Related references
Note: Only part of the references are listed.New aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the hydroxytriazole scaffold
Agnese Chiara Pippione et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022)
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety br
Stefano Sainas et al.
JOURNAL OF MEDICINAL CHEMISTRY (2022)
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Biphenyl Moiety
Stefano Sainas et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Targeting Genome Integrity in Mycobacterium Tuberculosis: From Nucleotide Synthesis to DNA Replication and Repair
Riccardo Miggiano et al.
MOLECULES (2020)
Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies
Agnese C. Pippione et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Pyrimidine biosynthesis in pathogens - Structures and analysis of dihydroorotases from Yersinia pestis and Vibrio cholerae
Joanna Lipowska et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2019)
Structural basis for the design of selective inhibitors for Schistosoma mansoni dihydroorotate dehydrogenase
M. Cristina Nonato et al.
BIOCHIMIE (2019)
Dihydroorotate dehydrogenase inhibitors in anti-infective drug research
Donatella Boschi et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors
Stefano Sainas et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds
Stefano Sainas et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Every OGT Is Illuminated ... by Fluorescent and Synchrotron Lights
Riccardo Miggiano et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
The dihydroorotate dehydrogenases: Past and present
Renata A. G. Reis et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2017)
Fine tuning of the active site modulates specificity in the interaction of O-acetylserine sulfhydrylase isozymes with serine acetyltransferase
Francesca Spyrakis et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2013)
Synthesis and Pharmacological Evaluation of 4-Iminothiazolidinones for Inhibition of PI3 Kinase
Jo-Anne Pinson et al.
AUSTRALIAN JOURNAL OF CHEMISTRY (2012)
The structure-activity relationship of urea derivatives as anti-tuberculosis agents
Joshua R. Brown et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2011)
Pyrimidine Salvage Pathway in Mycobacterium tuberculosis
A. D. Villela et al.
CURRENT MEDICINAL CHEMISTRY (2011)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
The ID23-2 structural biology microfocus beamline at the ESRF
David Flot et al.
JOURNAL OF SYNCHROTRON RADIATION (2010)
Roles in Binding and Chemistry for Conserved Active Site Residues in the Class 2 Dihydroorotate Dehydrogenase from Escherichia coli
Rebecca L. Fagan et al.
BIOCHEMISTRY (2009)
Structures of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with substrates and products:: Atomic resolution insights into mechanisms of dihydroorotate oxidation and fumarate reduction
Daniel Ken Inaoka et al.
BIOCHEMISTRY (2008)
Nucleotide biosynthesis is critical for growth of bacteria in human blood
Shalaka Samant et al.
PLOS PATHOGENS (2008)
Coot:: model-building tools for molecular graphics
P Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)
De novo pyrimidine biosynthesis is required for virulence of Toxoplasma gondii
BA Fox et al.
NATURE (2002)
Share Paper
