Recent trends in MXene-based material for biomedical applications

MXene is a magical class of 2D nanomaterials and emerging in many applications in diverse fields. Due to the multiple advantageous characteristics of its fundamental components, such as structural, physicochemical, op-tical, and occasionally even biological characteristics. However, it is limited in the biomedical industry due to poor physiological stability, decomposition rate, and lack of controlled and sustained drug release. These limi-tations can be overcome when MXene forms composites with other 2D materials. The efficiency of pure MXene in biomedicine is inferior to that of MXene-based composites. The availability of functionality on the exterior part of MXene has a key role in the modification of their surface and their characteristics. This review provides an extensive discussion on the synthesizing of MXene and the role of the surface functionalities on the efficiency of MXene. In addition, a detailed discussion of the biomedical applications of MXene, including antibacterial ac-tivity, regenerative medicine, CT scan capability, drug delivery, diagnostics, MRI and biosensing capability. Furthermore, an outline of the future problems and challenges of MXene-based materials for biomedical appli-cations was narrated. Thus, these salient features showcase the potential of MXene-based material and will be a breakthrough in biomedical applications in the near future.

Automated summary

MXene is a magical class of 2D nanomaterials with various advantageous characteristics, but its application in the biomedical industry is limited due to poor physiological stability and lack of controlled drug release. These limitations can be overcome by forming composites with other 2D materials. The surface functionalities of MXene play a crucial role in modifying its characteristics. This review discusses MXene synthesis, the role of surface functionalities, and its applications in biomedicine, including antibacterial activity, regenerative medicine, CT scan capability, drug delivery, diagnostics, MRI, and biosensing capability. The potential of MXene-based materials in biomedical applications is highlighted along with future challenges.