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Environmental Sciences
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Review
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Summary: In this study, an electrochemical sensor was developed for sensitive detection of dopamine using a novel COF-based nanocomposite called COF/Pt/MWCNT-COOH. The nanocomposite possesses a large specific surface area, excellent electrical conductivity, and high catalytic activity, thus expanding the application of COFs in the field of electrochemical sensing.
CHEMICAL COMMUNICATIONS
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Qi Huang et al.
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JOURNAL OF MATERIALS CHEMISTRY A
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Review
Pharmacology & Pharmacy
Peter Lees et al.
Summary: The evolution of antimicrobial drug (AMD) use in animals over the past eight decades has brought about revolutionary outcomes, with reports on various uses, misuses, and abuses increasing exponentially. While the treatment of animal diseases using AMDs will continue, it is crucial for it to be sustainable within the One Health paradigm and evolve towards more prudent, rational therapeutic uses. This review not only acknowledges concerns about antimicrobial resistance but also highlights the positive aspects and research-based advances resulting from the use of AMDs.
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS
(2021)
Article
Chemistry, Analytical
Mengjuan Kong et al.
Summary: In this study, the COF-300-AR was used as a catalyst to significantly increase the CL intensity of the luminol system in alkaline solution. A sensitive CL sensing method for detecting serotonin was successfully established based on the quenching efficiency of the luminol-COF-300-AR system. The method showed a linear response to serotonin concentration and was successfully applied for detection in rat serum samples.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Xueyan Yan et al.
Summary: This study successfully synthesized a multifunctional nanocomposite that can be used for detecting and treating Alzheimer's disease, releasing drugs upon near-infrared irradiation, inhibiting amyloid aggregation and degrading fibrils, as well as alleviating amyloid-induced oxidative stress and neural apoptosis.
ANALYTICAL CHEMISTRY
(2021)
Review
Chemistry, Multidisciplinary
Yidong Zou et al.
Summary: Mesoporous biomaterials as nanocarriers show great potential in drug-targeted therapy, becoming a hot topic in interdisciplinary research. Understanding assembly mechanisms, functionalization methods, and the impact of physicochemical parameters on DDS application will contribute to significant advancements in disease therapeutics.
ADVANCED MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Lu Zhang et al.
Summary: The study presents a high-efficiency peroxidase mimic MOF@COF nanozyme, utilizing the interaction between MOFs and COFs to achieve enhanced bacterial inhibition.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Biophysics
Huihui Liang et al.
Summary: This study utilized multienzyme microcapsules (enzymes@COF) containing glucose oxidase, horseradish peroxidase and acetylcholinesterase to construct an electrochemical biosensor with successful results. The 600 nm-sized cavity allowed for free conformation expansion of enzymes, while the COF shell provided good chemical stability and protection against external harsh environments. Additionally, the specific catalytic substrates of the enzymes could be infiltrated into the microcapsule through the pores of the COF shell.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Medicine, Research & Experimental
Andres Rubiano et al.
Summary: The study characterized the reproducibility of liver microphysiological systems (MPSs) in predicting hepatic drug effects through experiments on drug toxicity, metabolism, and intracellular accumulation. The results demonstrated that the liver MPS can reliably produce consistent experimental outcomes for drug evaluation applications, showing better stability and functionality compared to other culture platforms. The study also provided general considerations and recommendations for using liver MPSs in drug development.
CTS-CLINICAL AND TRANSLATIONAL SCIENCE
(2021)
Article
Biochemical Research Methods
Ruben F. Kranenburg et al.
Summary: Handheld Raman spectroscopy is a promising technique for rapid on-site detection of drugs of abuse, with the study evaluating the performance of a commercial handheld Raman spectrometer for cocaine detection showing a high true positive rate of 97.5% based on case sample analysis. The technique demonstrated high selectivity for Raman peaks specific to cocaine, with the potential for applicability in law enforcement and forensic investigations.
DRUG TESTING AND ANALYSIS
(2021)
Article
Environmental Sciences
Daniel Cerveny et al.
Summary: Through analyzing the plasma of wild fish from multiple countries, it was found that some pharmaceuticals exceeded 10% of the therapeutic plasma concentration in fish, including drugs that target the central nervous system like flupentixol, haloperidol, and risperidone. This not only highlights pharmaceuticals of environmental concern, but also emphasizes the importance of monitoring internal drug levels in aquatic wildlife.
