Interactions between plant-derived antioxidants and cyclodextrins and their application for improving separation, detection, and food quality issues

Plant-derived antioxidants (PD-AOs) are important for food preservation, as well as for human health and nutrition. However, the poor chemical stability and water solubility of many PD-AOs currently limit their application as functional ingredients in foods and pharmaceuticals. Moreover, it is often difficult to isolate and detect specific antioxidants in multi-component systems, which again limits their potential in the food and medical industries. In this review, we highlight recent advances in the use of cyclodextrins (CDs) to overcome these limitations by forming simple, modified and competitive host-guest interactions with PD-AO. The host-guest properties of CDs can be used to enhance the separation efficiency of PD-AOs, as well as to improve their dispersion and stability in food systems. Moreover, the competitive complexation properties of CDs with target molecules can be used to selectively isolate PD-AOs from multi-component systems and develop detection technologies for PD-AOs. Overall, CD-antioxidant interactions have great potential for addressing isolation, detection, and food quality issues.

Automated summary

Plant-derived antioxidants (PD-AOs) play a crucial role in food preservation and human health. However, the current limitations of PD-AOs, such as poor chemical stability and water solubility, hinder their application in the food and pharmaceutical industries. This review discusses the use of cyclodextrins (CDs) to overcome these limitations by forming host-guest interactions with PD-AOs, improving their dispersion and stability in food systems, and selectively isolating them from multi-component systems. The CD-antioxidant interactions show great potential in addressing isolation, detection, and food quality issues.