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Jessica N. Peoples et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2019)
Interventions targeted at oxidatively generated modifications of nucleic acids focused on urine and plasma markers
Emil List Larsen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2019)
TFEB protects nucleus pulposus cells against apoptosis and senescence via restoring autophagic flux
Gang Zheng et al.
OSTEOARTHRITIS AND CARTILAGE (2019)
Estrogen Deficiency Exacerbates Intervertebral Disc Degeneration Induced by Spinal Instability in Rats
Qi io Liu et al.
SPINE (2019)
Genetic Predisposition to Symptomatic Lumbar Disk Herniation in Pediatric and Young Adult Patients
Nicholas Theodore et al.
SPINE (2019)
Restoration of Autophagic Flux Rescues Oxidative Damage and Mitochondrial Dysfunction to Protect against Intervertebral Disc Degeneration
Liang Kang et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)
Cysteine Disulfides (Cys-ss-X) as Sensitive Plasma Biomarkers of Oxidative Stress
Xiaoyun Fu et al.
SCIENTIFIC REPORTS (2019)
NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis
Matthew Dodson et al.
REDOX BIOLOGY (2019)
Mitochondrial ROS promote macrophage pyroptosis by inducing GSDMD oxidation
Yufang Wang et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2019)
AMPK: guardian of metabolism and mitochondrial homeostasis
Sebastien Herzig et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
Targeting RAGE Signaling in Inflammatory Disease
Barry I. Hudson et al.
ANNUAL REVIEW OF MEDICINE, VOL 69 (2018)
Carnosine and advanced glycation end products: a systematic review
Ramin Ghodsi et al.
AMINO ACIDS (2018)
GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues
Matilde Maiorino et al.
ANTIOXIDANTS & REDOX SIGNALING (2018)
Resveratrol enhances matrix biosynthesis of nucleus pulposus cells through activating autophagy via the PI3K/Akt pathway under oxidative damage
Jinlou Gao et al.
BIOSCIENCE REPORTS (2018)
Role of mitochondrial ROS in the brain: from physiology to neurodegeneration
Plamena R. Angelova et al.
FEBS LETTERS (2018)
Honokiol alleviates the degeneration of intervertebral disc via suppressing the activation of TXNIP-NLRP3 inflammasome signal pathway
Pan Tang et al.
FREE RADICAL BIOLOGY AND MEDICINE (2018)
Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older Adults
Matthew J. Rossman et al.
HYPERTENSION (2018)
Melatonin resists oxidative stress-induced apoptosis in nucleus pulposus cells
Ruijun He et al.
LIFE SCIENCES (2018)
Proteome oxidative carbonylation during oxidative stress-induced premature senescence of WI-38 human fibroblasts
Marine Le Boulch et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2018)
The interplay between inflammation, oxidative stress, DNA damage, DNA repair and mitochondrial dysfunction in depression
Piotr Czarny et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2018)
The mitochondrially targeted antioxidant MitoQ protects the intestinal barrier by ameliorating mitochondrial DNA damage via the Nrf2/ARE signaling pathway
Qiongyuan Hu et al.
CELL DEATH & DISEASE (2018)
Sirt6 overexpression suppresses senescence and apoptosis of nucleus pulposus cells by inducing autophagy in a model of intervertebral disc degeneration
Jian Chen et al.
CELL DEATH & DISEASE (2018)
A retrospective study: Does cigarette smoking induce cervical disc degeneration?
Zhaoxiong Chen et al.
INTERNATIONAL JOURNAL OF SURGERY (2018)
Progress in Applications of Prussian Blue Nanoparticles in Biomedicine
Zhiguo Qin et al.
ADVANCED HEALTHCARE MATERIALS (2018)
Elevated levels of 8-oxoGuo and 8-oxodG in individuals with severe mental illness - An autopsy-based study
Martin Roest Christensen et al.
FREE RADICAL BIOLOGY AND MEDICINE (2018)
Protein aggregation - Mechanisms, detection, and control
Wei Wang et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2018)
Cellular senescence: Molecular mechanisms and pathogenicity
Wenqiang Wei et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2018)
Intervertebral Disk Degeneration and Repair (vol 80, pg S46, 2018)
James Dowdell et al.
