Related references
Note: Only part of the references are listed.Facile Synthesis of Polyfunctional Indole-Pyrido[2,3-d]Pyrimidine Hybrids Using Nickel-Incorporated Fluorapatite Encapsulated Iron Oxide Nanocatalyst and Study of Their Antibacterial Activities
Sahar Dastmard et al.
POLYCYCLIC AROMATIC COMPOUNDS (2022)
Synthesis of New Thiazole and Pyrazole Clubbed 1,2,3-Triazol Derivatives as Potential Antimycobacterial and Antibacterial Agents
Shivaji M. Jagadale et al.
POLYCYCLIC AROMATIC COMPOUNDS (2022)
An Overview of the Synthetic Route to the Marketed Formulations of Pyrimidine: A Review
Amit Kumar et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2022)
Elevated Levels of IL-33, IL-17 and IL-25 Indicate the Progression from Chronicity to Hepatocellular Carcinoma in Hepatitis C Virus Patients
Momen Askoura et al.
PATHOGENS (2022)
Targeting chalcone binding sites in living Leishmania using a reversible fluorogenic benzochalcone probe
Ariane S. Batista et al.
BIOMEDICINE & PHARMACOTHERAPY (2022)
Identification of a promising hit from a new series of pyrazolo [1,5-a] pyrimidine based compounds as a potential anticancer agent with potent CDK1 inhibitory and pro-apoptotic properties through a multistep in vitro assessment
Hossam R. Elgiushy et al.
BIOORGANIC CHEMISTRY (2022)
Discovery of Thieno[2,3-d]pyrimidine-based KRAS G 12D inhibitors as potential anticancer agents via combinatorial virtual screening
Ling Li et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022)
Design and synthesis of novel urea derivatives of pyrimidine-pyrazoles as anticancer agents
Purna Koteswara Rao Cherukumalli et al.
JOURNAL OF MOLECULAR STRUCTURE (2022)
Pyrazole Scaffolds: Centrality in Anti-Inflammatory and Antiviral Drug Design
Dipanjan Karati et al.
MEDICINAL CHEMISTRY (2022)
Synthesis and biological evaluation of aryl derivatives of isoxazole pyrazolo[1,5-a] pyrimidines as anticancer agents
Danayya Nayudu Bhogireddy et al.
SYNTHETIC COMMUNICATIONS (2022)
Novel heteroannulated chromeno[3′,2′:5,6]pyrido[2,3-d][1,2,4]triazolo[4,3-a] pyrimidines and chromeno[3′′,2′′:5′,6′]pyrido[2′,3′:4,5]pyrimido[2,1-c][1,2,4] triazines: Synthesis, characterization and antimicrobial evaluation
Esam S. Allehyani
SYNTHETIC COMMUNICATIONS (2022)
Synthesis and anticancer activities of diverse furo[2,3-d]pyrimidine and benzofuro[3,2-d]pyrimidine derivatives
Xiaoyu Tang et al.
SYNTHETIC COMMUNICATIONS (2022)
Anti-cancer effects of pyrazole-platinum(II) complexes combined with anti-MUC1 monoclonal antibody versus monotherapy in DLD-1 and HT-29 colon cancer cells
Katarzyna Supruniuk et al.
TRANSLATIONAL ONCOLOGY (2022)
Targeting tumor cells with pyrazolo[3,4-d] pyrimidine scaffold: A literature review on synthetic approaches, structure activity relationship, structural and target-based mechanisms
Mohamed A. Abdelgawad et al.
ARABIAN JOURNAL OF CHEMISTRY (2022)
Synthesis, characterization, DFT, QSAR, antimicrobial, and antitumor studies of some novel pyridopyrimidines
Zeinab Hussain et al.
JOURNAL OF MOLECULAR STRUCTURE (2022)
Design, synthesis and biological evaluation of aryl and hetero-aryl linked thieno[3,2-d]pyrimidine derivatives as anticancer agents
M Koteswaraiah et al.