ENVIRONMENT INTERNATIONAL
(2021)
Review
Chemistry, Inorganic & Nuclear
Miao He et al.
Summary: This article introduces the magnetic composites formed by magnetic nanoparticles and covalent organic frameworks, which have the potential for rapid magnetic separation and high chemical stability in environmental remediation and biotechnology applications. The classification, characteristics, synthesis methods, and application areas of MCOFs composites are detailed, providing a theoretical basis for future synthesis and design.
COORDINATION CHEMISTRY REVIEWS
(2021)
Review
Chemistry, Inorganic & Nuclear
Xiansheng Zhang et al.
Summary: Zirconium (Zr) based metal organic frameworks (Zr-MOFs) materials have shown increasing interest in the field of photocatalysis due to their large surface area, ordered porous structure, and excellent water-tolerant properties. These materials have been reported to exhibit excellent photocatalytic performance and are applied in various areas such as water splitting, carbon dioxide reduction, organic pollutant removal, and Cr(VI) reduction, with detailed mechanisms of these processes being described. Future developments and challenges of Zr-MOFs photocatalyst are also discussed.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Analytical
Pu Wu et al.
Summary: The newly synthesized MOF@MOF compound (NUZ-8) composed of NH2-UiO-66 and ZIF-8 with the structure modifier PVP showed unique polyhedron shape, high specific surface area, and excellent fluorescence properties. NUZ-8, used as a probe for the rapid optical detection of QCT, demonstrated outstanding selectivity and sensitivity, with wide linear range, low detection limit, and acceptable recoveries in red wine samples. This polyhedral composite provides guidance for enhancing chemical sensing and instant determination of drugs using IEGM.
Article
Engineering, Biomedical
Gyunggyu Lee et al.
Summary: Advances in pluripotent stem cell technology have led to the efficient and reproducible generation of hepatocyte-like cell spheroids in various sizes using microwell culture platforms. These spheroids show high expressions of hepatic marker genes, enhanced drug-metabolizing activity, and increased sensitivity to hepatotoxicants compared to traditional hepatocytes. This imaging-based toxicity screening system holds promise for predicting drug-induced hepatotoxicity in the early stages of drug discovery.
Article
Chemistry, Multidisciplinary
Leisan Gilmanova et al.
Summary: The synthesis of chemically stable two-dimensional imine covalent organic frameworks DUT-175 and DUT-176 has yielded structures with remarkable porosity and stability, making them ideal for indoor humidity control applications. Their complex conjugated pi system allows for reversible pH-dependent protonation and charge transfer, while the water vapor adsorption isotherms exhibit a sigmoidal shape with a steep adsorption step, confirming their suitability for humidity control.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Agricultural Engineering
Deqing Wang et al.
Summary: The study successfully immobilized Rha enzyme on magnetic MOFs for rutin hydrolysis, achieving higher activity, lower K-m value, and improved reusability. This indicates that magnetic MOF-immobilized enzymes are feasible biocatalysts for converting low water-soluble flavonoids.
BIORESOURCE TECHNOLOGY
(2021)
Article
Biophysics
Lanting Qian et al.
Summary: The rapid growth of the pharmaceutical industry due to increasing human population has led to the need for advanced nanomaterial-based electrochemical sensors and biosensors for monitoring pharmaceutical pollutants. This review article surveys state-of-the-art sensors for detecting significant pharmaceutical compounds and highlights strategies for developing high-performance sensors tailored toward specific pharmaceuticals.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Analytical
Qixia Guan et al.
Summary: A novel covalent organic framework was prepared and utilized to fabricate an electrochemical sensing platform with high performance for sensitive and selective detection of theophylline and caffeine simultaneously. The platform showed low detection limits, wide linear ranges, and successful application in real sample analyses.
Article
Chemistry, Analytical
Mater H. Mahnashi et al.
Summary: A sensitive and selective molecular imprinted polymeric network (MIP) electrochemical sensor was developed for the determination of anti-cancer drug oxaliplatin (OXAL). The sensor showed outstanding sensitivity, selectivity, reproducibility, and stability, with optimized fabrication processes and orthogonal design techniques. This MIP-based sensor opens up new possibilities for the fabrication of similar sensors and biosensors.
Review
Chemistry, Analytical
Manuel David Peris-Diaz et al.
