Related references
Note: Only part of the references are listed.EGFR Signaling in Lung Fibrosis
Fabian Schramm et al.
CELLS (2022)
How to treat gastrinomas in patients with multiple endocrine neoplasia type1: surgery or long-term proton pump inhibitors?
Masayuki Imamura et al.
SURGERY TODAY (2022)
Multi-omics analyses of MEN1 missense mutations identify disruption of menin-MLL and menin-JunD interactions as critical requirements for molecular pathogenicity
Koen M. A. Dreijerink et al.
EPIGENETICS & CHROMATIN (2022)
Epigenetic Regulation in Gastroenteropancreatic Neuroendocrine Tumors
Judy S. Crabtree
FRONTIERS IN ONCOLOGY (2022)
GFAP-directed Inactivation of Men1 Exploits Glial Cell Plasticity in Favor of Neuroendocrine Reprogramming
Suzann Duan et al.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2022)
Context matters - Daxx and Atrx are not robust tumor suppressors in the murine endocrine pancreas
Chang Sun et al.
DISEASE MODELS & MECHANISMS (2022)
Genetics of Pancreatic Neuroendocrine Tumors
Chirayu Mohindroo et al.
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA (2022)
The Next Generation of KRAS Targeting: Reasons for Excitement and Concern
Neal S. Akhave et al.
MOLECULAR CANCER THERAPEUTICS (2022)
Targeting Extracellular Signal-Regulated Protein Kinase 1/2 (ERK1/2) in Cancer: An Update on Pharmacological Small-Molecule Inhibitors
Leilei Fu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2022)
Multiple Endocrine Neoplasia Type 1 (MEN1) 5′UTRDeletion, inMEN1Family, Decreases Menin Expression
Kreepa G. Kooblall et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2021)
Multiple Endocrine Neoplasia Type 1: Latest Insights
Maria Luisa Brandi et al.
ENDOCRINE REVIEWS (2021)
Genome analysis identifies differences in the transcriptional targets of duodenal versus pancreatic neuroendocrine tumours
Karen Rico et al.
BMJ OPEN GASTROENTEROLOGY (2021)
Heterogeneity of the Clinical Presentation of the MEN1 LRG_509 c.781C>>T (p.Leu261Phe) Variant Within a Three-Generation Family
Aleksandra Gilis-Januszewska et al.
GENES (2021)
Cross-talk among MEN1, p53 and Notch regulates the proliferation of pancreatic neuroendocrine tumor cells by modulating INSM1 expression and subcellular localization
Ylenia Capodanno et al.
NEOPLASIA (2021)
Gastrin: From Physiology to Gastrointestinal Malignancies
Suzann Duan et al.
FUNCTION (2021)
Tumor microenvironment complexity and therapeutic implications at a glance
Roghayyeh Baghba et al.
CELL COMMUNICATION AND SIGNALING (2020)
The MAPK and AMPK signalings: interplay and implication in targeted cancer therapy
Jimin Yuan et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
Comprehensive Analysis of MEN1 Mutations and Their Role in Cancer
Devi D. Nelakurti et al.
CANCERS (2020)
mTOR Pathway in Gastroenteropancreatic Neuroendocrine Tumor (GEP-NETs)
Sara Zanini et al.
FRONTIERS IN ENDOCRINOLOGY (2020)
Clinical Epigenetics of Neuroendocrine Tumors: The Road Ahead
Annamaria Colao et al.
FRONTIERS IN ENDOCRINOLOGY (2020)
GLP-1 signaling suppresses menin's transcriptional block by phosphorylation in β cells
Bowen Xing et al.
JOURNAL OF CELL BIOLOGY (2019)
Multiple Endocrine Neoplasia Type 1 (MEN1): An Update and the Significance of Early Genetic and Clinical Diagnosis
Crystal D. C. Kamilaris et al.
FRONTIERS IN ENDOCRINOLOGY (2019)
Complexity of Blocking Bivalent Protein Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia Interaction
Dmitry Borkin et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Current and emerging therapies for PNETs in patients with or without MEN1
Morten Frost et al.
