The Oxidation of Organo-Boron Compounds Using Electrochemically Generated Peroxodicarbonate

Peroxodicarbonate represents a green and largely underexplored oxidizer generated electrochemically from aqueous carbonate solutions. Through state-of-the-art electrolyzer technology, highly concentrated solutions have now become accessible. These were successfully employed as green oxidizer in deborolative hydroxylations. A plethora of phenols and alcohols have thus been synthesized in up to 99 % from organoboron compounds using only green and non-toxic solvents. This transformation was successfully scaled-up to multi-gram batch sizes.

Automated summary

Peroxodicarbonate is a green and underexplored oxidizer generated electrochemically from aqueous carbonate solutions. With advanced electrolyzer technology, highly concentrated solutions are now accessible. These solutions have been successfully used as green oxidizers in deborolative hydroxylations, leading to the synthesis of a variety of phenols and alcohols with yields up to 99% from organoboron compounds using environmentally friendly solvents. The scalability of this transformation to multi-gram batch sizes has also been demonstrated.