Summary: Chemometric methods are powerful tools used in analytical sciences, with applications that are continuously increasing. This review presents the most common chemometric tools and mathematical models used in recent research articles, highlighting trends and potential pitfalls for non-experts in the field. Bringing together mathematical models with experimental challenges can be highly beneficial for chemometricians.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Review
Chemistry, Analytical
Weixiang Li et al.
Summary: The monitoring of EC reactions by ambient mass spectrometry (AMS) provides structural information of analytes, potential for detecting short-lived intermediates, examining reaction mechanisms, and discovering new reactions, contributing significantly to fields including biological chemistry, electrocatalysis, organic synthesis or battery fabrication. Various designs of EC-coupled electrospray ionization-based AMS systems, addressing advantages, limitations, and proposed suggestions for future developments, are summarized in this review.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Multidisciplinary Sciences
Bin Zhao et al.
Summary: A concept of drug-free therapeutics is proposed to avoid toxic side effects of traditional drugs, and a Z-scheme SnS1.68-WO2.41 nanocatalyst is developed for near infrared (NIR)-photocatalytic generation of oxidative holes and hydrogen molecules to achieve high efficacy and low toxicity in cancer treatment.
NATURE COMMUNICATIONS
(2021)
Article
Environmental Sciences
Ahmad Reza Bagheri et al.
Summary: Covalent organic frameworks (COFs) are versatile materials with unique features such as high specific surface area and chemical-physical stability, making them suitable for treating pollutants in the environment. Researchers have started to focus on COFs as a viable alternative material. Through adsorption and degradation, COFs can effectively remove a wide variety of hazardous pollutants.
Article
Chemistry, Applied
Xiong-Xin Peng et al.
Summary: A highly selective and sensitive luminescent sensor for monitoring TBZ in oranges has been developed, showing broad linear range, low LOD and rapid response time. The method was successfully applied to detect TBZ in real orange samples, with good recoveries obtained.
Review
Chemistry, Multidisciplinary
Bingxin Li et al.
Summary: This article briefly introduces the recent developments in using nanomaterials such as silver nanoparticles, liposomes, and metal-organic frameworks to combat Candida albicans in antifungal applications, aiming to improve the bioavailability of antifungal drugs.
FRONTIERS IN CHEMISTRY
(2021)
Article
Chemistry, Analytical
Tianfeng Wan et al.
Summary: A novel magnetic solid-phase extraction method based on MOF-801 modified magnetic nanoparticles was developed for the extraction of preterm labor treatment drugs from human plasma, showing high extraction efficiency and low detection limits.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2021)
Article
Chemistry, Analytical
Ruijuan Zheng et al.
Summary: A core-shell material (UiO@TapbTp) has been developed for detecting nonsteroidal anti-inflammatory drugs by MALDI-TOF MS, showing improved enrichment ability and matrix performance. Pre-enrichment under optimized conditions significantly reduces the detection limits of drugs, with good recoveries in complex samples like saliva and environmental water.
Article
Chemistry, Physical
Yongyi Liu et al.
Summary: Glycosyl-functionalized metal organic framework-5 based porous carbon nanofibers were synthesized using MOF-5 and glucose, fabricated into an electrochemical sensor. The sensor showed successful detection of quercetin with high recovery rates, demonstrating its potential application in analytical chemistry.
SURFACES AND INTERFACES
(2021)
Article
Chemistry, Analytical
Wencui Liang et al.
Summary: A new sensor based on a Co-single-atomic-site catalyst was developed for accurate determination of levodopa concentration in human fluids. The sensor exhibited superior electrochemical response, with a linear range of 0.1-200 μM and a limit of detection of 0.033 μM, making it a promising tool for clinical treatment of Parkinson's disease.
Article
Chemistry, Analytical
Xin Sun et al.
Summary: A novel high electrocatalytic material was synthesized by incorporating bimetallic nanoparticles in a 2D porous COF, which was further used to construct an electrochemical sensor for the ultrasensitive determination of levodopa. The sensor showed improved analytical performance and stability, making it a promising tool for accurate detection of levodopa in actual samples.
Article
Chemistry, Analytical
Caoling Li et al.
Summary: The research successfully improved the detection sensitivity of malachite green using copper-based metal-organic frameworks, with a detection limit lower than the reported values. This method was validated in water samples and showed consistent results with high-performance liquid chromatography.