NEUROSURGERY (2018)
17 beta-Estradiol inhibits intervertebral disc degeneration by down-regulating MMP-3 and MMP-13 and up-regulating type II collagen in a rat model
Sen Liu et al.
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2018)
Pkcδ Activation is Involved in ROS-Mediated Mitochondrial Dysfunction and Apoptosis in Cardiomyocytes Exposed to Advanced Glycation End Products (Ages)
Yao-Chih Yang et al.
AGING AND DISEASE (2018)
Sirtuin 3-dependent mitochondrial redox homeostasis protects against AGEs-induced intervertebral disc degeneration
Yu Song et al.
REDOX BIOLOGY (2018)
Matrine Attenuates D-Galactose-Induced Aging-Related Behavior in Mice via Inhibition of Cellular Senescence an Oxidative Stress
Kaiyue Sun et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
Estradiol Alleviates Intervertebral Disc Degeneration through Modulating the Antioxidant Enzymes and Inhibiting Autophagy in the Model of Menopause Rats
Lin-Yu Jin et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
Resveratrol attenuates high glucose-induced nucleus pulposus cell apoptosis and senescence through activating the ROS-mediated PI3K/Akt pathway
Wenping Wang et al.
BIOSCIENCE REPORTS (2018)
Therapeutic Potential of Naringin for Intervertebral Disc Degeneration: Involvement of Autophagy Against Oxidative Stress-Induced Apoptosis in Nucleus Pulposus Cells
Zengjie Zhang et al.
AMERICAN JOURNAL OF CHINESE MEDICINE (2018)
Caffeine Protects Skin from Oxidative Stress-Induced Senescence through the Activation of Autophagy
Yi-Fang Li et al.
THERANOSTICS (2018)
Association between menopause and lumbar disc degeneration: an MRI study of 1,566 women and 1,382 men
Chao Lou et al.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY (2017)
Oxidative stress, protein damage and repair in bacteria
Benjamin Ezraty et al.
NATURE REVIEWS MICROBIOLOGY (2017)
Autophagy Is a Protective Response to the Oxidative Damage to Endplate Chondrocytes in Intervertebral Disc: Implications for the Treatment of Degenerative Lumbar Disc
Ke Chen et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)
ROS: Crucial Intermediators in the Pathogenesis of Intervertebral Disc Degeneration
Chencheng Feng et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)
Defects of the vertebral end plate: implications for disc degeneration depend on size
Uruj Zehra et al.
SPINE JOURNAL (2017)
Treatment of chronic low back pain - new approaches on the horizon
Nebojsa Nick Knezevic et al.
JOURNAL OF PAIN RESEARCH (2017)
Inflammatory biomarkers of low back pain and disc degeneration: a review
Aysha N. Khan et al.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2017)
Salubrinal Suppresses IL-17-Induced Upregulation of MMP-13 and Extracellular Matrix Degradation Through the NF-kB Pathway in Human Nucleus Pulposus Cells
Zhixiao Yao et al.
INFLAMMATION (2016)
Molecular mechanisms of cell death in intervertebral disc degeneration (Review)
Fan Zhang et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2016)
Aging and age related stresses: a senescence mechanism of intervertebral disc degeneration
F. Wang et al.
OSTEOARTHRITIS AND CARTILAGE (2016)
The Natural Polyphenol Epigallocatechin Gallate Protects Intervertebral Disc Cells from Oxidative Stress
Olga Krupkova et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases
Pierpaola Davalli et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB Perspective
Heidi Martini-Stoica et al.
TRENDS IN NEUROSCIENCES (2016)
Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo
Deheng Chen et al.
CELL DEATH & DISEASE (2016)
mTOR: a pharmacologic target for autophagy regulation
Young Chul Kim et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Inflammation in intervertebral disc degeneration and regeneration
Maria Molinos et al.
JOURNAL OF THE ROYAL SOCIETY INTERFACE (2015)
Oxidative Stress and Adipocyte Biology: Focus on the Role of AGEs
Florence Boyer et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2015)
Excessive reactive oxygen species are therapeutic targets for intervertebral disc degeneration
Satoshi Suzuki et al.
