4.7 Article

Antioxidant defense enzymes in multiple sclerosis: A 5-year follow-up study

Related references

Note: Only part of the references are listed.
Article Neurosciences

Oxidized phosphatidylcholines found in multiple sclerosis lesions mediate neurodegeneration and are neutralized by microglia

Yifei Dong et al.

Summary: Oxidized phosphatidylcholines (OxPCs) found in MS lesions are potent drivers of neurodegeneration, with microglia ameliorating the effects by neutralizing OxPCs that kill neurons and oligodendrocytes. Depletion of microglia exacerbates neurodegeneration in OxPC lesions, while enhancing microglia-mediated OxPC clearance via TREM2 could help prevent neurodegeneration in MS.

NATURE NEUROSCIENCE (2021)

Article Biochemistry & Molecular Biology

Decreased Cerebrospinal Fluid Antioxidative Capacity Is Related to Disease Severity and Progression in Early Multiple Sclerosis

Margarete M. Voortman et al.

Summary: The study revealed that decreased CSF AOC in MS patients was associated with increased disability and clinical disease activity. However, no correlations with MRI metrics were found. This suggests a need for further investigation into the role of AOC in the progression of MS.

BIOMOLECULES (2021)

Review Chemistry, Medicinal

Remyelination Pharmacotherapy Investigations Highlight Diverse Mechanisms Underlying Multiple Sclerosis Progression

George S. Melchor et al.

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2019)

Article Clinical Neurology

The NRF2 pathway as potential biomarker for dimethyl fumarate treatment in multiple sclerosis

Anna Hammer et al.

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2018)

Review Biochemistry & Molecular Biology

Transcriptional Regulation by Nrf2

Claudia Tonelli et al.

ANTIOXIDANTS & REDOX SIGNALING (2018)

Article Clinical Neurology

Serum Neurofilament Light: A Biomarker of Neuronal Damage in Multiple Sclerosis

Giulio Disanto et al.

ANNALS OF NEUROLOGY (2017)

Review Medicine, Research & Experimental

Oxidative stress-related biomarkers in multiple sclerosis: a review

Richard Ibitoye et al.

BIOMARKERS IN MEDICINE (2016)

Review Neurosciences

Oxidative stress in multiple sclerosis: Central and peripheral mode of action

Kim Ohl et al.

EXPERIMENTAL NEUROLOGY (2016)

Article Biochemistry & Molecular Biology

Protective associations of HDL with blood-brain barrier injury in multiple sclerosis patients

Kelly Fellows et al.

JOURNAL OF LIPID RESEARCH (2015)

Article Clinical Neurology

Apolipoproteins are associated with new MRI lesions and deep grey matter atrophy in clinically isolated syndromes

Richard W. Browne et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2014)

Review Clinical Neurology

Defining the clinical course of multiple sclerosis The 2013 revisions

Fred D. Lublin et al.

NEUROLOGY (2014)

Review Biochemistry & Molecular Biology

Role of peroxisomes in ROS/RNS-metabolism: Implications for human disease

Marc Fransen et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2012)

Article Clinical Neurology

Diagnostic Criteria for Multiple Sclerosis: 2010 Revisions to the McDonald Criteria

Chris H. Polman et al.

ANNALS OF NEUROLOGY (2011)

Article Clinical Neurology

Oxidative damage in multiple sclerosis lesions

Lukas Haider et al.

BRAIN (2011)

Review Pharmacology & Pharmacy

Cytochrome P450 enzymes in the brain: emerging evidence of biological significance

Charmaine S. Ferguson et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2011)

Article Clinical Neurology

Paraoxonase 1 activity in different types of multiple sclerosis

A. Jamroz-Wisniewska et al.

MULTIPLE SCLEROSIS JOURNAL (2009)

Article Biotechnology & Applied Microbiology

Analytical and biological variation of biomarkers of oxidative stress during the menstrual cycle

Richard W. Browne et al.

BIOMARKERS (2008)

Article Biochemistry & Molecular Biology

Severe oxidative damage in multiple sclerosis lesions coincides with enhanced antioxidant enzyme expression

J. van Horssen et al.

FREE RADICAL BIOLOGY AND MEDICINE (2008)

Review Biochemistry & Molecular Biology

The role of oxidative stress and NADPH oxidase in cerebrovascular disease

Sophocles Chrissobolis et al.

TRENDS IN MOLECULAR MEDICINE (2008)

Review Biochemistry & Molecular Biology

Antioxidant and cytoprotective properties of high-density lipoproteins in vascular cells

Anne Negre-Salvayre et al.

FREE RADICAL BIOLOGY AND MEDICINE (2006)

Article Endocrinology & Metabolism

Current understanding of the metabolism and biological actions of HDL

A von Eckardstein et al.

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2005)

Review Biochemistry & Molecular Biology

Mitochondria, oxidants, and aging

RS Balaban et al.

Article Biochemistry & Molecular Biology

Paraoxonases 1, 2, and 3, oxidative stress, and macrophage foam cell formation during atherosclerosis development

M Aviram et al.

FREE RADICAL BIOLOGY AND MEDICINE (2004)