ANALYTICA CHIMICA ACTA
(2021)
Article
Biophysics
Sathish Panneer Selvam et al.
Summary: A sensor for detecting PT molecules was developed using electropolymerized molecularly imprinted polymer as the base matrix of the electrode, achieving higher sensitivity and stability.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Biochemistry & Molecular Biology
Xin Huang et al.
Summary: The study focused on in silico modeling of drug-induced ototoxicity, collecting a large dataset to develop a series of computational models, which performed well in external validation with high accuracy.
CHEMICAL BIOLOGY & DRUG DESIGN
(2021)
Article
Chemistry, Physical
Qixia Guan et al.
Summary: In this study, a novel COF material TF-Py COF was successfully prepared and utilized in combination with carbon materials and gold nanoparticles to construct an electrochemical sensing platform with high sensitivity and selectivity for the simultaneous detection of ACOP and 4-AP. This platform showed sensitive response, wide linear range, and low detection limits for both analytes, with successful applications in real sample detection.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Review
Environmental Sciences
Liming Yang et al.
Summary: This review discusses recent advances in electrochemical metal recovery techniques, aiming to target recycling heavy metal resources with minimize energy consumption, boost recovery efficiency, and realize commercial application.
ENVIRONMENT INTERNATIONAL
(2021)
Review
Environmental Sciences
Dan Li et al.
Summary: Anticancer drugs are commonly detected in aquatic ecosystems, with potential toxic effects on aquatic organisms, particularly crustaceans. More research is needed to identify appropriate chronic endpoints for risk assessment thresholds, better understand the mechanisms of action, potential multigenerational toxicity, and trophic transfer in ecosystems.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Chemistry, Applied
Vesen Atiroglu et al.
Summary: MOFs have been utilized for a variety of applications due to their high porosity and flexibility. In this study, alpha-amylase was successfully immobilized using ZIF-8 as a support, resulting in enhanced pH and thermal stability. The OLB/BSA@ZIF-8-alpha-amylase showed excellent long-term storage stability and reusability.
Article
Biochemical Research Methods
Amirhassan Amiri et al.
Summary: In this study, Cu-based metal-organic framework (MOF-199) was fabricated on stainless steel mesh through sol-gel procedure for extraction and quantification of NSAIDs from human plasma and water samples. By optimizing extraction conditions, linear calibration graphs and high correlation coefficients were achieved, with LODs ranging from 0.01 to 0.02 ng mL-1 for water samples and 0.03 to 0.1 ng mL-1 for plasma samples. The method showed good repeatability and relative recoveries between 93.6% to 99.6%.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Article
Engineering, Environmental
Anna Pappa et al.
Summary: This study aimed to investigate the effects of four biomaterials in the form of microplastics on the biochemical parameters of snail hemocytes. The results showed that all parameters tested in biomaterials-treated snails differed significantly from those in biomaterials-free snails, indicating the pro-oxidant potential of biomaterials and their impact on animals' physiology. Among the biomaterials, modified chitosan and PCL had the most significant effects, while chitosan was the least toxic.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Analytical
Yifei Xing et al.
Summary: A highly sensitive non-enzymatic salvianic acid A (SAA) electrochemical sensor was successfully fabricated by modifying HKUST-1@(RGO-MWCNT) on a glassy carbon electrode, with low detection limit, high sensitivity, and good repeatability and stability.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2021)
Article
Chemistry, Multidisciplinary
Liting Yang et al.
Summary: Zirconium-based metal-organic frameworks (Zr-MOFs) have garnered significant interest due to their stability, flexible structures, and unique functions. This study introduces a new Zr-MOF (PCN-625) with a csq topological net, featuring vertical porphyrin rings and one-dimensional channels with different diameters. PCN-625 demonstrates potential as a heterogeneous catalyst for selective cycloaddition reactions.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Sebastian T. Emmerling et al.
Summary: Covalent organic frameworks (COFs) with a pore size beyond 5 nm are rare in this field. By adjusting interlayer interactions, different stacking modes and effective pore sizes can be achieved, leading to increased structural control and stability in large-pore COFs.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Electrochemistry
Mohammad-Hadi Karimi-Harandi et al.
Summary: In this study, an electrochemical sensor based on Cu-BTC metal-organic frameworks was synthesized and designed for simultaneous determination of METO and META, achieving high sensitivity and low detection limits. Characterization techniques confirmed the excellent electrochemical properties and application potential of Cu-BTC MOF in real samples.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2021)
Article
Multidisciplinary Sciences
Liang Chen et al.
