4.7 Article

Antimicrobial peptide moricin induces ROS mediated caspase-dependent apoptosis in human triple-negative breast cancer via suppression of notch pathway

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Novel Perspective for Treatment of Mycoplasma Infections: A Promising Future

Mansoor Khaledi et al.

Summary: Mycoplasma is a bacterium without a cell wall, making it naturally resistant to antibiotics. Some species are pathogenic to humans, and antibiotic-resistant strains are increasing worldwide.

INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS (2022)

Article Chemistry, Physical

Rationally designed short cationic a-helical peptides with selective anticancer activity

Roja Hadianamrei et al.

Summary: The study introduced a new library of short cationic amphiphilic α-helical anticancer peptides with selective cytotoxicity against colorectal and cervical cancer, and investigated their anticancer mechanisms through a series of experiments.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2022)

Article Genetics & Heredity

Anticancer Peptide Prediction via Multi-Kernel CNN and Attention Model

Xiujin Wu et al.

Summary: This study presents a tool for identifying anticancer peptides based on a multi-kernel CNN and attention model, which outperforms other models and provides new research ideas for anticancer peptide prediction.

FRONTIERS IN GENETICS (2022)

Review Pharmacology & Pharmacy

Development of Anticancer Peptides Using Artificial Intelligence and Combinational Therapy for Cancer Therapeutics

Ji Su Hwang et al.

Summary: Cancer is a disease characterized by abnormal cell growth, genome alterations, and invasion/spread to other parts of the body. Anticancer peptides (ACPs) have advantages such as high specificity, low toxicity, and low immunogenicity, and the application of artificial intelligence can save time and reduce costs in their development. Combination therapy of classical approaches and ACPs might be an impactful method to improve cancer treatment efficiency.

PHARMACEUTICS (2022)

Article Microbiology

Endofungal Rhizobium species enhance arsenic tolerance in colonized host plant under arsenic stress

Imran Ahmad et al.

Summary: The endofungal Rhizobium species Si001 plays a beneficial role in promoting plant growth and tolerance against As stress, reducing As accumulation and improving pigment content and photosynthesis in crop produce.

ARCHIVES OF MICROBIOLOGY (2022)

Article Oncology

Current and future burden of breast cancer: Global statistics for 2020 and 2040

Melina Arnold et al.

Summary: Breast cancer is the most commonly diagnosed cancer worldwide, with over 2.3 million new cases and 685,000 deaths in 2020. There is significant geographic variation in incidence rates, with lower rates in some Asian and African countries and higher rates in countries like Australia, New Zealand, Northern America, and parts of Europe. Mortality rates show less variation, but transitioning countries still bear a disproportionate burden of breast cancer deaths. By 2040, the burden of breast cancer is predicted to increase further due to population growth and ageing. Global efforts are needed to address this growing burden, especially in transitioning countries where incidence rates are rising rapidly and mortality rates remain high.

BREAST (2022)

Article Integrative & Complementary Medicine

Economic evaluation of a national vitamin D supplementation program among Iranian adolescents for the prevention of adulthood type 2 diabetes mellitus

Narges Zandieh et al.

Summary: This study evaluates the cost-effectiveness of vitamin D supplementation in preventing type 2 diabetes among Iranian adolescents, and finds that it is a cost-effective strategy to reduce the risk of diabetes in adulthood.

BMC COMPLEMENTARY MEDICINE AND THERAPIES (2022)

Letter Biochemistry & Molecular Biology

Mutations of MSH5 in nonobstructive azoospermia (NOA) and rescued via in vivo gene editing

Min Chen et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2022)

Article Oncology

Birinapant Enhances Gemcitabine's Antitumor Efficacy in Triple-Negative Breast Cancer by Inducing Intrinsic Pathway-Dependent Apoptosis

Xuemei Xie et al.

Summary: The study demonstrates the therapeutic potential of birinapant to enhance the antitumor efficacy of gemcitabine in TNBC by targeting the IAP family of proteins, showing a strong synergistic effect between the two drugs.

MOLECULAR CANCER THERAPEUTICS (2021)

Article Multidisciplinary Sciences

Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study

Hana Storkanova et al.

Summary: According to the study, plasma levels of Hsp90 are increased in patients with systemic sclerosis compared to healthy controls, and are associated with increased inflammatory activity, worsened lung function, and extent of skin involvement in patients with diffuse cutaneous systemic sclerosis. In patients with systemic sclerosis-associated interstitial lung disease treated with cyclophosphamide, baseline Hsp90 levels can predict changes in DLCO over 12 months of therapy.

SCIENTIFIC REPORTS (2021)

Article Microbiology

Dual Antimicrobial and Antiproliferative Activity of TcPaSK Peptide Derived from a Tribolium castaneum Insect Defensin

Aida Robles-Fort et al.

