4.7 Review

RIFM fragrance ingredient safety assessment,2-methyl-2-propanol, CAS registry number 75-65-0

Related references

Note: Only part of the references are listed.
Article Dermatology

Fragrance Skin Sensitization Evaluation and Human Testing: 30-Year Experience

Mihwa Na et al.

Summary: The Human Repeated Insult Patch Test (HRIPT) has been widely used in the fragrance industry to confirm the absence of skin sensitization at a defined dose. After accumulated experience of over 30 years, most studies have shown that sensitization was not induced at the selected HRIPT dose, but a minority of cases exist. New sensitization induction is rare but important as an indicator that toxicological predictions from nonhuman test methods can be imperfect.

DERMATITIS (2021)

Article Medicine, Legal

Comparison of Cramer classification between Toxtree, the OECD QSAR Toolbox and expert judgment

Sneha Bhatia et al.

REGULATORY TOXICOLOGY AND PHARMACOLOGY (2015)

Article Medicine, Legal

Novel database for exposure to fragrance ingredients in cosmetics and personal care products

D. Comiskey et al.

REGULATORY TOXICOLOGY AND PHARMACOLOGY (2015)

Article Medicine, Legal

A strategy for structuring and reporting a read-across prediction of toxicity

T. W. Schultz et al.

REGULATORY TOXICOLOGY AND PHARMACOLOGY (2015)

Article Food Science & Technology

An in silico skin absorption model for fragrance materials

Jie Shen et al.

FOOD AND CHEMICAL TOXICOLOGY (2014)

Article Chemistry, Multidisciplinary

CAESAR models for developmental toxicity

Antonio Cassano et al.

CHEMISTRY CENTRAL JOURNAL (2010)

Review Toxicology

Tertiary-Butanol: A toxicological review

Douglas McGregor

CRITICAL REVIEWS IN TOXICOLOGY (2010)

Article Chemistry, Medicinal

Extended-Connectivity Fingerprints

David Rogers et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2010)

Article Biochemistry & Molecular Biology

Can light absorption and photostability data be used to assess the photosafety risks in patients for a new drug molecule?

Brian Henry et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2009)

Article Food Science & Technology

Application of the threshold of toxicological concern (TTC) to the safety evaluation of cosmetic ingredients

R. Kroes et al.

FOOD AND CHEMICAL TOXICOLOGY (2007)

Article Chemistry, Medicinal

Mechanistic applicability domain classification of a local lymph node assay dataset for skin sensitization

David W. Roberts et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2007)

Article Biotechnology & Applied Microbiology

The mutagenicity testing of tertiary-butyl alcohol, tertiary-butyl acetate™ and methyl tertiary-butyl ether in Salmonella typhimurium

DB McGregor et al.

MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2005)