Chemical Data Collections (2022)
Design, synthesis and antibacterial activity of novel pleuromutilin derivatives with thieno[2,3-d]pyrimidine substitution
Rongcai Ding et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022)
Exploration of 6-methyl-7-(Hetero)Aryl-7-Deazapurine ribonucleosides as antileishmanial agents
Cai Lin et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022)
Synthesis, antifungal activity and in vitro mechanism of novel 1-substituted-5-trifluoromethyl-1H-pyrazole-4-carboxamide derivatives
Jingxin Yang et al.
ARABIAN JOURNAL OF CHEMISTRY (2022)
Design and prediction of novel pyrazole derivatives as potential anti-cancer compounds based on 2D-QSAR study against PC-3, B16F10, K562, MDA-MB-231, A2780, ACHN and NUGC cancer cell lines
Fatima Ezzahra Bennani et al.
HELIYON (2022)
Design, Synthesis and Biological Evaluation of Substituted Amide Derivatives of Isoxazole-Thieno[2,3-d]pyrimidines as Anticancer Agents
Karunakar Chidella et al.
Chemical Data Collections (2022)
Pyrimidine-conjugated fluoroquinolones as new potential broad-spectrum antibacterial agents
Yi-Min Tan et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2022)
Design, synthesis and antitumor activity study of a gemcitabine prodrug conjugated with a HDAC6 inhibitor
Yongliang Li et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2022)
Design and synthesis of novel indole and indazole-piperazine pyrimidine derivatives with anti-inflammatory and neuroprotective activities for ischemic stroke treatment
Hongwei Wang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022)
Synthesis, structural, biocomputational modeling and antifungal activity of novel armed pyrazoles
Abderrahim Titi et al.
JOURNAL OF MOLECULAR STRUCTURE (2022)
Crystallographic study, biological assessment and POM/Docking studies of pyrazoles-sulfonamide hybrids (PSH): Identification of a combined Antibacterial/Antiviral pharmacophore sites leading to in-silico screening the anti-Covid-19 activity
Mohammed Chalkha et al.
JOURNAL OF MOLECULAR STRUCTURE (2022)
Synthesis, spectroscopic, anti-bacterial activity, molecular docking, ADMET, toxicity and DNA binding studies of divalent metal complexes of pyrazole-3-one azo ligand
Mahmood M. Salih et al.
JOURNAL OF MOLECULAR STRUCTURE (2022)
Synthesis, molecular modeling, ADMET and fastness studies of some quinoline encompassing pyrimidine azo dye derivatives as potent antimicrobial agents
Harsh D Trivedi et al.
Chemical Data Collections (2022)
Design and synthesis of 1,2,3-triazole incorporated pyrimidine-benzoxazole derivatives as anticancer agents
D.G.S. Sudhakar et al.
Chemical Data Collections (2022)
Novel 1,3-diaryl pyrazole derivatives bearing methylsulfonyl moiety: Design, synthesis, molecular docking and dynamics, with dual activities as anti-inflammatory and anticancer agents through selectively targeting COX-2
Ahmed M. M. Shaker et al.
BIOORGANIC CHEMISTRY (2022)
Design, synthesis and biological evaluation of spiroisoquinoline-pyrimidine derivatives as anticancer agents against MCF-7 cancer cell lines
Shruti Gupta et al.
RESULTS IN CHEMISTRY (2022)
Synthesis of 2,7-diarylpyrazolo [1,5-a] pyrimidine derivatives with antitumor activity. Theoretical identification of targets
Andres Ballesteros-Casallas et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY REPORTS (2022)
Synthesis, Characterization, Antitubercular and Anti-Inflammatory Activity of New Pyrazolo[3,4-d]Pyrimidines
Ravindra Kulkarni et al.
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING (2021)
Synthesis and anticancer evaluation of some new pyrazolo[3,4-d][1,2,3]triazin-4-ones, pyrazolo[1,5-a]pyrimidines, and imidazo[1,2-b]pyrazoles clubbed with carbazole
Samir Bondock et al.