Summary: A universal strategy for the synthesis of monodisperse core-shell structured COF nanocomposites remains challenging. The authors have developed a versatile dual-ligand assistant strategy for interfacial growth of COFs on functional nanoparticles with various properties for potential applications in PDT and chemotherapeutic drug delivery. The core@shell structured nanocomposites exhibit controllable shell-thickness and uniformity without agglomeration, making them promising for NIR-activated PDT with deep tissue penetration.
NATURE COMMUNICATIONS
(2021)
Review
Nanoscience & Nanotechnology
Shuncheng Yao et al.
Summary: Covalent organic frameworks (COFs) are porous and crystalline materials with diverse characteristics, making them excellent candidate materials for biomedical applications such as drug delivery, diagnostic imaging, and disease therapy. The components, dimensions, and guest molecule loading into COFs have a great influence on their performance in various applications, requiring further investigation.
NANO-MICRO LETTERS
(2021)
Article
Multidisciplinary Sciences
Yitian Zhou et al.
Summary: Interindividual variability in drug response is a major concern, with variants affecting drug target binding pockets leading to differences in pharmacodynamics. A common BCHE variant conferring resistance to certain drugs can be overcome with specific derivatives, highlighting the importance of genetic drug target variability in personalized drug selection.
Article
Chemistry, Multidisciplinary
Sathyadevi Palanisamy et al.
Summary: In this study, a method for the in-situ growth of amine-functionalized iron-containing metal-organic frameworks on porous nickel foam was developed. The resulting material was utilized as an immunosensor for the specific recognition and detection of FSH, demonstrating high sensitivity and a low detection limit in buffered and serum solutions. The availability of specific functional groups on MOFs makes them a promising choice for molecular sensing applications with tagged biomolecules such as Ab-FSH.
Review
Chemistry, Multidisciplinary
Zheng Meng et al.
Summary: COFs, as a new class of materials, show great potential in advancing chemical detection with high sensitivity and selectivity. By harnessing the unique properties of COFs, different types of chemical detection systems can be developed for various analytes under different mechanisms.
CHEMICAL SOCIETY REVIEWS
(2021)
Article
Chemistry, Multidisciplinary
Sushil Kumar et al.
Summary: This study explores the use of green solvents to synthesize COFs, evaluating crystallinity and porosity to assess quality and identifying gamma-butyrolactone, para-cymene, and PolarClean as excellent green solvents. For the first time, the researchers successfully predicted the surface area and crystallinity of COFs using quantitative structure-property relationships and machine learning approaches.
Article
Chemistry, Multidisciplinary
Sandeep Kumar et al.
Summary: This study analyzed the influence of solvent and reaction conditions on the formation of Zn(II) MOFs, examining the structural differences and properties of two MOFs. The luminescence properties of the MOFs in different solvents were also explored, providing insights into their potential applications in various fields.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Inorganic & Nuclear
Rongrong Yuan et al.
Summary: The development of novel porous materials, MOFs and COFs, has provided new opportunities for electrochemical aptasensors in biosensing applications, amplifying response signals and improving sensing performance. These sensors have been widely applied in monitoring various ultra-trace analytes such as antibiotics, pesticides, and cancer markers.
DALTON TRANSACTIONS
(2021)
Review
Chemistry, Physical
Zibo Zhai et al.
Summary: This paper reviews the recent progress in MOF-derived electrocatalysts, focusing on the characterization of catalytically active sites, functional mechanisms, and performance validation of various reactions. The synthesis methods, including alloy and composite formation, edge-defect/oxygen vacancy engineering, as well as advanced characterization techniques and theoretical calculations are discussed. The paper also analyzes technical challenges and proposes further research directions for the development of practical MOF-derived electrocatalysts in the future.
JOURNAL OF MATERIALS CHEMISTRY A
(2021)
Article
Chemistry, Multidisciplinary
Akkapol Suea-Ngam et al.
Summary: The continued development of high-performance and cost-effective in vitro diagnostic tools is crucial for improving the treatment and control of infectious diseases. Moving beyond enzyme-mediated amplification assays in nucleic acid diagnostics will be essential in reducing diagnostic technology's time and complexity. Additionally, an emerging threat area where in vitro diagnostics will play a crucial role is antimicrobial resistance in bacterial infections.
