Related references
Note: Only part of the references are listed.Molecular and cellular regulatory roles of sirtuin protein
Shubhra Pande et al.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2022)
ATP citrate lyase controls hematopoietic stem cell fate and supports bone marrow regeneration
Terumasa Umemoto et al.
EMBO JOURNAL (2022)
Single cell analyses identify a highly regenerative and homogenous human CD34+hematopoietic stem cell population
Fernando Anjos-Afonso et al.
NATURE COMMUNICATIONS (2022)
Loss of SIRT1 inhibits hematopoietic stem cell aging and age-dependent mixed phenotype acute leukemia
Zhiqiang Wang et al.
COMMUNICATIONS BIOLOGY (2022)
The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness
Geethu Emily Thomas et al.
NATURE CELL BIOLOGY (2022)
Metabolic Regulation of Hematopoietic Stem Cells
Claudia Morganti et al.
HEMASPHERE (2022)
Evaluation of a clinical-grade, cryopreserved, ex vivo-expanded stem cell product from cryopreserved primary umbilical cord blood demonstrates multilineage hematopoietic engraftment in mouse xenografts
Christoph Schaniel et al.
CYTOTHERAPY (2021)
CITED2 coordinates key hematopoietic regulatory pathways to maintain the HSC pool in both steady-state hematopoiesis and transplantation
Hannah Lawson et al.
STEM CELL REPORTS (2021)
A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness
Kerstin B. Kaufmann et al.
NATURE IMMUNOLOGY (2021)
The Role of Histone Protein Acetylation in Regulating Endothelial Function
Zhi Fang et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)
Integrated analysis of multimodal single-cell data
Yuhan Hao et al.
CELL (2021)
Restraining Lysosomal Activity Preserves Hematopoietic Stem Cell Quiescence and Potency
Raymond Liang et al.
CELL STEM CELL (2020)
Lipid Mediated Regulation of Adult Stem Cell Behavior
Marie Clemot et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Expansion and preservation of the functional activity of adult hematopoietic stem cells cultured ex vivo with a histone deacetylase inhibitor
Eran Zimran et al.
STEM CELLS TRANSLATIONAL MEDICINE (2020)
Ginsenoside Rg1 protects against Sca-1+ HSC/HPC cell aging by regulating the SIRT1-FOXO3 and SIRT3-SOD2 signaling pathways in a γ-ray irradiation-induced aging mice model
Yan-Long Tang et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2020)
Hematopoietic Stem Cell Metabolism during Development and Aging
Ayako Nakamura-Ishizu et al.
DEVELOPMENTAL CELL (2020)
Autophagy-Sirt3 axis decelerates hematopoietic aging
Yixuan Fang et al.
AGING CELL (2020)
Limited Mitochondrial Activity Coupled With Strong Expression of CD34, CD90 and EPCR Determines the Functional Fitness of ex vivo Expanded Human Hematopoietic Stem Cells
Luena Papa et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
Metabolism as master of hematopoietic stem cell fate
Kyoko Ito et al.
INTERNATIONAL JOURNAL OF HEMATOLOGY (2019)
The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance
Nicola Vannini et al.
CELL STEM CELL (2019)
Mitochondrial Role in Stemness and Differentiation of Hematopoietic Stem Cells
Luena Papa et al.
STEM CELLS INTERNATIONAL (2019)
SIRT1 regulates metabolism and leukemogenic potential in CML stem cells
Ajay Abraham et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
SRC-3 is involved in maintaining hematopoietic stem cell quiescence by regulation of mitochondrial metabolism in mice
Mengjia Hu et al.
BLOOD (2018)
Extra View: Sirt1 Acts As A Gatekeeper Of Replication Initiation To Preserve Genomic Stability
Koichi Utani et al.
NUCLEUS (2018)
Extra View: Sirt1 Acts As A Gatekeeper Of Replication Initiation To Preserve Genomic Stability
Koichi Utani et al.
NUCLEUS (2018)
Membrane-potential compensation reveals mitochondrial volume expansion during HSC commitment
Massimo Bonora et al.
EXPERIMENTAL HEMATOLOGY (2018)
Ex vivo human HSC expansion requires coordination of cellular reprogramming with mitochondrial remodeling and p53 activation
Luena Papa et al.
BLOOD ADVANCES (2018)
Pre-Transplantation Blockade of TNF-α-Mediated Oxygen Species Accumulation Protects Hematopoietic Stem Cells
Takashi Ishida et al.
STEM CELLS (2017)
The mitochondrial respiratory chain is essential for haematopoietic stem cell function
Elena Anso et al.