JOURNAL OF HETEROCYCLIC CHEMISTRY (2021)
1, 2, 4-triazoles Clubbed Pyrimidine Compounds with Synthesis, Anti-microbial, Antituberculosis, Antimalarial, and Anti-protozoal Studies
Navin B. Patel et al.
LETTERS IN ORGANIC CHEMISTRY (2021)
Pyrazolo[3,4-d]pyrimidine-based dual EGFR T790M/HER2 inhibitors: Design, synthesis, structureeactivity relationship and biological activity as potential antitumor and anticonvulsant agents
Phoebe F. Lamie et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
Synthesis and antifungal activity of new hybrids thiazolo[4,5-d]pyrimidines with (1H-1,2,4)triazole
Svetlana V. Blokhina et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2021)
Design and synthesis of quinoline-pyrimidine inspired hybrids as potential plasmodial inhibitors
Francis Kayamba et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
Design, syntheses and antitumor activities evaluation of 1,5-diaryl substituted pyrazole secnidazole ester derivatives
Qing-Hu Teng et al.
JOURNAL OF HETEROCYCLIC CHEMISTRY (2021)
Design, Synthesis, In Vitro Anticancer Evaluation and Molecular Modelling Studies of 3,4,5-Trimethoxyphenyl-Based Derivatives as Dual EGFR/HDAC Hybrid Inhibitors
Tarek S. Ibrahim et al.
PHARMACEUTICALS (2021)
Synthesis, docking, machine learning and antiproliferative activity of the 6-ferrocene/heterocycle-2-aminopyrimidine and 5-ferrocene-1H-Pyrazole derivatives obtained by microwave-assisted Atwal reaction as potential anticancer agents
Eclair Venturini Filho et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2021)
New pyrimidine and pyrazole-based compounds as potential EGFR inhibitors: Synthesis, anticancer, antimicrobial evaluation and computational studies
Ismail M. M. Othman et al.
BIOORGANIC CHEMISTRY (2021)
Design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives bearing 1,3-thiazole moiety as novel anti-inflammatory EGFR inhibitors with cardiac safety profile
Salah A. Abdel-Aziz et al.
BIOORGANIC CHEMISTRY (2021)
Efficacy of SPG-ODN 1826 Nanovehicles in Inducing M1 Phenotype through TLR-9 Activation in Murine Alveolar J774A.1 Cells: Plausible Nano-Immunotherapy for Lung Carcinoma
Mohammed F. Aldawsari et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
An effective green one-pot synthesis of some novel 5-(thiophene-2-carbonyl)-6-(trifluoromethyl)pyrano[2,3-c]pyrazoles and 6-(thiophene-2-carbonyl)-7-(trifluoromethyl)pyrano[2,3-d]pyrimidines bearing chromone ring as anticancer agents
Tarik E. Ali et al.
SYNTHETIC COMMUNICATIONS (2021)
Six novel complexes based on 5-Acetoxy-1-(6-chloro-pyridin-2-yl)-1H-pyrazole-3-carboxylic acid methyl ester derivatives: Syntheses, crystal structures, and anti-cancer activity
Yanhui Qiao et al.
ARABIAN JOURNAL OF CHEMISTRY (2021)
Synthesis and biological evaluation of aryl sulfonyl linked isoxazol-(pyridin-4-yl)pyrazolo [1,5-a]pyrimidines as cytotoxicity agents
G. Sabita et al.
Chemical Data Collections (2021)
Discovery of [1,2,4]-triazolo [1,5-a]pyrimidine-7(4H)-one derivatives as positive modulators of GABAA1 receptor with potent anticonvulsant activity and low toxicity
Longjiang Huang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
Synthesis and molecular docking study of new pyrazole derivatives as potent anti-breast cancer agents targeting VEGFR-2 kinase
Dina H. Dawood et al.
BIOORGANIC CHEMISTRY (2020)
Synthesis and antitumor activity of some nitrogen heterocycles bearing pyrimidine moiety
Marwa H. Ahmed et al.
JOURNAL OF HETEROCYCLIC CHEMISTRY (2020)
Design, synthesis, molecular modeling, and biological evaluation of pyrazole-naphthalene derivatives as potential anticancer agents on MCF-7 breast cancer cells by inhibiting tubulin polymerization
Guangcheng Wang et al.
