Monomethyl branched-chain fatty acids-a pearl dropped in the ocean

As an emerging group of bioactive fatty acids, monomethyl branched-chain fatty acids (mmBCFAs) have sparked the interest of many researchers both domestically and internationally. In addition to documenting the importance of mmBCFAs for growth and development, there is increasing evidence that mmBCFAs are highly correlated with obesity and insulin resistance. According to previous pharmacological investigations, mmBCFAs also exhibit anti-inflammatory effects and anticancer properties. This review summarized the distribution of mmBCFAs, which are widely found in dairy products, ruminants, fish, and fermented foods. Besides, we discuss the biosynthesis pathway in different species and detection methods of mmBCFAs. With the hope to unveil their mechanisms of action, we recapitulated detailed the nutrition and health benefits of mmBCFAs. Furthermore, this study provides a thorough, critical overview of the current state of the art, upcoming difficulties, and trends in mmBCFAs.

Automated summary

As an emerging group of bioactive fatty acids, monomethyl branched-chain fatty acids (mmBCFAs) have attracted the interest of domestic and international researchers. They are not only important for growth and development, but also highly correlated with obesity and insulin resistance. Previous studies have shown that mmBCFAs exhibit anti-inflammatory and anticancer effects. This review provides a comprehensive summary of mmBCFAs' distribution, biosynthesis pathway, detection methods, and their nutrition and health benefits. It also critically examines the current state of the art, upcoming difficulties, and trends in mmBCFAs.