Journal
CLINICAL NUCLEAR MEDICINE
Volume 48, Issue 8, Pages 729-731Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/RLU.0000000000004737
Keywords
angiomyolipoma; FAPI; kidney; PET; tuberous sclerosis complex
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We report a case of tuberous sclerosis complex with multiple angiomyolipomas involving bilateral kidneys and an extrarenal retroperitoneal angiomyolipoma. The Ga-68-FAPI-04 PET/MRI showed that the extrarenal tumor and most of the renal tumors were positive, suggesting the consideration of angiomyolipomas in the differential diagnosis of FAPI-avid renal or extrarenal retroperitoneal lesions.
Extrarenal retroperitoneal angiomyolipomas are rare benign tumors that may mimic other benign or malignant retroperitoneal tumors. We describe Ga-68-FAPI-04 PET/MRI findings in a case of tuberous sclerosis complex with an extrarenal retroperitoneal angiomyolipoma and multiple angiomyolipomas involving bilateral kidneys. The extrarenal retroperitoneal angiomyolipoma and most of the renal angiomyolipomas were Ga-68-FAPI-04-avid. One left renal angiomyolipoma with extensive hemorrhage and fibrosis had no significant Ga-68-FAPI-04 uptake. Angiomyolipoma should be included in the differential diagnosis of FAPI-avid renal or extrarenal retroperitoneal lesions.
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