SDS-PAGE, and found that factors such as heating temperature, protein concentration, ionic strength, and type of salt can affect the aggregation behavior. Larger SPI aggregates can dissociate, rearrange, and aggregate to form smaller ones with longer heating time. Higher ionic strength promotes the formation of larger SPI aggregates. AF4 combined with SDS-PAGE is a powerful tool for studying the thermal aggregation behavior of SPIs.

FOOD HYDROCOLLOIDS (2021)

Review Food Science & Technology

Soy Protein: Molecular Structure Revisited and Recent Advances in Processing Technologies

Xiaonan Sui et al.

Summary: Rising health concerns and increasing obesity levels have led to a shift in consumer preferences towards plant-based proteins, with soy protein emerging as a versatile and well-balanced alternative to animal protein. Advances in processing technologies have enabled the production of a wide variety of functional foods and ingredients from soy proteins, offering consumers a diverse array of options in the modern food industry. The review also explores the structural changes induced by soy protein processing and revisits the molecular structure of soy protein, particularly the crystal structures of beta-conglycinin and glycinin.

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 12, 2021 (2021)

Article Chemistry, Applied

Binding parameters and molecular dynamics of β-lactoglobulin-vanillic acid complexation as a function of pH - Part A: Acidic pH

Kourosh Abdollahi et al.

Summary: This study investigates the molecular interactions between vanillic acid and beta-lactoglobulin using appropriate protocols, determining the dissociation constant and stoichiometry, and revealing significant alterations to the conformational characteristics of the protein upon complexation. Molecular dynamics simulations support a 1:1 interaction stoichiometry and highlight the dynamic nature of vanillic acid stabilization, primarily through pi-alkyl interactions and hydrogen bonding. Water molecules play a crucial role in ligand stabilization through bridging interactions, which are often overlooked in MD simulation analysis.

FOOD CHEMISTRY (2021)

Article Chemistry, Applied

High-temperature binding parameters and molecular dynamics of 4-hydroxybenzoic acid and β-casein complexes, determined via the method of continuous variation and fluorescence spectroscopy

Lloyd Condict et al.

Summary: This study investigated the interactions between beta-casein and 4-hydroxybenzoic acid (4HBA) after UHT treatment, showing strong binding and confirming the binding mechanism through different analyses. The research accurately determined binding parameters and shed light on the fate of bioactive ingredients in UHT treated beverage systems, providing important reference for the industry in product design.

FOOD HYDROCOLLOIDS (2021)

Review Biochemistry & Molecular Biology

Physiologically Active Molecules and Functional Properties of Soybeans in Human Health-A Current Perspective

Il-Sup Kim et al.

Summary: Soybeans not only provide nutrients, but also contain various phytochemical substances that promote health and have positive effects in preventing chronic diseases and treating conditions like cancer.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Chemistry, Applied

Interaction mechanisms and structure-affinity relationships between hyperoside and soybean β-conglycinin and glycinin

Di Wu et al.

Summary: This study investigated the interaction mechanisms between Hyperoside and two main soy proteins, showing that Hyperoside is stably located in the hydrophobic pockets of beta-conglycinin and glycinin. The conformation and microenvironment of the proteins changed after binding to Hyperoside, with a good affinity observed at 4 degrees C. The results suggest the potential for constructing an embedding and delivery system to enhance the benefits of Hyperoside in high value-added food products.

FOOD CHEMISTRY (2021)

Article Spectroscopy

Investigation on the interaction of heated soy proteins with anthocyanins from cornelian cherry fruits

Loredana Dumitrascu et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2020)

Review Food Science & Technology

Dairy protein-ligand interactions upon thermal processing and targeted delivery for the design of functional foods

Lloyd Condict et al.

CURRENT OPINION IN FOOD SCIENCE (2019)

Article Biochemistry & Molecular Biology

Binding interaction between β-conglycinin/glycinin and cyanidin-3-O-glucoside in acidic media assessed by multi-spectroscopic and thermodynamic techniques

Cong Ren et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)

Review Chemistry, Analytical

Inner filter effect-based fluorescent sensing systems: A review

Shuai Chen et al.

ANALYTICA CHIMICA ACTA (2018)

Review Nutrition & Dietetics

Soybean Bioactive Peptides and Their Functional Properties

Cynthia Chatterjee et al.

NUTRIENTS (2018)

Article Food Science & Technology

Analysis of binding interaction of genistein and kaempferol with bovine α-lactalbumin

Fakhrossadat Mohammadi et al.

JOURNAL OF FUNCTIONAL FOODS (2015)

Article Chemistry, Physical

UV Transition Moments of Tyrosine

Louise H. Fornander et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2014)

Review Chemistry, Applied

Current Knowledge in Soybean Composition

Jelena Medic et al.

JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY (2014)

Article Chemistry, Physical

Binding Sites of Resveratrol, Genistein, and Curcumin with Milk α- and β-Caseins

P. Bourassa et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2013)

Article Chemistry, Physical

Binding Interactions of β-Conglycinin and Glycinin with Vitamin B12

Jing Zhang et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2013)

Article Chemistry, Physical

Fluorescence quenching and ligand binding: A critical discussion of a popular methodology

Marco van de Weert et al.

JOURNAL OF MOLECULAR STRUCTURE (2011)

Article Agriculture, Multidisciplinary

Heat-induced gelation of pea legumin: Comparison with soybean glycinin

FE O'Kane et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2004)

Article Agriculture, Multidisciplinary

Structural characteristics of purified glycinin from soybeans stored under various conditions

DH Hou et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Interactions of different phenolic acids and flavonoids with soy proteins

HM Rawel et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2002)

Article Agriculture, Multidisciplinary

Heat denaturation of soy glycinin: Influence of pH and ionic strength on molecular structure

CMM Lakemond et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2000)