4.7 Article

Detection of synovial fluid LTF and S100A8 by chemiluminescence immunoassay for the diagnosis of periprosthetic joint infection

Related references

Note: Only part of the references are listed.
Review Orthopedics

Diagnosing Periprosthetic Joint Infection: a Scoping Review

Aaron Gazendam et al.

Summary: The purpose of this review is to provide an updated understanding of the current tests used for the diagnosis of periprosthetic joint infection (PJI) in total knee and hip arthroplasty. Despite the increasing number of diagnostic methods, diagnosing PJI remains challenging. A combination of clinical, serum, and synovial tests, as well as microbiologic and histologic examinations, are commonly used for diagnosis. Novel molecular and imaging studies may be beneficial for cases with uncertain diagnosis. Recently proposed stepwise diagnostic algorithms have shown high sensitivity and specificity. However, the lack of definitive tests to rule out infection makes the diagnosis of PJI challenging.

CURRENT REVIEWS IN MUSCULOSKELETAL MEDICINE (2022)

Article Orthopedics

Concomitant Hip and Knee Periprosthetic Joint Infection in Periprosthetic Fracture: Diagnostic Utility of Serum and Synovial Fluid Markers

Janna van den Kieboom et al.

Summary: The diagnostic performance of serum and synovial markers for detecting PJI in patients with periprosthetic fractures was lower compared to those with PJI alone. Using higher thresholds and combining all markers may improve the accuracy of diagnosis.

JOURNAL OF ARTHROPLASTY (2021)

Article Medical Laboratory Technology

Rapid and sensitive detection of L-FABP for prediction and diagnosis of acute kidney injury in critically ill patients by chemiluminescent immunoassay

Tao Sun et al.

Summary: The study developed an automated chemiluminescent immunoassay method for detecting L-FABP, showing excellent analytical sensitivity and a wide linear range. Results indicated that higher L-FABP concentrations were associated with an increased risk of AKI occurrence and progression. The rapid and sensitive detection method of L-FABP could potentially benefit patients as a predictive and diagnostic biomarker for AKI.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2021)

Article Medical Laboratory Technology

A quantitative detection of Cardiotrophin-1 in chronic heart failure by chemiluminescence immunoassay

Ying Ping et al.

Summary: The study developed a one-step paramagnetic particles-based chemiluminescence immunoassay for detecting plasma CT-1, demonstrating high sensitivity, wide linear range, acceptable precision, and applicable reproducibility. The method was also shown to be suitable for high-throughput detection of CT-1 in clinical inspection, with potential for clinical applications in the diagnosis, staging, and prognostic assessment of heart failure.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2021)

Article Orthopedics

Clinical characteristics and risk factors for culture-negative periprosthetic joint infections

Shintaro Watanabe et al.

Summary: This study found that a low serum white blood cell count is a risk factor for culture-negative periprosthetic joint infections (PJIs), but prior antimicrobial therapy is not. The results suggest that PJIs with lower levels of systemic inflammation are likely to be culture-negative.

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH (2021)

Article Orthopedics

Detecting Periprosthetic Joint Infection by Using Mass Spectrometry

Rui Li et al.

Summary: This study demonstrated the potential of mass spectrometry in diagnosing periprosthetic joint infection, with MNDA and PRTN3 identified as key markers for detecting PJI. Combining MNDA and PRTN3 in a predictive model showed a high diagnostic accuracy, and parallel reaction monitoring simplified the detection process while providing quantitative results.

JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME (2021)

Article Dentistry, Oral Surgery & Medicine

S100A8 and S100A9 in saliva, blood and gingival crevicular fluid for screening established periodontitis: a cross-sectional study

Hyun-Duck Kim et al.

Summary: This study compared the association and screening ability of S100A8 and S100A9 in saliva, blood, and gingival crevicular fluid for periodontitis status. Salivary S100A8 was significantly higher in established periodontitis, while GCF S100A8 and S100A9 were higher in no or initial periodontitis. Salivary S100A8 could be a potential diagnostic marker for established periodontitis.

BMC ORAL HEALTH (2021)

Article Biochemical Research Methods

Chemiluminescence imaging immunoassay for simultaneous determination of TBBPA-DHEE and TBBPA-MHEE in aquatic environments

Kun Zeng et al.

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2020)

Article Medical Laboratory Technology

Serological chemiluminescence immunoassay for the diagnosis of SARS-CoV-2 infection

Lijia Shao et al.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2020)

Article Dentistry, Oral Surgery & Medicine

Diagnostic and Prognostic ability of salivary MMP-9 and S100A8 for periodontitis

Hyun-Duck Kim et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2020)

Article Orthopedics

Meta-analysis in periprosthetic joint infection: a global bibliometric analysis

Cheng Li et al.

JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH (2020)

Article Biochemical Research Methods

A chemiluminescence immunoassay for the detection of NT-proBNP

Yu-Yan Chen et al.

ANALYTICAL BIOCHEMISTRY (2020)

Article Medical Laboratory Technology

A Rapid Quantitative Chemiluminescence Immunoassay for Vitamin B12 in Human Serum

Xiang Chen et al.

CLINICAL LABORATORY (2020)

Review Biochemistry & Molecular Biology

Lactoferrin: Major Physiological Functions and Applications

Liyuan Hao et al.

CURRENT PROTEIN & PEPTIDE SCIENCE (2019)

Article Medical Laboratory Technology

Evaluation of a newly developed chemiluminescence immunoassay for detecting cardiac troponin T

Jingkun Wang et al.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2018)

Review Immunology

S100A8/A9 in Inflammation

Siwen Wang et al.

FRONTIERS IN IMMUNOLOGY (2018)

Review Cell Biology

Calprotectin (S100A8/S100A9): a key protein between inflammation and cancer

Fatemeh Shabani et al.

INFLAMMATION RESEARCH (2018)