NATURE REVIEWS ENDOCRINOLOGY (2018)
Gastrinomas Medical or Surgical Treatment
Jeffrey A. Norton et al.
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA (2018)
Activating mutations in MEK1 enhance homodimerization and promote tumorigenesis
Jimin Yuan et al.
SCIENCE SIGNALING (2018)
Pancreatic β-Cells Express the Fetal Islet Hormone Gastrin in Rodent and Human Diabetes
Tehila Dahan et al.
DIABETES (2017)
Deletion of Men1 and somatostatin induces hypergastrinemia and gastric carcinoids
Sinju Sundaresan et al.
GUT (2017)
Epigenetic regulation by the menin pathway
Zijie Feng et al.
ENDOCRINE-RELATED CANCER (2017)
The future: genetics advances in MEN1 therapeutic approaches and management strategies
Sunita K. Agarwal
ENDOCRINE-RELATED CANCER (2017)
Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial Cells
Sinju Sundaresan et al.
GASTROENTEROLOGY (2017)
A Review of the Scaffold Protein Menin and its Role in Hepatobiliary Pathology
Laurent Ehrlich et al.
GENE EXPRESSION (2017)
Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways
Ping Wee et al.
CANCERS (2017)
Direct interaction of menin leads to ubiquitin-proteasomal degradation of β-catenin
Byungho Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Syndromic versus non-syndromic sporadic gastrin-producing neuroendocrine tumors of the duodenum: comparison of pathological features and biological behavior
M. Johannes Rosentraeger et al.
VIRCHOWS ARCHIV (2016)
Multiple endocrine neoplasia type 1 (MEN1): An update of 208 new germline variants reported in the last nine years
Paola Concolino et al.
CANCER GENETICS (2016)
Loss of Lrig1 Leads to Expansion of Brunner Glands Followed by Duodenal Adenomas with Gastric Metaplasia
Yang Wang et al.
AMERICAN JOURNAL OF PATHOLOGY (2015)
PTCH 1 staining of pancreatic neuroendocrine tumor (PNET) samples from patients with and without multiple endocrine neoplasia (MEN-1) syndrome reveals a potential therapeutic target
Buddha Gurung et al.
CANCER BIOLOGY & THERAPY (2015)
Decoding the Molecular and Mutational Ambiguities of Gastroenteropancreatic Neuroendocrine Neoplasm Pathobiology
Mark Kidd et al.
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2015)
Thoracic and duodenopancreatic neuroendocrine tumors in multiple endocrine neoplasia type 1: natural history and function of menin in tumorigenesis
C. R. C. Pieterman et al.
ENDOCRINE-RELATED CANCER (2014)
Epiregulin: Roles in normal physiology and cancer
David J. Riese et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2014)
Exploring the tumors of multiple endocrine neoplasia type 1 in mouse models for basic and preclinical studies
Sunita K. Agarwal
INTERNATIONAL JOURNAL OF ENDOCRINE ONCOLOGY (2014)
Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells
Bin E. Li et al.
BLOOD (2013)
Menin Epigenetically Represses Hedgehog Signaling in MEN1 Tumor Syndrome
Buddha Gurung et al.
CANCER RESEARCH (2013)
The embryonic transcription factor Hlxb9 is a menin interacting partner that controls pancreatic β-cell proliferation and the expression of insulin regulators
Kerong Shi et al.
ENDOCRINE-RELATED CANCER (2013)
The trithorax protein partner menin acts in tandem with EZH2 to suppress C/EBPα and differentiation in MLL-AF9 leukemia
Austin T. Thiel et al.
HAEMATOLOGICA (2013)
Hepatic menin recruits SIRT1 to control liver steatosis through histone deacetylation
Yanan Cao et al.
JOURNAL OF HEPATOLOGY (2013)
The tumor suppressor protein menin inhibits NF-κB-mediated transactivation through recruitment of Sirt1 in hepatocellular carcinoma
Ding Gang et al.
MOLECULAR BIOLOGY REPORTS (2013)
Menin Directly Represses Gli1 Expression Independent of Canonical Hedgehog Signaling
Buddha Gurung et al.
MOLECULAR CANCER RESEARCH (2013)
Menin: a scaffold protein that controls gene expression and cell signaling
Smita Matkar et al.
