☆ 4.5 Article

Impact of dapagliflozin on cardiac remodelling in patients with chronic heart failure: the DAPA-MODA study

EUROPEAN JOURNAL OF HEART FAILURE (2023)

Related references

Note: Only part of the references are listed.

Article Medicine, General & Internal

The effect of sodium-glucose cotransporter-2 inhibitors on cardiac structure remodeling and function: A meta-analysis of randomized controlled trials

Gang Fan et al.

Summary: This study conducted a meta-analysis on published randomized controlled trials and found that SGLT2 inhibitors, especially empagliflozin, have a significant effect on reversing cardiac remodeling in patients with heart failure. It may be a potentially promising agent in clinical practice.

EUROPEAN JOURNAL OF INTERNAL MEDICINE (2023)

Add to Collection

Article Cardiac & Cardiovascular Systems

Empagliflozin and Left Ventricular Remodeling in People Without Diabetes: Primary Results of the EMPA-HEART 2 CardioLink-7 Randomized Clinical Trial

Kim A. Connelly et al.

Summary: This study aimed to evaluate the effect of sodium-glucose cotransporter 2 inhibition with empagliflozin on left ventricular mass in individuals without diabetes or significant heart failure. The results showed that after 6 months of treatment with empagliflozin, there was no significant reduction in left ventricular mass index. The findings suggest that empagliflozin may not have meaningful benefits on cardiac remodeling in this population.

CIRCULATION (2023)

Add to Collection

Article Cardiac & Cardiovascular Systems

2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC

Theresa A. McDonagh et al.

Summary: All experts involved in the development of the guidelines have declared their interests, and the declarations have been compiled and published in a supplementary report. The report can be accessed on the ESC website. The supplementary data provide background information and detailed discussion of the data that form the basis for the guidelines.

EUROPEAN JOURNAL OF HEART FAILURE (2022)

Add to Collection

Review Cardiac & Cardiovascular Systems

Left atrial disease and left atrial reverse remodelling across different stages of heart failure development and progression: a new target for prevention and treatment

Riccardo M. Inciardi et al.

Summary: The left atrium is a dynamic chamber that can undergo changes in structure and function due to stressors and disease mechanisms. Left atrial disease is associated with poor outcomes and can contribute to the progression and clinical course of heart failure. Current evidence suggests that therapy may improve left atrial function and reverse left atrial remodelling, but more research is needed to understand the impact on patient prognosis and standardize clinically meaningful changes in left atrial measurements.

EUROPEAN JOURNAL OF HEART FAILURE (2022)

Add to Collection

Review Cardiac & Cardiovascular Systems

SGLT2 inhibitors and cardiac remodelling: a systematic review and meta-analysis of randomized cardiac magnetic resonance imaging trials

Nitish K. Dhingra et al.

Summary: Recent studies have shown the efficacy of SGLT2 inhibitors in preventing and treating heart failure by reversing left ventricular remodelling, as seen through the results of a systematic review and meta-analysis of RCTs comparing SGLT2 inhibitors versus placebo.

ESC HEART FAILURE (2022)

Add to Collection

Review Cardiac & Cardiovascular Systems

The Central Role of Left Atrium in Heart Failure

Myriam Carpenito et al.

Summary: In traditional cardiovascular medicine, the focus on the left ventricle has overshadowed the importance of the left atrium. Recent advances have shown that the left atrium plays a crucial role in various cardiovascular diseases, impacting symptoms, prognosis, and potential therapeutic targets.

FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Randomized Trial of Empagliflozin in Nondiabetic Patients With Heart Failure and Reduced Ejection Fraction

Carlos G. Santos-Gallego et al.

Summary: This study found that empagliflozin significantly improved left ventricular function and volumes, functional capacity, and quality of life in nondiabetic HFrEF patients, compared to placebo. The observations strongly support the role of sodium-glucose cotransporter 2 inhibitors in the treatment of HFrEF patients regardless of their glycemic status.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2021)

Add to Collection

Review Cardiac & Cardiovascular Systems

SGLT2 inhibitors and cardiac remodelling: a systematic review and meta-analysis of randomized cardiac magnetic resonance imaging trials

Nitish K. Dhingra et al.

Summary: Recent large RCTs have shown that SGLT2i treatment can reduce left ventricular mass as assessed by cMRI, suggesting a potential mechanism for preventing and treating heart failure.

ESC HEART FAILURE (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Prognostic Importance of NT-proBNP and Effect of Empagliflozin in the EMPEROR-Reduced Trial

Jr James L. Januzzi et al.

Summary: This study found that empagliflozin treatment reduced the risk of heart failure or renal events regardless of baseline NT-proBNP concentration in patients with heart failure.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Effect of Empagliflozin on Left Ventricular Volumes in Patients With Type 2 Diabetes, or Prediabetes, and Heart Failure With Reduced Ejection Fraction (SUGAR-DM-HF)

Matthew M. Y. Lee et al.

