4.5 Article

Negishi Cross-Coupling in the Preparation of Benzyl Substituted Pyrrolo[2,3-d]pyrimidine Based CSF1R Inhibitors

Related references

Note: Only part of the references are listed.
Article Infectious Diseases

Halogenated Pyrrolopyrimidines with Low MIC on Staphylococcus aureus and Synergistic Effects with an Antimicrobial Peptide

Cecilie Elisabeth Olsen et al.

Summary: There is a global rise in antibiotic resistance, which burdens individuals and public healthcare systems, while drug development lags behind. Therefore, finding new ways of treating bacterial infections, such as identifying new agents or combinations of drugs, is crucial. Combination therapy based on agents with different modes of action can reduce the development of resistance.

ANTIBIOTICS-BASEL (2022)

Review Biochemistry & Molecular Biology

The M-CSF receptor in osteoclasts and beyond

Se Hwan Mun et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2020)

Article Chemistry, Medicinal

Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach

Jonas Lategahn et al.

JOURNAL OF MEDICINAL CHEMISTRY (2020)

Article Biochemistry & Molecular Biology

Potent and selective EGFR inhibitors based on 5-aryl-7H-pyrrolopyrimidin-4-amines

Ann Christin Reiersolmoen et al.

BIOORGANIC CHEMISTRY (2019)

Article Chemistry, Multidisciplinary

Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S

Jonas Lategahn et al.

CHEMICAL SCIENCE (2019)

Article Biochemistry & Molecular Biology

What Makes a Kinase Promiscuous for Inhibitors?

Sonya M. Hanson et al.

CELL CHEMICAL BIOLOGY (2019)

Article Medicine, Research & Experimental

Anti-tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC-dependent vulnerability

Kenichi Iwai et al.

EMBO MOLECULAR MEDICINE (2018)

Article Chemistry, Medicinal

Identification of fused pyrimidines as interleukin 17 secretion inhibitors

Ann Christin Reiersolmoen et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)

Article Multidisciplinary Sciences

High co-expression of IL-34 and M-CSF correlates with tumor progression and poor survival in lung cancers

Muhammad Baghdadi et al.

SCIENTIFIC REPORTS (2018)

Article Biochemistry & Molecular Biology

Family-wide Structural Analysis of Human Numb-Associated Protein Kinases

Fiona J. Sorrell et al.

STRUCTURE (2016)

Review Immunology

The interaction of anticancer therapies with tumor-associated macrophages

Alberto Mantovani et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2015)

Article Medicine, General & Internal

Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

W. D. Tap et al.

NEW ENGLAND JOURNAL OF MEDICINE (2015)

Article Immunology

The journey from stem cell to macrophage

Mikael J. Pittet et al.

YEAR IN IMMUNOLOGY: MYELOID CELLS AND INFLAMMATION (2014)

Review Oncology

Macrophage Regulation of Tumor Responses to Anticancer Therapies

Michele De Palma et al.

CANCER CELL (2013)

Review Multidisciplinary Sciences

Macrophage biology in development, homeostasis and disease

Thomas A. Wynn et al.

NATURE (2013)

Article Chemistry, Organic

Nickel-catalyzed Negishi cross-couplings of 6-chloropurines with organozinc halides at room temperature

Dong-Chao Wang et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

Activation State-Dependent Binding of Small Molecule Kinase Inhibitors: Structural Insights from Biochemistry

Lisa M. Wodicka et al.

CHEMISTRY & BIOLOGY (2010)

Article Multidisciplinary Sciences

The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

Cai-Hong Yun et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Chemistry, Organic

Convenient titration method for organometallic zinc, magnesium, and lanthanide reagents

A Krasovskiy et al.

SYNTHESIS-STUTTGART (2006)