TRENDS IN BIOCHEMICAL SCIENCES (2013)
Conditional deletion of menin results in antral G cell hyperplasia and hypergastrinemia
Natalia A. Veniaminova et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)
Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment
Douglas Hanahan et al.
CANCER CELL (2012)
Variable clinical expression in patients with a germline MEN1 disease gene mutation: clues to a genotype-phenotype correlation
Cornelis J. Lips et al.
CLINICS (2012)
Glucose-Mediated Repression of Menin Promotes Pancreatic β-Cell Proliferation
Hongli Zhang et al.
ENDOCRINOLOGY (2012)
Interplay between Menin and K-Ras in Regulating Lung Adenocarcinoma
Yuan Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Menin Missense Mutants Encoded by the MEN1 Gene that Are Targeted to the Proteasome: Restoration of Expression and Activity by CHIP siRNA
Lucie Canaff et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
The same pocket in menin binds both MLL and JUND but has opposite effects on transcription
Jing Huang et al.
NATURE (2012)
Menin and JunD regulate gastrin gene expression through proximal DNA elements
Edith J. Mensah-Osman et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2011)
Crystal Structure of Menin Reveals Binding Site for Mixed Lineage Leukemia (MLL) Protein
Marcelo J. Murai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors
Yuchen Jiao et al.
SCIENCE (2011)
Molecular markers for novel therapies in neuroendocrine (carcinoid) tumors
Judith A. Gilbert et al.
ENDOCRINE-RELATED CANCER (2010)
c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis
Shenghao Jin et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Nuclear-Cytoplasmic Shuttling of Menin Regulates Nuclear Translocation of β-Catenin
Yanan Cao et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
SKIP Interacts with c-Myc and Menin to Promote HIV-1 Tat Transactivation
Vanessa Bres et al.
MOLECULAR CELL (2009)
Inherited pancreatic endocrine tumor syndromes: Advances in molecular pathogenesis, diagnosis, management, and controversies
Robert I. Jensen et al.
CANCER (2008)
Menin critically links MLL proteins with LEDGE on cancer-associated target genes
Akihiko Yokoyama et al.
CANCER CELL (2008)
Gastrin transactivates the chromogranin A gene through MEK-1/ERK- and PKC-dependent phosphorylation of Sp1 and CREB
Thorsten Cramer et al.
CELLULAR SIGNALLING (2008)
Menin, Histone H3 Methyltransferases, and Regulation of Cell Proliferation: Current Knowledge and Perspective
Xinjiang Wu et al.
CURRENT MOLECULAR MEDICINE (2008)
Multiple endocrine neoplaslia type 1 (MEN 1): Analysis of 1336 mutations reported in the first decade following identification of the gene
Manuel C. Lemos et al.
HUMAN MUTATION (2008)
Menin Promotes the Wnt Signaling Pathway in Pancreatic Endocrine Cells
Gao Chen et al.
MOLECULAR CANCER RESEARCH (2008)
JunD is involved in the antiproliferative effect of Δ9-tetrahydrocannabinol on human breast cancer cells
M. M. Caffarel et al.
ONCOGENE (2008)
Regulated expression of the human gastrin gene in mice
Edith Mensah-Osman et al.
REGULATORY PEPTIDES (2008)
Gastrinoma -: morphological aspects
Guenter Kloeppel et al.
WIENER KLINISCHE WOCHENSCHRIFT (2007)
Snail and Sonic Hedgehog activation in neuroendocrine tumors of the ileum
Volker Fendrich et al.
ENDOCRINE-RELATED CANCER (2007)
Endocrine precursor lesions of gastroenteropancreatic neuroendocrine tumors
Guenter Kloeppel et al.
ENDOCRINE PATHOLOGY (2007)
Broad tumor spectrum in a mouse model of multiple endocrine neoplasia type 1
Kelly A. Loffler et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Endocrine precursor lesions and microadenomas of the duodenum and pancreas with and without MEN1:: Criteria, molecular concepts and clinical significance
Martin Anlauf et al.