ARTHRITIS RESEARCH & THERAPY (2015)
Oxidative stress and autophagy: the clash between damage and metabolic needs
G. Filomeni et al.
CELL DEATH AND DIFFERENTIATION (2015)
DISC IN FLAMES: ROLES OF TNF-α AND IL-1β IN INTERVERTEBRAL DISC DEGENERATION
Z. I. Johnson et al.
EUROPEAN CELLS & MATERIALS (2015)
Oxidative stress participates in age-related changes in rat lumbar intervertebral discs
Gang Hou et al.
ARCHIVES OF GERONTOLOGY AND GERIATRICS (2014)
Differential expression of extracellular-signal-regulated kinase 5 (ERK5) in normal and degenerated human nucleus pulposus tissues and cells
Weiguo Liang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Detection and interpretation of 8-oxodG and 8-oxoGua in urine, plasma and cerebrospinal fluid
Henrik E. Poulsen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2014)
Glutathione protects human nucleus pulposus cells from cell apoptosis and inhibition of matrix synthesis
Dazhi Yang et al.
CONNECTIVE TISSUE RESEARCH (2014)
Accelerated premature stress-induced senescence of young annulus fibrosus cells of rats by high glucose-induced oxidative stress
Jong-Soo Park et al.
INTERNATIONAL ORTHOPAEDICS (2014)
The Role Of Extracellular Matrix Elasticity and Composition In Regulating the Nucleus Pulposus Cell Phenotype in the Intervertebral Disc: A Narrative Review
Priscilla Y. Hwang et al.
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME (2014)
PROTEIN CARBONYLATION AS A MAJOR HALLMARK OF OXIDATIVE DAMAGE: UPDATE OF ANALYTICAL STRATEGIES
Maria Fedorova et al.
MASS SPECTROMETRY REVIEWS (2014)
Autophagy-a key player in cellular and body metabolism
Kook Hwan Kim et al.
NATURE REVIEWS ENDOCRINOLOGY (2014)
Role of cytokines in intervertebral disc degeneration: pain and disc content
Makarand V. Risbud et al.
NATURE REVIEWS RHEUMATOLOGY (2014)
Increased Macroautophagy in the Pathological Process of Intervertebral Disc Degeneration in Rats
Wei Ye et al.
CONNECTIVE TISSUE RESEARCH (2013)
High glucose-induced oxidative stress promotes autophagy through mitochondrial damage in rat notochordal cells
Eun-Young Park et al.
INTERNATIONAL ORTHOPAEDICS (2013)
Apoptosis, senescence, and autophagy in rat nucleus pulposus cells: Implications for diabetic intervertebral disc degeneration
Libo Jiang et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2013)
Oxidative Stress and Nucleic Acid Oxidation in Patients with Chronic Kidney Disease
Chih-Chien Sung et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
Oxidative protein damage and the proteasome
S. Grimm et al.
AMINO ACIDS (2012)
Age-Related Oxidative Stress Compromises Endosomal Proteostasis
Elvira S. Cannizzo et al.
CELL REPORTS (2012)
Free Radical Lipid Peroxidation: Mechanisms and Analysis
Huiyong Yin et al.
CHEMICAL REVIEWS (2011)
Mitochondrial DNA damage is involved in apoptosis caused by pro-inflammatory cytokines in human OA chondrocytes
J. Kim et al.
OSTEOARTHRITIS AND CARTILAGE (2010)
Senescence mechanisms of nucleus pulposus chondrocytes in human intervertebral discs
Ki-Won Kim et al.
SPINE JOURNAL (2009)
Many roads lead to oncogene-induced senescence
S. Courtois-Cox et al.
ONCOGENE (2008)
Senescence in cells of the aging and degenerating intervertebral disc -: Immunolocalization of senescence-associated β-galactosidase in human and sand rat discs
Helen E. Gruber et al.
SPINE (2007)
Dynamic redox control of NF-κB through glutaredoxin-regulated S-glutathionylation of inhibitory κB kinase β
Niki L. Reynaert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Senescence in human intervertebral discs
S. Roberts et al.
EUROPEAN SPINE JOURNAL (2006)
Protein aggregation and neurodegenerative disease
CA Ross et al.
NATURE MEDICINE (2004)