Versatile use of bat ACE2 for cellular entry by MERS-CoV-like viruses

Cellular entry receptors for bat MERS-CoV-like viruses NeoCoV and PDF-2180 were unknown, leaving their zoonotic potential ambiguous. A recent study by Xiong et al. published in Nature identified bat ACE2 as the cellular entry receptor for both viruses, highlighting the ability of coronaviruses to utilize a range of entry receptors.

Automated summary

A recent study published in Nature identified bat ACE2 as the cellular entry receptor for NeoCoV and PDF-2180, revealing the ability of coronaviruses to utilize multiple entry receptors.