4.7 Article

Reversible Intramolecular Proton Transfer in Curcumin Crystals and Nonlinear Size Correlation

Related references

Note: Only part of the references are listed.
Article Chemistry, Applied

Concise behavior of Curcumin in water-ethanol: Critical Water Aggregation Percentage and multivariate analysis of protolytic equilibria

Christhian Irineu Dias Pereira et al.

Summary: Curcumin has pharmacological effects but poor absorption and low bioavailability in clinical trials due to its hydrophobic nature, leading to controversies in spectroscopic characterization and self-aggregation processes. The study found that in water-ethanol mixtures, monomers predominate at 50% water, while self-aggregation occurs above 75% water. Molecular modeling and chemometric analysis revealed the presence of dimers even at 30% water content.

DYES AND PIGMENTS (2022)

Article Chemistry, Multidisciplinary

A structural and optical study of curcumin and curcumin analogs

Pooya Tahay et al.

Summary: In this study, curcumin dye was extracted and purified from turmeric, and curcumin analogues with similar structures but different functional groups and extended pi electrons were synthesized. The chemical structures of these molecules were investigated and characterized using UV-Vis, H-1 NMR, and IR spectroscopies. The results showed that the electron-donating groups on the aryl rings of these molecules enhanced the absorption intensity and shifted lambda(max) towards lower energies. The conformation and structure of these molecules were found to vary in solution and on TiO2 anatase surfaces, and they could anchor on the TiO2 surface in different modes depending on the surface sites. The application of these molecules as dyes in dye-sensitized solar cells was also studied, and the best efficiency was observed for the dye A3, which had a strong electron-donating group on the para phenyl ring. The appropriate IPCE of the A3 dye at 460 nm demonstrated that the beta-dicarbonyl group is a suitable anchoring group for DSSC application.

JOURNAL OF THE IRANIAN CHEMICAL SOCIETY (2022)

Article Engineering, Biomedical

Keto form of curcumin derivatives strongly binds to Aβ oligomers but not fibrils

Daijiro Yanagisawa et al.

Summary: The study found that the keto form of curcumin derivative Shiga-Y51 shows strong binding activity for A beta oligomers, but has scant affinity for A beta fibrils. Imaging mass spectrometry revealed the blood-brain barrier permeability of Shiga-Y51 and its accumulation in the brain, making it a promising seed compound for developing imaging probes and therapeutic agents targeting A beta oligomers in Alzheimer's disease.

BIOMATERIALS (2021)

Review Pharmacology & Pharmacy

The potency of heterocyclic curcumin analogues: An evidence-based review

Fiona C. Rodrigues et al.

Summary: Curcumin, a potent phytochemical with multiple bioactivities, has limitations in stability, bioavailability, and metabolism, hindering its full therapeutic potential. Structural modifications, particularly at the diketo moiety, have shown promising results in enhancing the activity of curcumin analogues.

PHARMACOLOGICAL RESEARCH (2021)

Article Chemistry, Multidisciplinary

CURCUMIN-WHEY PROTEIN SOLID DISPERSION SYSTEM WITH IMPROVED SOLUBILITY AND CANCER CELL INHIBITORY EFFECT

Levente Racz et al.

Summary: A solid dispersion system containing a high amount of curcumin was prepared using whey protein concentrate by spray-drying method, showing an amorphous state with weak hydrogen bond interactions and a homogeneous microparticle morphology. The enhanced solubility of curcumin and promising antitumoral effects against skin melanoma cells suggest potential for further exploitation.

STUDIA UNIVERSITATIS BABES-BOLYAI CHEMIA (2021)

Review Chemistry, Medicinal

Structural Studies of β-Diketones and Their Implications on Biological Effects

Poul Erik Hansen

Summary: This paper briefly summarizes methods for determining the structure of beta-diketones, with a focus on NMR methods and density functional calculations. It discusses the tautomeric equilibria of beta-diketones in relation to biological effects and relevant physical parameters like acidity and solubility. The structure of a series of biologically active molecules, including usnic acids, tetramic and tetronic acids, o-hydroxydibenzoylmethanes, curcumines, lupulones, and hyperforines, is examined.

PHARMACEUTICALS (2021)

Article Chemistry, Physical

Solvation effect on photophysical and photochemical properties of mono-biotinylated curcumin

Chen-Chen Zhao et al.

Summary: This study compared the photophysical and photochemical properties of curcumin and mono-biotinylated curcumin in different solvents, revealing the significant influence of solvent on their properties, especially the impact of the H-bond solvent methanol on mbt-Cur.

CHEMICAL PHYSICS LETTERS (2021)

Article Chemistry, Medicinal

Curcumin analogs: synthesis and biological activities

Mahmood Khudhayer Oglah et al.

MEDICINAL CHEMISTRY RESEARCH (2020)

Review Biochemistry & Molecular Biology

Curcumin in Health and Diseases: Alzheimer's Disease and Curcumin Analogues, Derivatives, and Hybrids

Eirini Chainoglou et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Chemistry, Multidisciplinary

Solid-State 1H, 13C, and 17O NMR Characterization of the Two Uncommon Polymorphs of Curcumin

Yizhe Dai et al.

