4.5 Article

F-Tag Induced Acyl Shift in the Photochemical Cyclization of o-Alkynylated N-Alkyl-N-acylamides to Indoles

Related references

Note: Only part of the references are listed.
Article Chemistry, Organic

Visible-light-induced and copper-catalyzed oxidative cyclization of substituted o-aminophenylacetylene for the synthesis of quinoline and indole derivatives

Quan Huang et al.

Summary: This paper describes a mild and efficient intramolecular oxidative cyclization reaction using substituted aromatic enamines and the C(sp(3))-H bond adjacent to nitrogen with alkynes or alkenes to produce multi-substituted quinolines and indoles, utilizing dioxygen as an oxidant. Visible light irradiation in combination with a simple and inexpensive copper catalyst enables functionalization of internal alkynes or alkenes via an intramolecular radical cyclization strategy without the need for additional photosensitizers. Preliminary mechanistic studies, including radical capture reactions, isotope labeling experiments, and fluorescence quenching study, have also been conducted.

ORGANIC CHEMISTRY FRONTIERS (2021)

Article Chemistry, Multidisciplinary

A competitive and highly selective 7-, 6-and 5-annulation with 1,3-migration through C-H and N-H - alkyne coupling

S. K. Ajarul et al.

CHEMICAL COMMUNICATIONS (2020)

Article Chemistry, Organic

New Friedel-Crafts strategy for preparing 3-acylindoles

Lian-Hua Li et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2018)

Review Chemistry, Multidisciplinary

Exploration of Visible-Light Photocatalysis in Heterocycle Synthesis and Functionalization: Reaction Design and Beyond

Jia-Rong Chen et al.

ACCOUNTS OF CHEMICAL RESEARCH (2016)

Article Chemistry, Multidisciplinary

Synthesis of N-Containing Heterocyclic Compounds Using Visible-light Photoredox Catalysis

Lei Zhou et al.

CHEMICAL RECORD (2016)

Article Chemistry, Multidisciplinary

Acylation of indoles via photoredox catalysis: a route to 3-acylindoles

Lijun Gu et al.

GREEN CHEMISTRY (2016)

Article Chemistry, Organic

Recent advances on the synthesis of acylindoles

Shun-Jiang Yao et al.

TETRAHEDRON LETTERS (2016)

Article Biochemistry & Molecular Biology

A Simple, Effective, Green Method for the Regioselective 3-Acylation of Unprotected Indoles

Phuong Hoang Tran et al.

MOLECULES (2015)

Article Chemistry, Multidisciplinary

A metal free domino synthesis of 3-aroylindoles via two sp3 C-H activation

Anupal Gogoi et al.

CHEMICAL COMMUNICATIONS (2014)

Review Biochemistry & Molecular Biology

Biomedical Importance of Indoles

Nagendra Kumar Kaushik et al.

MOLECULES (2013)

Review Chemistry, Multidisciplinary

Indoles in Multicomponent Processes (MCPs)

Morteza Shiri

CHEMICAL REVIEWS (2012)

Article Chemistry, Organic

Recent advances in indole syntheses: New routes for a classic target

Ruben Vicente

ORGANIC & BIOMOLECULAR CHEMISTRY (2011)

Review Chemistry, Multidisciplinary

Organocatalytic strategies for the asymmetric functionalization of indoles

Giuseppe Bartoli et al.

CHEMICAL SOCIETY REVIEWS (2010)

Review Chemistry, Organic

Biological Importance of the Indole Nucleus in Recent Years: A Comprehensive Review

Vikas Sharma et al.

JOURNAL OF HETEROCYCLIC CHEMISTRY (2010)

Article Chemistry, Organic

Palladium-Catalyzed Direct Alkynylation of C-H Bonds in Benzenes

Mamoru Tobisu et al.

ORGANIC LETTERS (2009)

Review Chemistry, Applied

Catalytic Synthesis of Indoles from Alkynes

Karolin Krueger et al.

ADVANCED SYNTHESIS & CATALYSIS (2008)

Review Chemistry, Multidisciplinary

Practical methodologies for the synthesis of indoles

Guy R. Humphrey et al.

CHEMICAL REVIEWS (2006)

Article Chemistry, Medicinal

Design, synthesis, and biological activity of potent and selective inhibitors of mast cell tryptase

CR Hopkins et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)

Article Chemistry, Multidisciplinary

Intramolecular C-N bond addition of amides to alkynes using platinum catalyst

T Shimada et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2004)