Review
Materials Science, Multidisciplinary
Yang Li et al.
Summary: Metal-organic frameworks (MOFs) and covalent organic frameworks (COFs), which are porous crystalline materials, can be intermeshed into MOF/COF hybrids to enhance performance and extend applications.
Article
Chemistry, Multidisciplinary
Long Yu et al.
Summary: This study presents a dopamine detection method based on a multifunctional lanthanide metal-organic framework, which provides high sensitivity, wide linear response, excellent selectivity, and accurate quantification of dopamine in serum. The conversion of Cu@Eu-BTC into a paper microchip demonstrates good storage stability and enables point-of-care visual dopamine assay with smartphone-assisted portable detection device.
Review
Chemistry, Multidisciplinary
Yosuke Hara et al.
Summary: Designing spatial and architectural features across different scales is a crucial topic in materials science, with a focus on the effects of porous structures on mass transport phenomena. While significant progress has been made in traditional inorganic materials, such as ceramics, the mechanistic understanding of spatial features at the molecular level remains limited in the field of electrochemical reactions. Further research on well-defined architectures is essential for advancements in next-generation energy devices.
Review
Geriatrics & Gerontology
Maria Beatrice Zazzara et al.
Summary: Key points: ADRs are common in frail, multimorbid older adults on polypharmacy, leading to health burden and hospitalization. Age-related factors, such as changes in pharmacokinetics, multimorbidity, polypharmacy, and frailty, increase the risk of ADRs. A multidimensional approach combining pharmaceutical interventions and a global health evaluation can reduce the burden of ADRs in older adults.
EUROPEAN GERIATRIC MEDICINE
(2021)
Article
Chemistry, Physical
Austin M. Evans et al.
Summary: The study compared the thermal stability of ten 2D COFs and found that they generally undergo a two-step thermal degradation process. Boronate ester-linked COFs are generally more thermally stable than comparable imine-linked COFs, while smaller crystalline lattices are more robust to thermal degradation.
FARADAY DISCUSSIONS
(2021)
Review
Toxicology
Tomas Smutny et al.
Summary: The pregnane X receptor (PXR) is a key transcription factor known for regulating xenobiotic detoxification, but it is also involved in endogenous metabolism and various pathological states. Non-coding RNAs, especially microRNAs, have been shown to post-transcriptionally regulate PXR expression. In addition, PXR is controlled by multiple transcription factors and genetic polymorphisms, with long non-coding RNAs also playing a role in PXR expression regulation.
ARCHIVES OF TOXICOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Hua-Qing Yin et al.
ACCOUNTS OF CHEMICAL RESEARCH
(2020)
Review
Engineering, Electrical & Electronic
Mritunjaya Parashar et al.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2020)
Article
Nanoscience & Nanotechnology
Xin-Yao Wang et al.
ACS APPLIED MATERIALS & INTERFACES
(2020)
Article
Nanoscience & Nanotechnology
Peng Jin et al.
ACS APPLIED MATERIALS & INTERFACES
(2020)
Review
Chemistry, Multidisciplinary
Lilia S. Xie et al.
Article
Environmental Sciences
Bo Wu et al.
ENVIRONMENT INTERNATIONAL
(2020)
Article
Chemistry, Inorganic & Nuclear
Vijay Gupta et al.
INORGANIC CHEMISTRY
(2020)
Review
Nanoscience & Nanotechnology
Yujia Sun et al.
NANO-MICRO LETTERS
(2020)
Article
Nanoscience & Nanotechnology
Sathyadevi Palanisamy et al.
ACS APPLIED MATERIALS & INTERFACES
(2020)
Article
Chemistry, Multidisciplinary
Cheng Lu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2020)
Article
Biophysics
Sharad S. Upadhyay et al.
BIOSENSORS & BIOELECTRONICS
(2020)
Article
Chemistry, Analytical
Yao Xie et al.
Article
Electrochemistry
Roghayeh Asadpour Joghani et al.
JOURNAL OF APPLIED ELECTROCHEMISTRY
(2020)
Article
Chemistry, Multidisciplinary
Sandeep Kumar et al.
Article
Engineering, Environmental
Cong Zhang et al.
CHEMICAL ENGINEERING JOURNAL
(2020)
Review
Chemistry, Multidisciplinary
Sidi Chen et al.