BIOORGANIC CHEMISTRY (2020)
Synthesis of some new functionalized pyrano[2,3-c]pyrazoles and pyrazolo[4′,3′:5,6] pyrano[2,3-d]pyrimidines bearing a chromone ring as antioxidant agents
Tarik E. Ali et al.
SYNTHETIC COMMUNICATIONS (2020)
Targeting Kinetoplastid and Apicomplexan Thymidylate Biosynthesis as an Antiprotozoal Strategy
Maria Valente et al.
CURRENT MEDICINAL CHEMISTRY (2019)
ZnO Nanoparticles Catalyst in the Synthesis of Bioactive Fused Pyrimidines as Anti-breast Cancer Agents Targeting VEGFR-2
Dina H. Dawood et al.
MEDICINAL CHEMISTRY (2019)
Synthesis, Docking Studies into CDK-2 and Anticancer Activity of New Derivatives Based Pyrimidine Scaffold and Their Derived Glycosides
Adel A. H. Abdel Rahman et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2019)
Synthesis of novel pyrimidine derivatives with (pyridin-3-ylmethyl)thio and phenylamino moieties and evaluation of their antifungal activity
Shi-Chun Wang et al.
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS (2018)
5,6-Dihydropyrimidine-1(2H)-carbothioamides: Synthesis, in vitro GABA-AT screening, anticonvulsant activity and molecular modelling study
Meeta Sahu et al.
BIOORGANIC CHEMISTRY (2018)
Synthesis, Structure Elucidation, and Biological Activities of Pyrazoles Against Human Lung and Hepatocellular Cancer
Ghada S. Masaret
JOURNAL OF HETEROCYCLIC CHEMISTRY (2018)
Design, Synthesis and Biological Evaluation of Pyrido[2,3-d] Pyrimidine Derivatives as Potential Anticancer Agents
Jamelah S. Al-Otaibi et al.
LETTERS IN DRUG DESIGN & DISCOVERY (2018)
Bax, Bcl-2, and Bax/Bcl-2 as prognostic markers in acute myeloid leukemia: are we ready for Bcl-2-directed therapy?
Bibi Kulsoom et al.
CANCER MANAGEMENT AND RESEARCH (2018)
Roles of Pyridine and Pyrimidine Derivatives as Privileged Scaffolds in Anticancer Agents
Supaluk Prachayasittikul et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2017)
Synthesis and anticonvulsant activity of some 2-pyrazolines derived from chalcones
Nagihan Beyhan et al.
ARABIAN JOURNAL OF CHEMISTRY (2017)
Eco-friendly Synthesis of Pyrido[2,3-d]pyrimidine Analogs and Their Anticancer and Tyrosine Kinase Inhibition Activities
Abeer M. El-Naggar et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2017)
The Natural Flavonoid Fisetin Inhibits Cellular Proliferation of Hepatic, Colorectal, and Pancreatic Cancer Cells through Modulation of Multiple Signaling Pathways
Mhmoud Youns et al.
PLOS ONE (2017)
Facile Microwave-assisted Synthesis of Various C5-modified Pyrimidine Pyranonucleosides as Potential Cytotoxic Antitumor Agents
Athina Dimopoulou et al.
CURRENT MICROWAVE CHEMISTRY (2017)
Synthesis, Biological Evaluation and Molecular Docking Studies of 4H-benzo[h]chromenes, 7H-benzo[h]chromeno[2,3-d]pyrimidines as Antitumor Agents
Ahmed H. Halawa et al.
