Bioinspired N-Oxide-Based Zwitterionic Polymer Brushes for Robust Fouling-Resistant Surfaces

Fouling-resistant surfaces are needed for various environmental applications. Inspired by superhydrophilic N-oxide-based osmolytes in saltwater fish, we demonstrate the use of a trimethylamine N-oxide (TMAO) analogue for constructing fouling-resistant surfaces. The readily synthesized N-oxide monomer of methacrylamide is grafted to filtration membrane surfaces by surface-initiated atom transfer radical polymerization (SI-ATRP). Successful grafting of the amine N-oxide brush layer as confirmed by material characterization endows the surface with increased hydrophilicity, reduced charge, and decreased roughness. Notably, the introduction of the N-oxide layer does not compromise transport properties, i.e., water permeability and water-salt selectivity. Moreover, the modified membrane exhibits improved antifouling properties with a lower flux decline (32.1%) and greater fouling reversibility (18.55%) than the control sample (45.4% flux decline and 3.26% fouling reversibility). We further evaluate foulant-membrane interaction using surface plasmon resonance (SPR) to relate the reduced fouling tendency to the synergic effects of surface characteristic changes after amine N-oxide modification. Our results demonstrate the promise and potential of the N-oxide-based polymer brushes for the design of fouling resistance surfaces for a variety of emerging environmental applications.

Automated summary

Inspired by osmolytes in saltwater fish, a trimethylamine N-oxide (TMAO) analog is used to construct fouling-resistant surfaces. The N-oxide monomer of methacrylamide is grafted onto filtration membrane surfaces using atom transfer radical polymerization. The modified membrane shows improved hydrophilicity, reduced charge, and decreased roughness without compromising water permeability and water-salt selectivity. The N-oxide-based polymer brushes have the potential for designing fouling-resistant surfaces for various environmental applications.