CRYSTAL GROWTH & DESIGN (2020)

Article Engineering, Chemical

Understanding stability relationships among three curcumin polymorphs

Komal Upendra Pandey et al.

ADVANCED POWDER TECHNOLOGY (2019)

Article Chemistry, Physical

Interplay between conformational and solvent effects in UV-visible absorption spectra: curcumin tautomers as a case study

Alessandra Puglisi et al.

PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2019)

Review Chemistry, Multidisciplinary

Unraveling the Detailed Mechanism of Excited-State Proton Transfer

Panwang Zhou et al.

ACCOUNTS OF CHEMICAL RESEARCH (2018)

Article Chemistry, Multidisciplinary

Capturing Elusive Polymorphs of Curcumin: A Structural Characterization and Computational Study

Maria A. Matlinska et al.

CRYSTAL GROWTH & DESIGN (2018)

Review Chemistry, Multidisciplinary

Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents

Adam C. Sedgwick et al.

CHEMICAL SOCIETY REVIEWS (2018)

Review Chemistry, Inorganic & Nuclear

Non-covalent interactions in the synthesis of coordination compounds: Recent advances

Kamran T. Mahmudov et al.

COORDINATION CHEMISTRY REVIEWS (2017)

Article Chemistry, Multidisciplinary

Acoustic Emission from Organic Martensites

Manas K. Panda et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Review Chemistry, Multidisciplinary

Excited-state intramolecular proton-transfer (ESIPT)-inspired solid state emitters

Vikas S. Padalkar et al.

CHEMICAL SOCIETY REVIEWS (2016)

Article Biochemistry & Molecular Biology

Radio-protective effect of some new curcumin analogues

Marwa G. El-Gazzar et al.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2016)

Article Chemistry, Multidisciplinary

Mechanically Flexible Organic Crystals Achieved by Introducing Weak Interactions in Structure: Supramolecular Shape Synthons

Gamidi Rama Krishna et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

Article Chemistry, Multidisciplinary

Solid-State Phase Transformations and Storage Stability of Curcumin Polymorphs

Alpana Ankush Thorat et al.

CRYSTAL GROWTH & DESIGN (2015)

Article Biochemistry & Molecular Biology

Curcumin derivatives as metal-chelating agents with potential multifunctional activity for pharmaceutical applications

Erika Ferrari et al.

JOURNAL OF INORGANIC BIOCHEMISTRY (2014)

Article Spectroscopy

The effect of the water on the curcumin tautomerism: A quantitative approach

Yana Manolova et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2014)

Review Chemistry, Multidisciplinary

Excited-state proton coupled charge transfer modulated by molecular structure and media polarization

Alexander P. Demchenko et al.

CHEMICAL SOCIETY REVIEWS (2013)

Review Chemistry, Multidisciplinary

Crystal engineering of topochemical solid state reactions

Kumar Biradha et al.

CHEMICAL SOCIETY REVIEWS (2013)

Article Pharmacology & Pharmacy

Chemical and Structural Features Influencing the Biological Activity of Curcumin

K. Indira Priyadarsini

CURRENT PHARMACEUTICAL DESIGN (2013)

Article Spectroscopy

Stabilization of diketo tautomer of curcumin by premicellar anionic surfactants: UV-Visible, fluorescence, tensiometric and TD-DFT evidences

Anisha Dutta et al.

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY (2013)

Article Chemistry, Physical

A small change in molecular structure, a big difference in the AIEE mechanism

Minmin Cai et al.

PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2012)

Article Chemistry, Multidisciplinary

New polymorphs of curcumin

Palash Sanphui et al.

CHEMICAL COMMUNICATIONS (2011)

Review Chemistry, Multidisciplinary

Aggregation-induced emission

Yuning Hong et al.

CHEMICAL SOCIETY REVIEWS (2011)

Review Chemistry, Multidisciplinary

Recent Experimental Advances on Excited-State Intramolecular Proton Coupled Electron Transfer Reaction

Cheng-Chih Hsieh et al.

ACCOUNTS OF CHEMICAL RESEARCH (2010)

Article Chemistry, Multidisciplinary

Supramolecular Catalysis in the Organic Solid State through Dry Grinding

Anatoliy N. Sokolov et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

Article Chemistry, Multidisciplinary

Theoretical study on the antioxidant activity of curcumin

You-Min Sun et al.

CHINESE JOURNAL OF CHEMISTRY (2010)

Article Chemistry, Multidisciplinary

A White-Light-Emitting Molecule: Frustrated Energy Transfer between Constituent Emitting Centers

Sanghyuk Park et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

Article Chemistry, Multidisciplinary

π-Conjugated aromatic enynes as a single-emitting component for white electroluminescence

Y Liu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

Article Chemistry, Physical

DFT and experimental studies of the structure and vibrational spectra of curcumin

TM Kolev et al.

INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY (2005)