Presentation of orbital solitary fibrous tumours

AimsTo evaluate presenting features of patients with orbital solitary fibrous tumours (SFTs), based on histological phenotype.MethodsA retrospective case-note review was performed for demographics and presenting features for patients with orbital SFTs. The tumours were classified as Group IA hypocellular SFT phenotype, Group IB haemangiopericytoma phenotype and low mitotic activity, and high-grade Group II haemangiopericytoma phenotype with high mitotic activity.ResultsSixty-four patients (34 female; 53%) presented at a mean age of 42.2 years (median 38; range 19-82), with Group II patients presenting at an older age (mean 53 years). Median symptom duration was 12 months for Groups IA and IB, compared to 4 months for Group II, the commonest symptoms being proptosis (53%), diplopia (41%), periorbital swelling (31%), and altered vision (19%). Mean LogMAR was 0.17 (median 0.0; range -0.2-4), and 14% had ipsilateral optic neuropathy, with no significant difference between the three groups. Non-axial displacement was noted in 69%, a palpable mass in 45%, and reduced eye movements in 59%; choroidal folds and optic disc swelling were recorded in 12% and 9%. SFTs were mostly extraconal (59%), within the superior and superonasal quadrants (44%), with an average estimated tumour volume of 4.9 ml (median 3.6; range 0.31-14.5 ml).ConclusionSFTs may present with impaired visual function (similar to 15%), fundal abnormalities (a fifth), globe displacement (two-thirds), and reduced ocular motility (over a half). High-grade tumours tend to present more than a decade later, with a shorter duration of symptoms.

Automated summary

This study retrospectively analyzed the clinical features of 64 patients with orbital solitary fibrous tumors (SFTs), and found that common symptoms included proptosis (53%), diplopia (41%), periorbital swelling (31%), and altered vision (19%). High-grade SFTs tend to present at a later age with a shorter duration of symptoms.