Summary: The study confirmed the effectiveness of sodium-glucose cotransporter 2 inhibitor empagliflozin in reducing left ventricular volumes in patients with HFrEF, favoring reverse left ventricular remodeling. This may be one of the mechanisms by which sodium-glucose cotransporter 2 inhibitors reduce heart failure hospitalization and mortality in HFrEF.

CIRCULATION (2021)

Add to Collection

Review Cardiac & Cardiovascular Systems

Left atrial function in heart failure with preserved ejection fraction: a systematic review and meta-analysis

Muhammad Shahzeb Khan et al.

EUROPEAN JOURNAL OF HEART FAILURE (2020)

Add to Collection

Review Cardiac & Cardiovascular Systems

Atrial Failure as a Clinical Entity JACC Review Topic of the Week

Felipe Bisbal et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2020)

Add to Collection

Article Cardiac & Cardiovascular Systems

A randomized controlled trial of dapagliflozin on left ventricular hypertrophy in people with type two diabetes: the DAPA-LVH trial

Alexander J. M. Brown et al.

EUROPEAN HEART JOURNAL (2020)

Add to Collection

Editorial Material Cardiac & Cardiovascular Systems

Left Atrial Strain Measurement A New Normal for Diastolic Assessment?

Goo-Yeong Cho et al.

JACC-CARDIOVASCULAR IMAGING (2020)

Add to Collection

Article Cardiac & Cardiovascular Systems

Dapagliflozin Effects on Biomarkers, Symptoms, and Functional Status in Patients With Heart Failure With Reduced Ejection Fraction The DEFINE-HF Trial

Michael E. Nassif et al.

CIRCULATION (2019)

Add to Collection

Article Medicine, General & Internal

Effect of Sacubitril-Valsartan vs Enalapril on Aortic Stiffness in Patients With Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial

Akshay S. Desai et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2019)

Add to Collection

Article Medicine, General & Internal

Association of Change in N-Terminal Pro-B-Type Natriuretic Peptide Following Initiation of Sacubitril-Valsartan Treatment With Cardiac Structure and Function in Patients With Heart Failure With Reduced Ejection Fraction

James L. Januzzi et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2019)

Add to Collection

Article Cardiac & Cardiovascular Systems

Left Atrial Reverse Remodeling Mechanisms, Evaluation, and Clinical Significance

Liza Thomas et al.

JACC-CARDIOVASCULAR IMAGING (2017)

Add to Collection

Article Cardiac & Cardiovascular Systems

Atrial reverse remodelling is associated with outcome of cardiac resynchronization therapyaEuro

Marielle Kloosterman et al.

EUROPACE (2016)

Add to Collection

Review Cardiac & Cardiovascular Systems

Global left atrial failure in heart failure

Filippos Triposkiadis et al.

EUROPEAN JOURNAL OF HEART FAILURE (2016)

Add to Collection

Article Cardiac & Cardiovascular Systems

Clinical Implications of Complete Left-Sided Reverse Remodeling With Cardiac Resynchronization Therapy A MADIT-CRT Substudy

Andrew Mathias et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2016)

Add to Collection

Article Cardiac & Cardiovascular Systems

Prognostic Importance of Changes in Cardiac Structure and Function in Heart Failure With Preserved Ejection Fraction and the Impact of Spironolactone

Amil M. Shah et al.

CIRCULATION-HEART FAILURE (2015)

Add to Collection

Article Cardiac & Cardiovascular Systems

Left Atrial Remodeling and Function in Advanced Heart Failure With Preserved or Reduced Ejection Fraction

Vojtech Melenovsky et al.

CIRCULATION-HEART FAILURE (2015)

Add to Collection

Article Medicine, General & Internal

Prediction of All-Cause Mortality by the Left Atrial Volume Index in Patients With Normal Left Ventricular Filling Pressure and Preserved Ejection Fraction

Dharmendrakumar A. Patel et al.

MAYO CLINIC PROCEEDINGS (2015)

Add to Collection

Article Cardiac & Cardiovascular Systems

Recommendations for Cardiac Chamber Quantification by Echocardiography in Adults: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging

Roberto M. Lang et al.

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING (2015)

Add to Collection

Review Cardiac & Cardiovascular Systems

Left atrial function in heart failure with impaired and preserved ejection fraction

Fang Fang et al.

CURRENT OPINION IN CARDIOLOGY (2014)

Add to Collection

Review Cardiac & Cardiovascular Systems

Left Atrial Size and Function Role in Prognosis

Brian D. Hoit

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2014)

Add to Collection

Article Cardiac & Cardiovascular Systems

The MUSIC Risk score: a simple method for predicting mortality in ambulatory patients with chronic heart failure

Rafael Vazquez et al.

EUROPEAN HEART JOURNAL (2009)

Add to Collection

Article Cardiac & Cardiovascular Systems

Left atrial enlargement and NT-proBNP as predictors of sudden cardiac death in patients with heart failure

Antoni Bayes-Genis et al.

EUROPEAN JOURNAL OF HEART FAILURE (2007)

Add to Collection

© Peeref 2019-2024. All rights reserved.