LETTERS IN DRUG DESIGN & DISCOVERY (2016)
Novel pyrazole derivatives with oxa/thiadiazolyl, pyrazolyl moieties and pyrazolo[4,3-d]-pyrimidine derivatives as potential antimicrobial and anticancer agents
Hend N. Hafez et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
Synthesis of new thiazolo-celecoxib analogues as dual cyclooxygenase-2/15-lipoxygenase inhibitors: Determination of regio-specific different pyrazole cyclization by 2D NMR
Eman K. A. Abdelall et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)
Synthesis and evaluation of 5,6-disubstituted thiopyrimidine aryl aminothiazoles as inhibitors of the calcium-activated chloride channel TMEM16A/Ano1
Katarzyna A. Piechowicz et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2016)
Synthesis of Isoxazole Moiety Containing Thieno[2,3-d]pyrimidine Derivatives and Preliminarily in vitro Anticancer Activity (Part II)
Jianping Yong et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2015)
Novel pyrazole-5-carboxamide and pyrazole-pyrimidine derivatives: Synthesis and anticancer activity
Jing Bo Shi et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Synthesis, and structure-activity relationship for C(4) and/or C(5) thienyl substituted pyrimidines, as a new family of antimycobacterial compounds
Egor V. Verbitskiy et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Synthesis and Antitumor Activity of New Pyrimidine and Caffeine Derivatives
Ameen Ali Abu-Hashem et al.
LETTERS IN DRUG DESIGN & DISCOVERY (2015)
Synthesis of novel 5-methyl pyrazol-3-one derivatives and their in vitro cytotoxic evaluation
Pritam N. Dube et al.
MEDICINAL CHEMISTRY RESEARCH (2015)
Synthesis and anticonvulsant activity of some newer dihydro-pyrimidine-5-carbonitrile derivatives: Part II
Mohammad R. Ali et al.
JOURNAL OF TAIBAH UNIVERSITY MEDICAL SCIENCES (2015)
Design, Synthesis and Biological Evaluation of 5-Amino-1H-pyrazole-4-carboxamide Derivatives as Potential Antitumor Agents
Baowei Yang et al.
LETTERS IN DRUG DESIGN & DISCOVERY (2014)
Synthesis, characterization of new imidazoquinonyl chalcones and pyrazolines as potential anticancer and antioxidant agents
Dinesha et al.
MEDICINAL CHEMISTRY RESEARCH (2014)
Synthesis and Biological Evaluation of Some Novel Thieno[2,3-d] pyrimidine Derivatives as Potential Anti-inflammatory and Analgesic Agents
Alaa El-Tombary et al.
Medicinal Chemistry (2013)
Antimycobacterial activities of 5-alkyl (or halo)-3′-substituted pyrimidine nucleoside analogs
Naveen C. Srivastav et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Synthesis and evaluation of anticonvulsant and antidepressant activities of 5-alkoxytetrazolo[1,5-c]thieno[2,3-e]pyrimidine derivatives
Shi-Ben Wang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)
Synthesis, anticonvulsant and neurotoxicity evaluation of some new pyrimidine-5-carbonitrile derivatives
Mohammad Shaquiquzzaman et al.
SAUDI PHARMACEUTICAL JOURNAL (2012)
Synthesis, molecular docking and evaluation of thiazolyl-pyrazoline derivatives as EGFR TK inhibitors and potential anticancer agents
Peng-Cheng Lv et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Synthesis and biological evaluation of pyrimidine analogs of antimycobacterial purines
Matthew L. Read et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Inhibitors of the Purine Salvage Pathway: A Valuable Approach for Antiprotozoal Chemotherapy?
M. Berg et al.
CURRENT MEDICINAL CHEMISTRY (2010)
Synthesis, anticonvulsant and toxicity screening of newer pyrimidine semicarbazone derivatives
Ozair Alam et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2010)
Synthesis, antitrichinnellosis and antiprotozoal activity of some novel thieno[2,3-d]pyrimidin-4(3H)-ones containing benzimidazole ring
Anelia Ts. Mavrova et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2010)
New thiopyrazolo[3,4-d]pyrimidine derivatives as anti-mycobacterial agents
Lluis Ballell et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities
J. C. Reed
CELL DEATH AND DIFFERENTIATION (2006)
Discovery of N-(2-chloro-6-methylphenyl)-2-(6-(4-(2-hydroxyethyl)-piperazin-1-yl)-2-methylpyrimidin-4-ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays
LJ Lombardo et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Share Paper
