UNEXPECTED BEHAVIOR OF TRISILANOLISOBUTYL-POSS, KEY COMPOUND IN DRUG DELIVERY SYSTEMS, DURING MASS SPECTROMETRY ANALYSIS

The structural investigation of trisilanolisobutyl-POSS, an important precursor for biocompatible materials and drug delivery systems, was performed by (+) ESI-OT-mass spectrometry, using multiple-stage fragmentation. This allowed us to obtain a series of MS1 - MS10 spectra, which are the first to be reported in the field of organosilicon chemistry and pharmaceutical additives. The structure of the fragmentation ions was fully assigned.

Automated summary

The study investigated the structure of trisilanolisobutyl-POSS, an important precursor for biocompatible materials and drug delivery systems, using (+) ESI-OT-mass spectrometry and multiple-stage fragmentation. A series of MS1 - MS10 spectra were obtained, which are the first reported in the field of organosilicon chemistry and pharmaceutical additives. The structure of the fragmentation ions was fully assigned.