NATURE CELL BIOLOGY (2017)
A distinct hematopoietic stem cell population for rapid multilineage engraftment in nonhuman primates
Stefan Radtke et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Massively parallel digital transcriptional profiling of single cells
Grace X. Y. Zheng et al.
NATURE COMMUNICATIONS (2017)
EPCR expression marks UM171-expanded CD34+ cord blood stem cells
Iman Fares et al.
BLOOD (2017)
HSC Fate Is Tethered to Mitochondria
Lauren P. Diebold et al.
CELL STEM CELL (2016)
Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance
Kyoko Ito et al.
SCIENCE (2016)
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
Itay Tirosh et al.
SCIENCE (2016)
Specification of haematopoietic stem cell fate via modulation of mitochondrial activity
Nicola Vannini et al.
NATURE COMMUNICATIONS (2016)
Role of SIRT1 in the growth and regulation of normal hematopoietic and leukemia stem cells
Ling Li et al.
CURRENT OPINION IN HEMATOLOGY (2015)
Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3
Pauline Rimmele et al.
EMBO REPORTS (2015)
Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells
Monika S. Kowalczyk et al.
GENOME RESEARCH (2015)
A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging
Mary Mohrin et al.
SCIENCE (2015)
An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate
Maria Maryanovich et al.
NATURE COMMUNICATIONS (2015)
Epigenetic reprogramming induces the expansion of cord blood stem cells
Pratima Chaurasia et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Surviving change: the metabolic journey of hematopoietic stem cells
Latika Kohli et al.
TRENDS IN CELL BIOLOGY (2014)
Aging-like Phenotype and Defective Lineage Specification in SIRT1-Deleted Hematopoietic Stem and Progenitor Cells
Pauline Rimmele et al.
STEM CELL REPORTS (2014)
Metabolic Makeover for HSCs
Matthew R. Warr et al.
CELL STEM CELL (2013)
Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells
Keiyo Takubo et al.
CELL STEM CELL (2013)
Metabolic Regulation by the Mitochondrial Phosphatase PTPMT1 Is Required for Hematopoietic Stem Cell Differentiation
Wen-Mei Yu et al.
CELL STEM CELL (2013)
Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance
Satyendra K. Singh et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
SIRT3 Reverses Aging-Associated Degeneration
Katharine Brown et al.
CELL REPORTS (2013)
HIF-1α deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency
Jinwei Du et al.
BLOOD (2012)
SIRT1 is dispensable for function of hematopoietic stem cells in adult mice
Vid Leko et al.
BLOOD (2012)
Nicotinamide, a SIRT1 inhibitor, inhibits differentiation and facilitates expansion of hematopoietic progenitor cells with enhanced bone marrow homing and engraftment
Tony Peled et al.
EXPERIMENTAL HEMATOLOGY (2012)
Quantitative Acetylome Analysis Reveals the Roles of SIRT1 in Regulating Diverse Substrates and Cellular Pathways
Yue Chen et al.
MOLECULAR & CELLULAR PROTEOMICS (2012)
A PML-PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance
Keisuke Ito et al.
NATURE MEDICINE (2012)
SIRT1 deficiency compromises mouse embryonic stem cell hematopoietic differentiation, and embryonic and adult hematopoiesis in the mouse
Xuan Ou et al.
BLOOD (2011)
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
Toshio Suda et al.
CELL STEM CELL (2011)
AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species
Marisa M. Juntilla et al.
BLOOD (2010)
Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation
Xiaolei Qiu et al.
CELL METABOLISM (2010)
Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells
Shin-Ichi Inoue et al.
FEBS LETTERS (2010)
ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays
Yifang Hu et al.
JOURNAL OF IMMUNOLOGICAL METHODS (2009)
Mitochondrial metabolism modulates differentiation and teratoma formation capacity in mouse embryonic stem cells
Stefan M. Schieke et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
Chong Chen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
Jill C. Milne et al.
NATURE (2007)
A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche
Yoon-Young Jang et al.
BLOOD (2007)
Cited2 is required for normal hematopoiesis in the murine fetal liver
Yu Chen et al.
BLOOD (2007)
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
Zuzana Tothova et al.
CELL (2007)
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
K Ito et al.
NATURE MEDICINE (2006)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Sirtuins: Sir2-related NAD-dependent protein deacetylases
BJ North et al.
GENOME BIOLOGY (2004)
PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes
VK Mootha et al.
NATURE GENETICS (2003)
A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis
LH Kasper et al.
NATURE (2002)
The AFT024 stromal cell line supports long-term ex vivo maintenance of engrafting multipotent human hematopoietic progenitors
JA Nolta et al.
LEUKEMIA (2002)
Share Paper
