Related references
Note: Only part of the references are listed.Canagliflozin primes antitumor immunity by triggering PD-L1 degradation in endocytic recycling
Ling Ding et al.
JOURNAL OF CLINICAL INVESTIGATION (2023)
Obesity alters pathology and treatment response in inflammatory disease
Sagar P. Bapat et al.
NATURE (2022)
The SGLT2 inhibitor canagliflozin in heart failure: the CHIEF-HF remote, patient-centered randomized trial
John A. Spertus et al.
NATURE MEDICINE (2022)
Mitochondrial aspartate regulates TNF biogenesis and autoimmune tissue inflammation
Bowen Wu et al.
NATURE IMMUNOLOGY (2021)
Type I interferons affect the metabolic fitness of CD8+ T cells from patients with systemic lupus erythematosus
Norzawani Buang et al.
NATURE COMMUNICATIONS (2021)
Efficacy and Safety of Metformin Use in Rheumatoid Arthritis: A Randomized Controlled Study
Mahmoud Gharib et al.
FRONTIERS IN PHARMACOLOGY (2021)
Metabolic preconditioning in CD4+T cells restores inducible immune tolerance in lupus-prone mice
Christopher S. Wilson et al.
JCI INSIGHT (2021)
Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity
Stefano Angiari et al.
CELL METABOLISM (2020)
Mitochondrial Oxidative Phosphorylation Regulates the Fate Decision between Pathogenic Th17 and Regulatory T Cells
Boyoung Shin et al.
CELL REPORTS (2020)
Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation
Julia M. Marchingo et al.
ELIFE (2020)
Adherence to metformin and the onset of rheumatoid arthritis: a population-based cohort study
M. E. Naffaa et al.
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2020)
T Cell Metabolism: A New Perspective on Th17/Treg Cell Imbalance in Systemic Lupus Erythematosus
Juan Shan et al.
FRONTIERS IN IMMUNOLOGY (2020)
Metformin as a Potential Agent in the Treatment of Multiple Sclerosis
Angela Dziedzic et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
T Cells in Autoimmunity-Associated Cardiovascular Diseases
Daniella Muallem Schwartz et al.
FRONTIERS IN IMMUNOLOGY (2020)
Human Plasma-like Medium Improves T Lymphocyte Activation
Michael A. Leney-Greene et al.
ISCIENCE (2020)
Effects of metformin on disease flares in patients with systemic lupus erythematosus: post hoc analyses from two randomised trials
Fangfang Sun et al.
LUPUS SCIENCE & MEDICINE (2020)
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy
V. Perkovic et al.
NEW ENGLAND JOURNAL OF MEDICINE (2019)
Akt and STAT5 mediate naive human CD4+T-cell early metabolic response to TCR stimulation
Nicholas Jones et al.
NATURE COMMUNICATIONS (2019)
Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells
Bjorn Neumann et al.
CELL STEM CELL (2019)
Metformin attenuates autoimmune disease of the neuromotor system in animal models of myasthenia gravis
Yingzhe Cui et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2019)
Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring
Valentina Pucino et al.
CELL METABOLISM (2019)
Canagliflozin mediated dual inhibition of mitochondrial glutamate dehydrogenase and complex I: an off-target adverse effect
Philipp F. Secker et al.
CELL DEATH & DISEASE (2018)
Metformin and Autoimmunity: A New Deal of an Old Drug
Francesco Ursini et al.
FRONTIERS IN IMMUNOLOGY (2018)
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
Marc O. Johnson et al.
CELL (2018)
Glutathione Primes T Cell Metabolism for Inflammation
Tak W. Mak et al.
IMMUNITY (2017)
Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements
Shona A. Mookerjee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Immunometabolism in early and late stages of rheumatoid arthritis
Cornelia M. Weyand et al.
NATURE REVIEWS RHEUMATOLOGY (2017)
Metabolic Adaptation of Human CD4+ and CD8+ T-cells to T-cell Receptor-Mediated Stimulation
Nicholas Jones et al.
FRONTIERS IN IMMUNOLOGY (2017)
Immunologic Effects of Metformin and Pioglitazone Treatment on Metabolic Syndrome and Multiple Sclerosis
Laura Negrotto et al.
JAMA NEUROLOGY (2016)
The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration
Linda A. Villani et al.
MOLECULAR METABOLISM (2016)
Normalization of CD4+ T cell metabolism reverses lupus
Yiming Yin et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Pharmacodynamics, Efficacy and Safety of Sodium-Glucose Co-Transporter Type 2 (SGLT2) Inhibitors for the Treatment of Type 2 Diabetes Mellitus
Andre J. Scheen
DRUGS (2015)
T-cell metabolism in autoimmune disease
Zhen Yang et al.
ARTHRITIS RESEARCH & THERAPY (2015)
Normalizing glycosphingolipids restores function in CD4+ T cells from lupus patients
Georgia McDonald et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Pro-inflammatory human Th17 cells selectively express P-glycoprotein and are refractory to glucocorticoids
Radha Ramesh et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
A Proteomic Ruler for Protein Copy Number and Concentration Estimation without Spike-in Standards
Jacek R. Wisniewski et al.
MOLECULAR & CELLULAR PROTEOMICS (2014)
Peroxisome proliferator-activated receptor-γ agonist pioglitazone suppresses experimental autoimmune uveitis
Yoko Okunuki et al.
EXPERIMENTAL EYE RESEARCH (2013)
Nonclinical Toxicology Assessments Support the Chronic Safety of Dapagliflozin, a First-in-Class Sodium-Glucose Cotransporter 2 Inhibitor
Mark Tirmenstein et al.
INTERNATIONAL JOURNAL OF TOXICOLOGY (2013)
Pharmacokinetics and Pharmacodynamics of Canagliflozin, a Sodium Glucose Co-Transporter 2 Inhibitor, in Subjects With Type 2 Diabetes Mellitus
Damayanthi Devineni et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2013)
Rapid effector function of memory CD8+ T cells requires an immediate-early glycolytic switch
Patrick M. Gubser et al.
NATURE IMMUNOLOGY (2013)
The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
Ruoning Wang et al.
IMMUNITY (2011)
Metformin Attenuated the Autoimmune Disease of the Central Nervous System in Animal Models of Multiple Sclerosis
Narender Nath et al.
JOURNAL OF IMMUNOLOGY (2009)
MAPK, Phosphatidylinositol 3-Kinase, and Mammalian Target of Rapamycin Pathways Converge at the Level of Ribosomal Protein S6 Phosphorylation to Control Metabolic Signaling in CD8 T Cells
Robert J. Salmond et al.
JOURNAL OF IMMUNOLOGY (2009)
The Immunological Genome Project: networks of gene expression in immune cells
Tracy S. P. Heng et al.
NATURE IMMUNOLOGY (2008)
The role of the T cell in autoimmune inflammation
A Skapenko et al.
ARTHRITIS RESEARCH & THERAPY (2005)