Summary: Antimicrobial peptides (AMPs) are important in the innate immune system, offering potential for fighting infections with slower development of resistance. The TcPaSK peptide, derived from Tribolium castaneum insect defensin 3, shows promise as a dual agent against both infections and proliferation, making it a versatile molecule for novel therapeutic developments.

MICROORGANISMS (2021)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Biochemistry & Molecular Biology

Cytotoxicity of Moringa oleifera fruits on human liver cancer and molecular docking analysis of bioactive constituents against caspase-3 enzyme

Sahabjada Siddiqui et al.

Summary: The study demonstrated the potential anticancer activity of Moringa oleifera fruit extract against human liver cancer cells by inducing apoptosis and activating caspase-3 enzyme. In silico analysis confirmed the good binding interaction between bioactive components of Moringa oleifera fruits and caspase-3 enzyme, showing drug-like candidates with no predicted toxicity. This suggests that Moringa oleifera fruit could serve as a valuable source for developing anticancer drugs against liver cancer.

JOURNAL OF FOOD BIOCHEMISTRY (2021)

Review Biochemistry & Molecular Biology

Programmed cell death, redox imbalance, and cancer therapeutics

Xiaofeng Dai et al.

Summary: Cancer cells have higher internal redox levels compared to healthy cells, which can lead to programmed cell death if there is redox imbalance. Understanding the differences and similarities among programmed cell death events in relation to redox imbalance is crucial for improved control over malignant cells and therapeutic approach design. Cold atmospheric plasma is identified as a potential redox controller with translational benefits in clinics.

APOPTOSIS (2021)

Review Oncology

Recent advances in radiotherapy of breast cancer

Jan Haussmann et al.

RADIATION ONCOLOGY (2020)

Review Oncology

Anticancer peptide: Physicochemical property, functional aspect and trend in clinical application (Review)

Wararat Chiangjong et al.

INTERNATIONAL JOURNAL OF ONCOLOGY (2020)

Review Biochemistry & Molecular Biology

Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects

Hongyi Li et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)

Article Oncology

Methylation-Based Biological Age and Breast Cancer Risk

Jacob K. Kresovich et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2019)

Article Cell Biology

Buforin IIb induced cell cycle arrest in liver cancer

Dan Li et al.

ANIMAL CELLS AND SYSTEMS (2019)

Article Integrative & Complementary Medicine

Investigation of anti-cancer and migrastatic properties of novel curcumin derivatives on breast and ovarian cancer cell lines

Jinsha Koroth et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2019)

Article Public, Environmental & Occupational Health

Adherence to lifestyle-related cancer prevention guidelines and breast cancer incidence and mortality

Gabriella Cifu et al.

ANNALS OF EPIDEMIOLOGY (2018)

Article Multidisciplinary Sciences

Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness

Michiru Nishita et al.

SCIENTIFIC REPORTS (2017)

Article Multidisciplinary Sciences

Anticancer properties of a defensin like class IId bacteriocin Laterosporulin10

Piyush Baindara et al.

SCIENTIFIC REPORTS (2017)

Review Biology

Diversity, evolution and medical applications of insect antimicrobial peptides

Eleftherios Mylonakis et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2016)

Article Biochemistry & Molecular Biology

Prediction of anticancer peptides against MCF-7 breast cancer cells from the peptidomes of Achatina fulica mucus fractions

Teerasak E-kobon et al.

COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2016)

Article Chemistry, Multidisciplinary

Enhancement of cytotoxicity of antimicrobial peptide magainin II in tumor cells by bombesin-targeted delivery

Shan Liu et al.

ACTA PHARMACOLOGICA SINICA (2011)

Article Biochemistry & Molecular Biology

Solution structure, antibacterial activity, and expression profile of Manduco sexto moricin

Huaien Dai et al.

JOURNAL OF PEPTIDE SCIENCE (2008)

Article Biochemical Research Methods

Solid-phase peptide synthesis: from standard procedures to the synthesis of difficult sequences

Irene Coin et al.

NATURE PROTOCOLS (2007)

Article Medical Laboratory Technology

Arterial and venous smooth-muscle cells differ in their responses to antiproliferative drugs

SJ Kim et al.

JOURNAL OF LABORATORY AND CLINICAL MEDICINE (2004)

Article Biochemistry & Molecular Biology

Solution structure of moricin, an antibacterial peptide, isolated from the silkworm Bombyx mori

H Hemmi et al.

FEBS LETTERS (2002)

Review Multidisciplinary Sciences

The biochemistry of apoptosis

MO Hengartner

NATURE (2000)