FRONTIERS IN CHEMISTRY
(2020)
Review
Chemistry, Multidisciplinary
Frederik Haase et al.
CHEMICAL SOCIETY REVIEWS
(2020)
Review
Biochemistry & Molecular Biology
Andrea Locke et al.
Article
Chemistry, Analytical
Wencui Liang et al.
ANALYTICA CHIMICA ACTA
(2020)
Article
Chemistry, Analytical
Liuna Wei et al.
MICROCHEMICAL JOURNAL
(2020)
Review
Chemistry, Multidisciplinary
Hai-Yang Li et al.
CHEMICAL SOCIETY REVIEWS
(2020)
Review
Chemistry, Multidisciplinary
Rakesh Kumar Sharma et al.
MATERIALS HORIZONS
(2020)
Review
Environmental Sciences
Muhammad Bilal et al.
CURRENT OPINION IN ENVIRONMENTAL SCIENCE & HEALTH
(2020)
Article
Plant Sciences
Nina Heidary et al.
PHYSIOLOGIA PLANTARUM
(2019)
Article
Chemistry, Analytical
Yufeng Sun et al.
SENSORS AND ACTUATORS B-CHEMICAL
(2019)
Article
Multidisciplinary Sciences
Yaroslav V. Solovev et al.
SCIENTIFIC REPORTS
(2019)
Article
Environmental Sciences
Jie Li et al.
ENVIRONMENT INTERNATIONAL
(2019)
Article
Chemistry, Multidisciplinary
Xinyu Guan et al.
Article
Nanoscience & Nanotechnology
Abdul Khayum Mohammed et al.
ACS APPLIED MATERIALS & INTERFACES
(2019)
Article
Environmental Sciences
Lina Gunnarsson et al.
ENVIRONMENT INTERNATIONAL
(2019)
Article
Biophysics
Xionghui Ma et al.
BIOSENSORS & BIOELECTRONICS
(2019)
Review
Biophysics
Xianlong Zhang et al.
BIOSENSORS & BIOELECTRONICS
(2019)
Article
Environmental Sciences
Teresa I. A. Gouveia et al.
ENVIRONMENT INTERNATIONAL
(2019)
Article
Chemistry, Inorganic & Nuclear
Vijay Gupta et al.
DALTON TRANSACTIONS
(2019)
Review
Chemistry, Multidisciplinary
Dingxuan Ma et al.
CHINESE CHEMICAL LETTERS
(2018)
Review
Urology & Nephrology
Xin Xu et al.
NATURE REVIEWS NEPHROLOGY
(2018)
Review
Chemistry, Physical
Rijia Lin et al.
JOURNAL OF MATERIALS CHEMISTRY A
(2018)
Article
Chemistry, Analytical
Oliver Jonas et al.
Article
Biochemical Research Methods
Yuhong Song et al.
JOURNAL OF CHROMATOGRAPHY A
(2018)
Article
Chemistry, Analytical
Ting Zhang et al.
SENSORS AND ACTUATORS B-CHEMICAL
(2018)
Article
Chemistry, Physical
Michelina Catauro et al.
Review
Chemistry, Multidisciplinary
Patrick A. Julien et al.
Article
Medicine, Legal
Nor Aijratul Asikin Mohamad Shalan et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2017)
Review
Multidisciplinary Sciences
Christian S. Diercks et al.
Review
Chemistry, Multidisciplinary
Junwen Zhou et al.
CHEMICAL SOCIETY REVIEWS
(2017)
Article
Chemistry, Physical
Amir Reza Abbasi et al.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2016)
Review
Chemistry, Inorganic & Nuclear
Baiyan Li et al.
COORDINATION CHEMISTRY REVIEWS
(2016)
Article
Chemistry, Analytical
Xiao-Yu Xu et al.
SENSORS AND ACTUATORS B-CHEMICAL
(2016)
Review
Pharmacology & Pharmacy
Kenny Kong et al.
ADVANCED DRUG DELIVERY REVIEWS
(2015)
Article
Chemistry, Multidisciplinary
Huan-Ming Xiong
ADVANCED MATERIALS
(2013)
Review
Toxicology
Chanemougasoundharam Arunachalam et al.
TOXICOLOGY LETTERS
(2013)
Review
Cell Biology
RB Sekar et al.
JOURNAL OF CELL BIOLOGY
(2003)
