Amperometric Detection of Glucose Using a Bimetallic Polymeric Film on a Pencil Graphite Electrode

A non-enzymatic electrochemical sensor was to be developed for the detection of glucose by combining the features of a molecularly imprinted polymer, the high conductive nature of polyaniline, and hierarchical dendritic structures. To meet this aim, a bimetallic film-coated graphite electrode was electropolymerized in the presence of aniline monomers to obtain a glucose-imprinted bimetallic polymeric film-coated electrode. The parameters affecting the electrodeposition were optimized using Minitab 19.1 software, and the mechanism of electrooxidation of glucose on the electrode surface was proposed. Electrochemical and morphological characterization of the fabricated electrode revealed its sensitivity toward millimolar amounts of glucose and showed higher selectivity in the presence of interfering species.

Automated summary

A non-enzymatic electrochemical sensor was developed for glucose detection by combining molecularly imprinted polymer, polyaniline, and hierarchical dendritic structures. The electrodeposition parameters were optimized using Minitab 19.1 software, and the electrooxidation mechanism of glucose on the electrode surface was proposed. The fabricated electrode showed sensitivity towards millimolar amounts of glucose and higher selectivity in the presence of interfering species.