PATHOBIOLOGY (2007)
Menin and its interacting proteins:: elucidation of menin function
Katalin Balogh et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2006)
Multiple endocrine neoplasia type 1
Francesca Marini et al.
ORPHANET JOURNAL OF RARE DISEASES (2006)
Tumor suppressor menin: the essential role of nuclear localization signal domains in coordinating gene expression
P. La et al.
ONCOGENE (2006)
The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis
A Yokoyama et al.
CELL (2005)
Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c
SK Karnik et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Precursor lesions in patients with multiple endocrine neoplasia type 1-associated duodenal gastrinomas
M Anlauf et al.
GASTROENTEROLOGY (2005)
Signaling pathways associated with colonic mucosa hyperproliferation in mice overexpressing gastrin precursors
A Ferrand et al.
CANCER RESEARCH (2005)
Nucleocytoplasmic shuttling revealed by FRAP and FLIP technologies
M Köster et al.
CURRENT OPINION IN BIOTECHNOLOGY (2005)
Gastrin-mediated activation of cyclin D1 transcription involves β-catenin and CREB pathways in gastric cancer cells
A Pradeep et al.
ONCOGENE (2004)
Conditional inactivation of the Men1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissues
CA Biondi et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Nuclear-cytoplasmic shuttling of BARD1 contributes to its proapoptotic activity and is regulated by dimerization with BRCA1
JA Rodriguez et al.
ONCOGENE (2004)
Menin associates with a trithorax family histone methyltransferase complex and with the Hoxc8 locus
CM Hughes et al.
MOLECULAR CELL (2004)
Menin is required for bone morphogenetic protein 2- and transforming growth factor β-regulated osteoblastic differentiation through interaction with Smads and Runx2
H Sowa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Menin missense mutants associated with multiple endocrine neoplasia type 1 are rapidly degraded via the ubiquitin-proteasome pathway
H Yaguchi et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Does the use of routine duodenotomy (DUODX) affect rate of cure, development of liver metastases, or survival in patients with Zollinger-Ellison syndrome?
JA Norton et al.
ANNALS OF SURGERY (2004)
Functional characterization of a promotor region in the human MEN1 tumor suppressor gene
M Fromaget et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Heterozygous Men1 mutant mice develop a range of endocrine tumors mimicking multiple endocrine neoplasia type 1
P Bertolino et al.
MOLECULAR ENDOCRINOLOGY (2003)
The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene
KE Sukhodolets et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Menin, the multiple endocrine neoplasia type 1 gene product, exhibits GTP-hydrolyzing activity in the presence of the tumor metastasis suppressor nm23
H Yaguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Menin uncouples Elk-1, JunD and c-Jun phosphorylation from MAP kinase activation
A Gallo et al.
ONCOGENE (2002)
Menin's interaction with glial fibrillary acidic protein and vimentin suggests a role for the intermediate filament network in regulating menin activity
JR Lopez-Egido et al.
EXPERIMENTAL CELL RESEARCH (2002)
Luteinizing hormone-releasing hormone induces JunD-DNA binding and extends cell cycle in human ovarian cancer cells
AR Günthert et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Menin interacts directly with the homeobox-containing protein Pem
IH Lemmens et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
The tumor suppressor protein menin interacts with NF-κB proteins and inhibits NF-κB-mediated transactivation
C Heppner et al.
ONCOGENE (2001)
Multiple endocrine neoplasia type 1: new clinical and basic findings
DH Schussheim et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2001)
Gastric secretion in Zollinger-Ellison syndrome - Correlation with clinical expression, tumor extent and role in diagnosis - A prospective NIH study of 235 patients and a review of 984 cases in the literature
PK Roy et al.
MEDICINE (2001)
AP-1 in cell proliferation and survival
E Shaulian et al.
ONCOGENE (2001)
A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors
JS Crabtree et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The gastrins: Their production and biological activities
GJ Dockray et al.
ANNUAL REVIEW OF PHYSIOLOGY (2001)
JunD protects cells from p53-dependent senescence and apoptosis
JB Weitzman et al.
MOLECULAR CELL (2000)
Treatment of neuroendocrine GEP tumours with somatostatin analogues - A review
R Arnold et al.
DIGESTION (2000)